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Searching for up to 100 curated homologs for H281DRAFT_00358 FitnessBrowser__Burk376:H281DRAFT_00358 (312 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

larA / A2QBD7 L-arabinose reductase LarA (EC 1.1.1.431; EC 1.1.1.21) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 5 papers)
    44% identity, 90% coverage of query (238 bits)

Q2TJA5 prostaglandin-F synthase (EC 1.1.1.188) from Sus scrofa (see paper)
    40% identity, 97% coverage of query (227 bits)

AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
    40% identity, 95% coverage of query (226 bits)

AK1A1_RAT / P51635 Aldo-keto reductase family 1 member A1; 3-DG-reducing enzyme; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Rattus norvegicus (Rat) (see 4 papers)
P51635 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Rattus norvegicus (see 2 papers)
    40% identity, 95% coverage of query (226 bits)

3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
    41% identity, 91% coverage of query (226 bits)

3cv7A Crystal structure of porcine aldehyde reductase ternary complex
    41% identity, 91% coverage of query (226 bits)

AK1A1_HUMAN / P14550 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Homo sapiens (Human) (see 4 papers)
    39% identity, 95% coverage of query (225 bits)

Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
    41% identity, 88% coverage of query (224 bits)

1xf0A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (akr1c3) complexed with delta4-androstene-3,17-dione and NADP
    40% identity, 93% coverage of query (223 bits)

D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
    40% identity, 91% coverage of query (220 bits)

Q95JH5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see paper)
    40% identity, 91% coverage of query (219 bits)

AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
    42% identity, 91% coverage of query (219 bits)

AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
    42% identity, 91% coverage of query (219 bits)

AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
    40% identity, 91% coverage of query (218 bits)

AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
    40% identity, 91% coverage of query (218 bits)

AK1C4_MACFU / Q95JH4 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase homolog; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Macaca fuscata fuscata (Japanese macaque) (see paper)
    40% identity, 91% coverage of query (218 bits)

4zfcB / P42330 Crystal structure of akr1c3 complexed with glicazide (see paper)
    39% identity, 97% coverage of query (218 bits)

Q7S3U4 carbonyl reductase (NADPH) (EC 1.1.1.184) from Neurospora crassa (see paper)
    44% identity, 88% coverage of query (218 bits)

AKR1C3 / P42330 aldo-keto reductase family 1 member C3 (EC 1.1.1.64; EC 1.1.1.213; EC 1.1.1.112; EC 1.1.1.357; EC 1.1.1.188) from Homo sapiens (see 15 papers)
AK1C3_HUMAN / P42330 Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; EC 1.1.1.-; EC 1.1.1.210; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.188; EC 1.1.1.239; EC 1.1.1.64 from Homo sapiens (Human) (see 14 papers)
P42330 prostaglandin-F synthase (EC 1.1.1.188); aldose reductase (EC 1.1.1.21); 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51); 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62); testosterone 17beta-dehydrogenase (NADP+) (EC 1.1.1.64); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 38 papers)
    39% identity, 97% coverage of query (218 bits)

4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
    40% identity, 91% coverage of query (218 bits)

AK1CA_RAT / D3ZF77 Aldo-keto reductase family 1 member C15; RAKc; EC 1.1.1.-; EC 1.1.1.216 from Rattus norvegicus (Rat) (see 4 papers)
    41% identity, 91% coverage of query (218 bits)

4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    40% identity, 91% coverage of query (218 bits)

2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
    40% identity, 91% coverage of query (218 bits)

7x3lA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07044
    39% identity, 97% coverage of query (218 bits)

1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
    40% identity, 91% coverage of query (218 bits)

4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    40% identity, 91% coverage of query (218 bits)

4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
    40% identity, 91% coverage of query (218 bits)

1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
    40% identity, 91% coverage of query (218 bits)

2f38A Crystal structure of prostaglandin f synathase containing bimatoprost
    39% identity, 93% coverage of query (218 bits)

1ry8A Prostaglandin f synthase complexed with NADPH and rutin
    39% identity, 93% coverage of query (218 bits)

1ry0A Structure of prostaglandin f synthase with prostaglandin d2
    39% identity, 93% coverage of query (218 bits)

8i0cA Crystal structure of aldo-keto reductase 1c3 complexed with compound s0703
    39% identity, 93% coverage of query (217 bits)

7c7hA Crystal structures of akr1c3 ternary complex with NADP+ and the chromene derivative 2l
    39% identity, 93% coverage of query (217 bits)

7c7gA Crystal structures of akr1c3 ternary complex with NADP+ and the chromene derivative 2j
    39% identity, 93% coverage of query (217 bits)

8bbsA Structure of akr1c3 in complex with a bile acid fused tetrazole inhibitor
    39% identity, 93% coverage of query (217 bits)

6gxkA Crystal structure of aldo-keto reductase 1c3 (akr1c3) complexed with inhibitor.
    39% identity, 93% coverage of query (217 bits)

6f78A Potent and selective aldo-keto reductase 1c3 (akr1c3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid
    39% identity, 93% coverage of query (217 bits)

6a7bA Akr1c3 complexed with new inhibitor with novel scaffold
    39% identity, 93% coverage of query (217 bits)

7wqsA Crystal structure of aldo-keto reductase 1c3 complexed with compound 25
    39% identity, 93% coverage of query (217 bits)

7wqrA Crystal structure of aldo-keto reductase 1c3 complexed with compound 28
    39% identity, 93% coverage of query (217 bits)

7wqmA Crystal structure of aldo-keto reductase 1c3 complexed with compound 24
    39% identity, 93% coverage of query (217 bits)

6f2uA Potent and selective aldo-keto reductase 1c3 (akr1c3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid
    39% identity, 93% coverage of query (217 bits)

3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
    41% identity, 87% coverage of query (217 bits)

7x3mA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07045
    39% identity, 93% coverage of query (217 bits)

5hnuC Crystal structure of akr1c3 complexed with octyl gallate
    39% identity, 93% coverage of query (217 bits)

5hntA Crystal structure of akr1c3 complexed with cape
    39% identity, 93% coverage of query (217 bits)

4yvxA Crystal structure of akr1c3 complexed with glimepiride
    39% identity, 93% coverage of query (217 bits)

4yvvA Crystal structure of akr1c3 complexed with glibenclamide
    39% identity, 93% coverage of query (217 bits)

4xveA 17beta-hsd5 in complex with 3-pentyl-2-[(pyridin-2-ylmethyl)sulfanyl]- 7-(pyrrolidin-1-ylcarbonyl)quinazolin-4(3h)-one
    39% identity, 93% coverage of query (217 bits)

4wduA 17beta-hsd5 in complex with 4-chloro-n-(4-chlorobenzyl)-5-nitro-1h- pyrazole-3-carboxamide
    39% identity, 93% coverage of query (217 bits)

4wdtA 17beta-hsd5 in complex with 2-nitro-5-(phenylsulfonyl)phenol
    39% identity, 93% coverage of query (217 bits)

4famA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)benzoic acid (17)
    39% identity, 93% coverage of query (217 bits)

4dbwA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (akr1c3) in complex with NADP+ and 2'-desmethyl-indomethacin
    39% identity, 93% coverage of query (217 bits)

4dbuA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (akr1c3) in complex with NADP+ and 3-((4 -(trifluoromethyl)phenyl) amino)benzoic acid
    39% identity, 93% coverage of query (217 bits)

4dbsA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (akr1c3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl) amino]benzoic acid
    39% identity, 93% coverage of query (217 bits)

1s2cA Crystal structures of prostaglandin d2 11-ketoreductase in complex with the non-steroidal anti-inflammatory drugs flufenamic acid and indomethacin
    39% identity, 93% coverage of query (217 bits)

1s2aA Crystal structures of prostaglandin d2 11-ketoreductase in complex with the non-steroidal anti-inflammatory drugs flufenamic acid and indomethacin
    39% identity, 93% coverage of query (217 bits)

1s1pA Crystal structures of prostaglandin d2 11-ketoreductase (akr1c3) in complex with the non-steroidal anti- inflammatory drugs flufenamic acid and indomethacin
    39% identity, 93% coverage of query (217 bits)

4jtrB Akr1c2 complex with ibuprofen
    41% identity, 87% coverage of query (217 bits)

4jtrA Akr1c2 complex with ibuprofen
    41% identity, 87% coverage of query (217 bits)

4jtqA Akr1c2 complex with flurbiprofen
    41% identity, 87% coverage of query (217 bits)

4jqaA Akr1c2 complex with mefenamic acid
    41% identity, 87% coverage of query (217 bits)

4jq4A Akr1c2 complex with indomethacin
    41% identity, 87% coverage of query (217 bits)

4jq3A Akr1c2 complex with zomepirac
    41% identity, 87% coverage of query (217 bits)

4jq2A Akr1c2 complex with sulindac
    41% identity, 87% coverage of query (217 bits)

4jq1A Akr1c2 complex with naproxen
    41% identity, 87% coverage of query (217 bits)

4wrhA Akr1c3 complexed with breakdown product of n-(tert-butyl)-2-(2-chloro- 4-(((3-mercapto-5-methyl-4h-1,2,4-triazol-4-yl)amino)methyl)-6- methoxyphenoxy)acetamide
    39% identity, 93% coverage of query (217 bits)

1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
    41% identity, 87% coverage of query (217 bits)

6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
    41% identity, 87% coverage of query (217 bits)

6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
    41% identity, 87% coverage of query (217 bits)

4yvpA Crystal structure of akr1c1 complexed with glibenclamide
    41% identity, 87% coverage of query (217 bits)

3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
    41% identity, 87% coverage of query (217 bits)

3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
    41% identity, 87% coverage of query (217 bits)

S4WCW2 D-xylose reductase (EC 1.1.1.307) from Spathaspora passalidarum (see paper)
    39% identity, 90% coverage of query (216 bits)

2ipjA Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant y24a in complex with NADP+ and epi-testosterone
    41% identity, 87% coverage of query (216 bits)

Q5DD64 aldose reductase (EC 1.1.1.21) from Schistosoma japonicum (see paper)
    42% identity, 90% coverage of query (215 bits)

T2HVB4 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Oryctolagus cuniculus (see paper)
    39% identity, 91% coverage of query (215 bits)

2fvlA / P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (akr1c4) complexed with NADP+
    40% identity, 91% coverage of query (214 bits)

AK1CN_HORSE / Q1XAA8 Aldo-keto reductase family 1 member C23; EC 1.1.1.- from Equus caballus (Horse) (see paper)
Q1XAA8 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Equus caballus (see paper)
    40% identity, 89% coverage of query (214 bits)

AKR1C4 / P17516 aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.357) from Homo sapiens (see 9 papers)
AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human) (see 11 papers)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens (see 4 papers)
    40% identity, 91% coverage of query (214 bits)

DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
    38% identity, 87% coverage of query (213 bits)

ALRA_DICDI / Q6IMN8 Aldose reductase A; ARA; Aldehyde reductase A; AlrA; EC 1.1.1.21 from Dictyostelium discoideum (Social amoeba) (see paper)
Q6IMN8 methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Dictyostelium discoideum (see paper)
    42% identity, 83% coverage of query (213 bits)

ALDX_SPOSA / P27800 Aldehyde reductase 1; ALR 1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase I; EC 1.1.1.2 from Sporidiobolus salmonicolor (Yeast-like fungus) (Sporobolomyces salmonicolor) (see 2 papers)
AAB17362.1 NADPH-dependent aldehyde reductase from Sporidiobolus salmonicolor (see paper)
    40% identity, 90% coverage of query (212 bits)

1q13A / P80508 Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone (see paper)
    39% identity, 93% coverage of query (212 bits)

P80508 Prostaglandin-E(2) 9-reductase; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; EC 1.1.1.189; EC 1.1.1.149 from Oryctolagus cuniculus (Rabbit)
    39% identity, 93% coverage of query (212 bits)

1q5mA Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH
    39% identity, 93% coverage of query (212 bits)

1zq5A Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor em1404
    39% identity, 93% coverage of query (210 bits)

4wdwA 17beta-hsd5 in complex with 3,6-dihydropyridin-1(2h)-yl(5-methyl-1h- indol-2-yl)methanone
    40% identity, 87% coverage of query (210 bits)

Q5FYA7 prostaglandin-F synthase (EC 1.1.1.188) from Canis lupus familiaris (see 2 papers)
    41% identity, 86% coverage of query (209 bits)

AK1CO_HORSE / Q6W8P9 Aldo-keto reductase family 1 member C23-like protein; Putative prostaglandin F synthase; EC 1.1.1.- from Equus caballus (Horse) (see paper)
    39% identity, 89% coverage of query (209 bits)

4xvdA 17beta-hsd5 in complex with 4-nitro-2-({4-[3-(trifluoromethyl) phenyl]piperazin-1-yl}methyl)phenol
    39% identity, 93% coverage of query (209 bits)

Q91WT7 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Mus musculus (see paper)
    40% identity, 84% coverage of query (208 bits)

Q7Z8L1 glycerol dehydrogenase (NADP+) (EC 1.1.1.72) from Aspergillus nidulans (see paper)
gldB NADP(+)-dependent glycerol dehydrogenase; EC 1.1.1.72 from Emericella nidulans (see paper)
    39% identity, 90% coverage of query (208 bits)

1afsA / P23457 Recombinant rat liver 3-alpha-hydroxysteroid dehydrogenase (3-alpha- hsd) complexed with NADP and testosterone (see paper)
    39% identity, 89% coverage of query (208 bits)

Akr1c9 / P23457 3α-hydroxysteroid dehydrogenase (A-specific) (EC 1.1.1.213) from Rattus norvegicus (see 9 papers)
DIDH_RAT / P23457 3-alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD; Hydroxyprostaglandin dehydrogenase; EC 1.1.1.50 from Rattus norvegicus (Rat) (see 2 papers)
P23457 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); NADPH dehydrogenase (quinone) (EC 1.6.5.10) from Rattus norvegicus (see 8 papers)
    39% identity, 89% coverage of query (208 bits)

AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
    42% identity, 82% coverage of query (207 bits)

3uweA Akr1c3 complexed with 3-phenoxybenzoic acid
    39% identity, 93% coverage of query (207 bits)

A0A0S2PJI4 D-xylose reductase (EC 1.1.1.307) from Spathaspora passalidarum (see paper)
    40% identity, 90% coverage of query (206 bits)

AKR4C8 / O80944 aldo-keto reductase family 4 member C8 (EC 1.1.1.21; EC 1.1.1.210) from Arabidopsis thaliana (see paper)
AKRC8_ARATH / O80944 Aldo-keto reductase family 4 member C8; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    37% identity, 95% coverage of query (206 bits)

3h7rA / O80944 Crystal structure of the plant stress-response enzyme akr4c8 (see paper)
    37% identity, 95% coverage of query (206 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory