Searching for up to 100 curated homologs for Ga0059261_3653 FitnessBrowser__Korea:Ga0059261_3653 (276 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pstB / OMNI|NTL02SP1895 phosphate ABC transporter, ATP-binding protein; EC 3.6.3.27 from Streptococcus pneumoniae R6 (see 2 papers)
59% identity, 90% coverage of query (329 bits)
PstB / b3725 phosphate ABC transporter ATP binding subunit (EC 7.3.2.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
PstB / P0AAH0 phosphate ABC transporter ATP binding subunit (EC 7.3.2.1) from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.7.1 / P0AAH0 Phosphate import ATP-binding protein PstB aka PhoT aka B3725, component of Phosphate porter, PhoSPstABC. Serves as both a transporter and a sensor for transcriptional activation of the pho regulon in the presence of low external phosphate. The unphosphorylated EIIANtr protein of the PTS (TC# 4.A) activates PhoR, the senor kinase that phosphorylates the response regulator, PhoB, that activates the pho regulon from Escherichia coli (see 6 papers)
pstB phosphate import ATP-binding protein pstB; EC 3.6.3.27 from Escherichia coli K12 (see 6 papers)
59% identity, 91% coverage of query (322 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
59% identity, 91% coverage of query (322 bits)
TC 3.A.1.7.5 / O51236 Phosphate import ATP-binding protein PstB, component of The phosphate transporter, PstABCS from Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
54% identity, 92% coverage of query (314 bits)
TC 3.A.1.7.3 / C3KCB5 Putative ABC transporter ATP-binding protein, component of High-affinity phosphate-specific permease, PstAB/PhoS. The 3-d structure of PhoS = (PBP) = PfluDING) has been solved at high resolution by x-ray crystallography (Ahn et al. 2007) with phosphate bound (4F1U and 4F1V; 0.95Å resolution) and with arsenate bound (4F18 and 4F19; 0.88Å resolution) (Elias et al. 2012). Phosphate binds with 500-fold higher affinity than arsenate due to a dense and rigid network of ion-dipole interactions (Elias et al. 2012). The PBP from Halomonas sp from Pseudomonas fluorescens (strain SBW25)
53% identity, 93% coverage of query (288 bits)
TC 3.A.1.7.2 / P0C560 PstB, component of Phosphate transporter, PstSCAB from Mycobacterium smegmatis (see paper)
59% identity, 90% coverage of query (288 bits)
PSTB1_MYCTU / P9WQL1 Phosphate import ATP-binding protein PstB 1; ABC phosphate transporter 1; Phosphate-transporting ATPase 1; EC 7.3.2.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
58% identity, 88% coverage of query (275 bits)
PSTB2_MYCTU / P9WQK9 Phosphate import ATP-binding protein PstB 2; ABC phosphate transporter 2; Phosphate-transporting ATPase 2; EC 7.3.2.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
50% identity, 87% coverage of query (244 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
37% identity, 87% coverage of query (153 bits)
ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168) (see paper)
36% identity, 85% coverage of query (152 bits)
TC 3.A.1.3.14 / P39456 TcyC (YckI), component of Uptake system for L-cystine from Bacillus subtilis (see 7 papers)
36% identity, 88% coverage of query (152 bits)
TC 3.A.1.3.25 / Q9CES4 Glutamine ABC transporter ATP-binding protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
36% identity, 85% coverage of query (151 bits)
ANTRA_HALVD / D4GSY7 Probable anion import ATP-binding protein HVO_1886; EC 7.3.2.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
35% identity, 96% coverage of query (149 bits)
GLUA_CORGL / P48243 Glutamate transport ATP-binding protein GluA; Glutamate uptake system protein GluA; EC 7.4.2.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48243 GluA aka CGL1950, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
37% identity, 87% coverage of query (149 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
35% identity, 86% coverage of query (147 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
35% identity, 86% coverage of query (147 bits)
2olkA Abc protein artp in complex with adp-beta-s
35% identity, 86% coverage of query (147 bits)
2oljA Abc protein artp in complex with adp/mg2+
35% identity, 86% coverage of query (147 bits)
GltL / b0652 glutamate/aspartate ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see paper)
GltL / P0AAG3 glutamate/aspartate ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.4 / P0AAG3 Glutamate/aspartate transport ATP-binding protein GltL aka B0652, component of Glutamate/aspartate porter from Escherichia coli (see 3 papers)
38% identity, 87% coverage of query (145 bits)
TC 3.A.1.3.12 / P73721 BgtA aka SLR1735, component of Arginine/lysine/histidine/glutamine porter (see paper)
37% identity, 85% coverage of query (144 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
35% identity, 85% coverage of query (144 bits)
7ahhC Opua inhibited inward-facing, sbd docked
32% identity, 84% coverage of query (122 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
32% identity, 84% coverage of query (122 bits)
7ahdC Opua (e190q) occluded
32% identity, 83% coverage of query (118 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
35% identity, 86% coverage of query (117 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
35% identity, 86% coverage of query (117 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
32% identity, 83% coverage of query (112 bits)
4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
32% identity, 88% coverage of query (112 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
31% identity, 83% coverage of query (110 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
31% identity, 83% coverage of query (110 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
31% identity, 83% coverage of query (110 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
31% identity, 89% coverage of query (110 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
31% identity, 81% coverage of query (109 bits)
7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
31% identity, 89% coverage of query (108 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
32% identity, 80% coverage of query (108 bits)
6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
32% identity, 78% coverage of query (108 bits)
7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
32% identity, 78% coverage of query (108 bits)
7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
32% identity, 78% coverage of query (108 bits)
7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
32% identity, 78% coverage of query (108 bits)
7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
32% identity, 78% coverage of query (108 bits)
7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
32% identity, 78% coverage of query (108 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
31% identity, 79% coverage of query (107 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
31% identity, 79% coverage of query (107 bits)
4xwkA P-glycoprotein co-crystallized with bde-100
31% identity, 79% coverage of query (107 bits)
6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
31% identity, 79% coverage of query (107 bits)
3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
31% identity, 79% coverage of query (107 bits)
3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
31% identity, 79% coverage of query (107 bits)
7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
31% identity, 79% coverage of query (107 bits)
5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
33% identity, 81% coverage of query (107 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
31% identity, 81% coverage of query (107 bits)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
36% identity, 78% coverage of query (107 bits)
6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
32% identity, 78% coverage of query (107 bits)
6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
36% identity, 76% coverage of query (106 bits)
5koyA Mouse pgp 34 linker deleted bound with atp
30% identity, 79% coverage of query (105 bits)
6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
30% identity, 79% coverage of query (105 bits)
8ipsA / P23886 Cryo-em structure of heme transporter cyddc from escherichia coli in the inward facing heme loading state (see paper)
30% identity, 96% coverage of query (105 bits)
MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
31% identity, 78% coverage of query (105 bits)
7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
30% identity, 78% coverage of query (103 bits)
6s7pA Nucleotide bound abcb4
30% identity, 78% coverage of query (103 bits)
Build an alignment for Ga0059261_3653 and 59 homologs with ≥ 30% identity
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7zdaC If(apo/asym) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
29% identity, 96% coverage of query (103 bits)
7zdkC If(apo/asym) conformation of cyddc in amp-pnp(cydc)/amp-pnp(cydd) bound state (dataset-8)
29% identity, 96% coverage of query (103 bits)
7zdfC If(heme/confined) conformation of cyddc in amp-pnp(cydd) bound state (dataset-4)
29% identity, 96% coverage of query (103 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
32% identity, 85% coverage of query (103 bits)
7zdbC If(heme/bound) conformation of cyddc in adp+pi(cydc)/atp(cydd) bound state (dataset-2)
31% identity, 84% coverage of query (103 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
32% identity, 85% coverage of query (103 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
32% identity, 85% coverage of query (103 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
30% identity, 79% coverage of query (102 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
30% identity, 79% coverage of query (102 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
30% identity, 79% coverage of query (102 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
30% identity, 79% coverage of query (102 bits)
7zdtC Occ(apo/return) conformation of cyddc mutant (e500q.C) in atp(cydc) bound state (dataset-18)
29% identity, 96% coverage of query (102 bits)
1mv5B Crystal structure of lmra atp-binding domain
33% identity, 72% coverage of query (102 bits)
1mv5A / Q9CHL8 Crystal structure of lmra atp-binding domain
33% identity, 72% coverage of query (102 bits)
1g291 / Q9YGA6 Malk (see paper)
30% identity, 84% coverage of query (102 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
28% identity, 83% coverage of query (102 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
30% identity, 83% coverage of query (102 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
30% identity, 79% coverage of query (101 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
28% identity, 88% coverage of query (99.4 bits)
Q00748 Multidrug resistance protein homolog 65; P-glycoprotein 65; EC 7.6.2.2 from Drosophila melanogaster (Fruit fly)
31% identity, 78% coverage of query (99.0 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
31% identity, 84% coverage of query (98.6 bits)
4aywA Structure of the human mitochondrial abc transporter, abcb10 (plate form)
30% identity, 87% coverage of query (98.6 bits)
8jwfA / Q7K6A5 Cryo-em structure of plasmodium falciparum multidrug resistance protein 1 with h1 helix in complex with mfq (see paper)
30% identity, 85% coverage of query (98.6 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
31% identity, 83% coverage of query (97.4 bits)
8jwiA Cryo-em structure of the outward-facing plasmodium falciparum multidrug resistance protein 1
30% identity, 85% coverage of query (97.4 bits)
IRTA_MYCT3 / G7CBF5 Mycobactin import ATP-binding/permease protein IrtA; EC 7.2.2.- from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
31% identity, 84% coverage of query (97.1 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
26% identity, 89% coverage of query (97.1 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
29% identity, 82% coverage of query (96.7 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
25% identity, 89% coverage of query (96.7 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
25% identity, 89% coverage of query (96.7 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
25% identity, 89% coverage of query (96.7 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
25% identity, 89% coverage of query (96.7 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
25% identity, 89% coverage of query (96.7 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
25% identity, 89% coverage of query (96.7 bits)
7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
29% identity, 88% coverage of query (96.7 bits)
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
29% identity, 88% coverage of query (96.7 bits)
8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
31% identity, 83% coverage of query (96.3 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
26% identity, 85% coverage of query (95.9 bits)
ABCBB_RAT / O70127 Bile salt export pump; ATP-binding cassette sub-family B member 11; Sister of P-glycoprotein; EC 7.6.2.- from Rattus norvegicus (Rat) (see 12 papers)
31% identity, 84% coverage of query (95.9 bits)
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
29% identity, 88% coverage of query (95.1 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
29% identity, 82% coverage of query (94.7 bits)
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Lawrence Berkeley National Laboratory