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Searching for up to 100 curated homologs for H281DRAFT_00501 FitnessBrowser__Burk376:H281DRAFT_00501 (174 a.a.)

Found high-coverage hits (≥70%) to 50 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7zw9A / Q63SQ4 Crystal structure of a gamma-carbonic anhydrase from the pathogenic bacterium burkholderia pseudomallei (see paper)
    80% identity, 99% coverage of query (289 bits)

4n27A / Q2YQG1 X-ray structure of brucella abortus rica (see paper)
    52% identity, 94% coverage of query (184 bits)

6iveA / Q5SH51 Molecular structure of a thermostable and a zinc ion binding gamma- class carbonic anhydrase (see paper)
    47% identity, 96% coverage of query (162 bits)

3vnpA / Q5KW03 Crystal structure of hypothetical protein (gk2848) from geobacillus kaustophilus
    45% identity, 95% coverage of query (162 bits)

CAG_GEOKA / Q5KW03 Carbonic anhydrase; Gamma-carbonic anhydrase; Cag; EC 4.2.1.1 from Geobacillus kaustophilus (strain HTA426) (see 2 papers)
    45% identity, 95% coverage of query (162 bits)

O59257 carbonic anhydrase (EC 4.2.1.1) from Pyrococcus horikoshii (see 2 papers)
2fkoA / O59257 Structure of ph1591 from pyrococcus horikoshii ot3 (see paper)
    46% identity, 94% coverage of query (150 bits)

1v3wA Structure of ferripyochelin binding protein from pyrococcus horikoshii ot3
    46% identity, 94% coverage of query (150 bits)

8e73G2 / A0A1S3U544 8e73G2 (see paper)
    40% identity, 91% coverage of query (135 bits)

6sc4B / A0A133ULQ3 Gamma-carbonic anhydrase from the haloarchaeon halobacterium sp. (see paper)
    36% identity, 97% coverage of query (129 bits)

7aqqz / Q9FWR5 Cryo-em structure of arabidopsis thaliana complex-i (membrane core) (see paper)
    36% identity, 91% coverage of query (127 bits)

GCA1_ARATH / Q9FWR5 Gamma carbonic anhydrase 1, mitochondrial; AtCA1; GAMMA CA1; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9FWR5 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    36% identity, 91% coverage of query (127 bits)

7a23p Plant mitochondrial respiratory complex i
    36% identity, 91% coverage of query (127 bits)

at1g47260 / Q9C6B3 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCA2_ARATH / Q9C6B3 Gamma carbonic anhydrase 2, mitochondrial; AtCA2; GAMMA CA2; Transcription factor APFI; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q9C6B3 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    35% identity, 91% coverage of query (126 bits)

7aqqy / Q9C6B3 Cryo-em structure of arabidopsis thaliana complex-i (membrane core) (see paper)
    35% identity, 91% coverage of query (125 bits)

8bpxy Cytochrome b-c1 complex subunit Rieske-1, mitochondrial
    35% identity, 91% coverage of query (125 bits)

8befy Cryo-em structure of the arabidopsis thaliana i+iii2 supercomplex (ci membrane core)
    35% identity, 91% coverage of query (125 bits)

7ar7y Cryo-em structure of arabidopsis thaliana complex-i (open conformation)
    35% identity, 91% coverage of query (125 bits)

YdbZ / b1400 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA thioesterase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
paaY / P77181 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA thioesterase from Escherichia coli (strain K12) (see 4 papers)
    41% identity, 91% coverage of query (124 bits)

3tioF / P0A9W9 Crystal structures of yrda from escherichia coli, a homologous protein of gamma-class carbonic anhydrase, show possible allosteric conformations (see paper)
    36% identity, 93% coverage of query (124 bits)

YrdA / b3279 hexapeptide repeats-containing protein YrdA from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    36% identity, 93% coverage of query (124 bits)

3ixcA / Q2GIS1 Crystal structure of hexapeptide transferase family protein from anaplasma phagocytophilum
    37% identity, 90% coverage of query (121 bits)

3r3rA / Q8ZLN3 Structure of the yrda ferripyochelin binding protein from salmonella enterica
    37% identity, 91% coverage of query (120 bits)

at5g66510 / Q94AU7 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCA3_ARATH / Q94AU7 Gamma carbonic anhydrase 3, mitochondrial; AtCA3; GAMMA CA3; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    36% identity, 91% coverage of query (120 bits)

8gppA Acinetobacter baumannii carbonic anhydrase paay
    34% identity, 91% coverage of query (97.8 bits)

8gpmA / A0A6F8THQ5 Acinetobacter baumannii carbonic anhydrase
    34% identity, 91% coverage of query (97.4 bits)

at5g63510 / Q9FMV1 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCAL1_ARATH / Q9FMV1 Gamma carbonic anhydrase-like 1, mitochondrial; AtCAL1; GAMMA CAL1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FMV1 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    33% identity, 90% coverage of query (93.2 bits)

at3g48680 / Q9SMN1 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCAL2_ARATH / Q9SMN1 Gamma carbonic anhydrase-like 2, mitochondrial; AtCAL2; GAMMA CAL2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9SMN1 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    33% identity, 90% coverage of query (92.0 bits)

8bpxx Cytochrome b-c1 complex subunit Rieske-1, mitochondrial
    33% identity, 90% coverage of query (92.0 bits)

CaiE / b0035 putative transferase CaiE from Escherichia coli K-12 substr. MG1655 (see 2 papers)
caiE / P39206 putative transferase CaiE from Escherichia coli (strain K12) (see paper)
CAIE_ECOLI / P39206 Carnitine operon protein CaiE from Escherichia coli (strain K12) (see paper)
    30% identity, 93% coverage of query (91.7 bits)

C3W4Q7 carbonic anhydrase (EC 4.2.1.1) from Methanosarcina thermophila (see paper)
    33% identity, 83% coverage of query (70.5 bits)

Build an alignment

Build an alignment for H281DRAFT_00501 and 30 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

K4N028 carbonic anhydrase (EC 4.2.1.1) from Serratia sp. ISTD04 (see paper)
    28% identity, 93% coverage of query (62.4 bits)

1qrlA / P40881 A closer look at the active site of gamma-carbonic anhydrases: high resolution crystallographic studies of the carbonic anhydrase from methanosarcina thermophila (see paper)
    30% identity, 74% coverage of query (58.2 bits)

CAH_METTT / P40881 Carbonic anhydrase; CA; Cam; EC 4.2.1.1 from Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1) (see 3 papers)
P40881 carbonic anhydrase (EC 4.2.1.1) from Methanosarcina thermophila (see 9 papers)
    30% identity, 74% coverage of query (57.8 bits)

1qq0A Cobalt substituted carbonic anhydrase from methanosarcina thermophila
    30% identity, 74% coverage of query (57.8 bits)

CCMM_SYNP2 / O30711 Carboxysome assembly protein CcmM; CcmM70; M70; Carbon dioxide concentrating mechanism protein CcmM from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
    29% identity, 72% coverage of query (57.0 bits)

CCMM_NOSS1 / Q8YYI3 Carboxysome assembly protein CcmM; CcmM58; M58; Carbon dioxide concentrating mechanism protein CcmM; Carbonic anhydrase; EC 4.2.1.1 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see 2 papers)
    27% identity, 74% coverage of query (55.5 bits)

4mzuB Crystal structure of fdtd, a bifunctional ketoisomerase/n- acetyltransferase from shewanella denitrificans
    27% identity, 79% coverage of query (52.4 bits)

3kwcA / Q8DKB5 Oxidized, active structure of the beta-carboxysomal gamma-carbonic anhydrase, ccmm (see paper)
    27% identity, 84% coverage of query (51.2 bits)

4mzuF / Q12KT8 Crystal structure of fdtd, a bifunctional ketoisomerase/n- acetyltransferase from shewanella denitrificans (see paper)
    26% identity, 79% coverage of query (51.2 bits)

fdtD / Q12KT8 bifunctional ketoisomerase / N-acetyltransferase FdtD subunit (EC 5.3.2.3; EC 2.3.1.197) from Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) (see paper)
    27% identity, 79% coverage of query (50.1 bits)

A9IH93 UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase (EC 2.3.1.201) from Bordetella petrii (see paper)
    28% identity, 79% coverage of query (46.2 bits)

3mqgC / A9IH93 Crystal structure of the 3-n-acetyl transferase wlbb from bordetella petrii in complex with acetyl-coa (see paper)
    28% identity, 79% coverage of query (46.2 bits)

3mqhA Crystal structure of the 3-n-acetyl transferase wlbb from bordetella petrii in complex with coa and udp-3-amino-2-acetamido-2,3-dideoxy glucuronic acid
    28% identity, 79% coverage of query (46.2 bits)

fdtC / Q6T1W7 dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose 3-N-acetyltransferase (EC 2.3.1.197) from Aneurinibacillus thermoaerophilus (see 2 papers)
FDTC_ANETH / Q6T1W7 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase; dTDP-D-Fucp3N acetylase; EC 2.3.1.197 from Aneurinibacillus thermoaerophilus (see paper)
Q6T1W7 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase (EC 2.3.1.197) from Aneurinibacillus thermoaerophilus (see paper)
    29% identity, 78% coverage of query (45.8 bits)

7o54A / Q03513 Crystal structure of the carbonic anhydrase-like domain of ccmm in complex with thE C-terminal 17 residues of ccaa from synechococcus elongatus (strain pcc 7942) (see paper)
    27% identity, 74% coverage of query (44.7 bits)

CCMM_SYNY3 / P72758 Carboxysome assembly protein CcmM; CcmM73; M73; Carbon dioxide concentrating mechanism protein CcmM from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
P72758 carbonic anhydrase (EC 4.2.1.1) from Synechocystis sp. PCC 6803 (see paper)
    22% identity, 89% coverage of query (43.9 bits)

CCMM_SYNE7 / Q03513 Carboxysome assembly protein CcmM; CcmM58; M58; Carbon dioxide concentrating mechanism protein CcmM; Carboxysome shell associated protein CcmM from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see 11 papers)
    27% identity, 74% coverage of query (43.9 bits)

3fscA Crystal structure of qdtc, the dtdp-3-amino-3,6-dideoxy-d-glucose n- acetyl transferase from thermoanaerobacterium thermosaccharolyticum in complex with coa and dtdp-3-amino-fucose
    27% identity, 81% coverage of query (42.4 bits)

3fs8A Crystal structure of qdtc, the dtdp-3-amino-3,6-dideoxy-d- glucose n-acetyl transferase from thermoanaerobacterium thermosaccharolyticum in complex with acetyl-coa
    27% identity, 81% coverage of query (42.4 bits)

3fsbA / Q6TFC6 Crystal structure of qdtc, the dtdp-3-amino-3,6-dideoxy-d-glucose n- acetyl transferase from thermoanaerobacterium thermosaccharolyticum in complex with coa and dtdp-3-amino-quinovose (see paper)
    27% identity, 81% coverage of query (42.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory