Searching for up to 100 curated homologs for H281DRAFT_00641 H281DRAFT_00641 Uncharacterized conserved protein, DUF849 family (312 a.a.)
Found high-coverage hits (≥70%) to 21 curated proteins.
Removed hits that are identical to the query, leaving 20
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3e02A / Q13I95 Crystal structure of a duf849 family protein (bxe_c0271) from burkholderia xenovorans lb400 at 1.90 a resolution
63% identity, 99% coverage of query (405 bits)
3e49A / Q13GE9 Crystal structure of a prokaryotic domain of unknown function (duf849) with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb400 at 1.75 a resolution
60% identity, 99% coverage of query (393 bits)
PS417_07250 2-deoxy-3-keto-D-ribonoate cleavage enzyme from Pseudomonas simiae WCS417
57% identity, 99% coverage of query (341 bits)
3lotD / O29058 Crystal structure of protein of unknown function (np_070038.1) from archaeoglobus fulgidus at 1.89 a resolution
50% identity, 98% coverage of query (326 bits)
kce / Q8RHX2 3-keto,5-aminohexanoate cleavage enzyme subunit (EC 2.3.1.247) from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see 2 papers)
KCE_FUSNN / Q8RHX2 3-keto-5-aminohexanoate cleavage enzyme; EC 2.3.1.247 from Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) (see 2 papers)
Q8RHX2 3-keto-5-aminohexanoate cleavage enzyme (EC 2.3.1.247) from Fusobacterium nucleatum subsp. nucleatum (see 2 papers)
35% identity, 96% coverage of query (162 bits)
KCE_CLOAI / B0VHH0 3-keto-5-aminohexanoate cleavage enzyme; EC 2.3.1.247 from Cloacimonas acidaminovorans (strain Evry) (see paper)
B0VHH0 3-keto-5-aminohexanoate cleavage enzyme (EC 2.3.1.247) from Candidatus Cloacimonas acidaminovorans (see paper)
kce / CAO80785.1 3-keto-5-aminohexanoate cleavage enzyme from Candidatus Cloacimonas acidaminovorans str. Evry (see paper)
33% identity, 95% coverage of query (151 bits)
2y7dD / B0VHH0 Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from candidatus cloacamonas acidaminovorans (orthorombic form) (see paper)
33% identity, 96% coverage of query (151 bits)
2y7fD Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
33% identity, 95% coverage of query (151 bits)
2y7fA Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
33% identity, 95% coverage of query (151 bits)
2y7gA Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (kce) from c. Cloacamonas acidaminovorans in complex with the product acetoacetate
33% identity, 95% coverage of query (151 bits)
Pf6N2E2_4692 dehydrocarnitine cleavage enzyme (EC 2.3.1.-) from Pseudomonas fluorescens FW300-N2E2
34% identity, 96% coverage of query (147 bits)
cdhC / Q9HTH7 3-dehydrocarnitine cleavage enzyme from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
33% identity, 96% coverage of query (144 bits)
Build an alignment for H281DRAFT_00641 and 12 homologs with ≥ 30% identity
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3no5E / Q471D6 Crystal structure of a pfam duf849 domain containing protein (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution
29% identity, 96% coverage of query (108 bits)
3fa5A / A1B7S1 Crystal structure of a duf849 family protein (pden_3495) from paracoccus denitrificans pd1222 at 1.90 a resolution
27% identity, 96% coverage of query (99.0 bits)
3chvA / Q6SJB6 Crystal structure of a prokaryotic domain of unknown function (duf849) member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a resolution
24% identity, 97% coverage of query (89.0 bits)
5zmuD / F1LJ99 Crystal structure of a cis-epoxysuccinate hydrolase producing d(-)- tartaric acids (see paper)
27% identity, 89% coverage of query (80.1 bits)
5zmyA Crystal structure of a cis-epoxysuccinate hydrolase producing d(-)- tartaric acids
27% identity, 89% coverage of query (77.0 bits)
4nnbA Binary complex of obca with oxaloacetate
25% identity, 95% coverage of query (48.9 bits)
4nncA Ternary complex of obca with c4-coa adduct and oxalate
25% identity, 95% coverage of query (48.5 bits)
4nnaA / C5AJX5 Apo structure of obca (see paper)
25% identity, 95% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory