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Searching for up to 100 curated homologs for H281DRAFT_01221 FitnessBrowser__Burk376:H281DRAFT_01221 (338 a.a.)

Found high-coverage hits (≥70%) to 46 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.2.20 / G4FGN4 Putative beta-xyloside ABC transporter, permease component, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    37% identity, 86% coverage of query (158 bits)

TC 3.A.1.2.9 / Q7BSH3 RhaP, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii)
    36% identity, 95% coverage of query (157 bits)

LSRD_SALTY / Q8ZKQ2 Autoinducer 2 import system permease protein LsrD; AI-2 import system permease protein LsrD from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    31% identity, 92% coverage of query (154 bits)

TC 3.A.1.2.13 / A6VKS9 RbsC, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    36% identity, 89% coverage of query (152 bits)

YdeZ / b1515 Autoinducer-2 ABC transporter membrane subunit LsrD (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lsrD / P0AFS1 Autoinducer-2 ABC transporter membrane subunit LsrD (EC 7.6.2.13) from Escherichia coli (strain K12) (see 2 papers)
LSRD_ECOLI / P0AFS1 Autoinducer 2 import system permease protein LsrD; AI-2 import system permease protein LsrD from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.8 / P0AFS1 LsrD(M)AKA Inner membrane ABC transporter permease protein ydeZ, component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 6 papers)
lsrD autoinducer 2 ABC transporter, permease protein LsrD from Escherichia coli K12 (see paper)
    34% identity, 94% coverage of query (147 bits)

YphD / b2546 putative ABC transporter membrane subunit YphD from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    36% identity, 91% coverage of query (146 bits)

Pf6N2E2_5970 ABC transporter for D-galactose/L-arabinose, permease component from Pseudomonas fluorescens FW300-N2E2
    32% identity, 95% coverage of query (145 bits)

BPHYT_RS16925 D-galactose ABC transporter, permease component from Burkholderia phytofirmans PsJN
    31% identity, 95% coverage of query (144 bits)

Pf1N1B4_409 ABC transporter for D-galactose/L-arabinose, permease component from Pseudomonas fluorescens FW300-N1B4
    32% identity, 95% coverage of query (142 bits)

HSERO_RS03645 D-mannose ABC transporter, permease component from Herbaspirillum seropedicae SmR1
    36% identity, 84% coverage of query (141 bits)

eryF / Q2YIY3 putative erythritol ABC transporter membrane protein from Brucella abortus (strain 2308) (see 3 papers)
    33% identity, 93% coverage of query (139 bits)

HSERO_RS05255 ABC transporter for L-fucose, permease component from Herbaspirillum seropedicae SmR1
    33% identity, 92% coverage of query (139 bits)

TC 3.A.1.2.19 / Q9X050 ABC-type transporter, integral membrane subunit, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    33% identity, 87% coverage of query (137 bits)

AraH / b4460 arabinose ABC transporter membrane subunit (EC 7.5.2.13; EC 7.5.2.12) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
araH / P0AE26 arabinose ABC transporter membrane subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
ARAH_ECOLI / P0AE26 L-arabinose transport system permease protein AraH from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.2 / P0AE26 L-arabinose transport system permease protein araH aka b4460, component of Arabinose porter from Escherichia coli (see 7 papers)
araH / GB|AAN43497.1 L-arabinose ABC transporter, permease protein AraH from Escherichia coli K12 (see 2 papers)
    33% identity, 91% coverage of query (137 bits)

PS417_12060 xylitol ABC transporter, permease component from Pseudomonas simiae WCS417
    34% identity, 91% coverage of query (137 bits)

RbsC / b3750 ribose ABC transporter membrane subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsC / P0AGI1 ribose ABC transporter membrane subunit from Escherichia coli (strain K12) (see 4 papers)
RBSC_ECOLI / P0AGI1 Ribose import permease protein RbsC from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.2.1 / P0AGI1 Ribose transport system permease protein RbsC aka B3750, component of Ribose porter from Escherichia coli (see 6 papers)
    35% identity, 91% coverage of query (136 bits)

TC 3.A.1.2.16 / Q1M4Q8 Erythritol permease, component of ABC transporter, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    33% identity, 86% coverage of query (135 bits)

BPHYT_RS34240 ABC transporter for L-rhamnose/L-fucose/xylitol, permease component from Burkholderia phytofirmans PsJN
    32% identity, 85% coverage of query (133 bits)

TC 3.A.1.2.18 / Q9WXW7 ABC-type transporter, integral membrane subunit, component of Xylose porter (Nanavati et al. 2006). Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    32% identity, 78% coverage of query (130 bits)

PS417_11895 Inositol transport system permease protein from Pseudomonas simiae WCS417
    30% identity, 98% coverage of query (125 bits)

AO353_21390 m-Inositol ABC transporter, permease component (iatP) from Pseudomonas fluorescens FW300-N2E3
    30% identity, 98% coverage of query (120 bits)

HSERO_RS11490 D-ribose ABC transporter, permease component RbsC from Herbaspirillum seropedicae SmR1
    33% identity, 87% coverage of query (119 bits)

RR42_RS03365 fructose ABC transporter, permease component (FrcC) from Cupriavidus basilensis FW507-4G11
    33% identity, 91% coverage of query (118 bits)

AlsC / b4086 D-allose ABC transporter membrane subunit (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see paper)
AlsC / P32720 D-allose ABC transporter membrane subunit (EC 7.5.2.8) from Escherichia coli (strain K12) (see paper)
ALSC_ECOLI / P32720 D-allose transport system permease protein AlsC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.6 / P32720 AlsC aka B4086, component of D-allose porter from Escherichia coli (see 6 papers)
    30% identity, 90% coverage of query (118 bits)

FRCC_RHIML / Q9F9B1 Fructose import permease protein FrcC from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 3.A.1.2.7 / Q9F9B1 FrcC, component of Fructose/mannose/ribose porter from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
    31% identity, 80% coverage of query (118 bits)

PS417_18395 D-ribose ABC transporter, permease component RbsC from Pseudomonas simiae WCS417
    33% identity, 88% coverage of query (113 bits)

Pf1N1B4_6033 D-ribose ABC transporter, permease component RbsC from Pseudomonas fluorescens FW300-N1B4
    32% identity, 88% coverage of query (111 bits)

Build an alignment

Build an alignment for H281DRAFT_01221 and 27 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

XylH / b3568 xylose ABC transporter membrane subunit (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
XylH / P0AGI4 xylose ABC transporter membrane subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.4 / P0AGI4 Xylose transport system permease protein XylH aka B3568, component of Xylose porter from Escherichia coli (see 4 papers)
xylH / RF|NP_418025 D-xylose ABC transporter, permease protein from Escherichia coli K12 (see 7 papers)
    28% identity, 95% coverage of query (109 bits)

YjfF / b4231 galactofuranose ABC transporter putative membrane subunit YjtF (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
YjfF / P37772 galactofuranose ABC transporter putative membrane subunit YjtF (EC 7.5.2.9) from Escherichia coli (strain K12) (see 3 papers)
YJFF_ECOLI / P37772 Inner membrane ABC transporter permease protein YjfF from Escherichia coli (strain K12) (see paper)
    30% identity, 88% coverage of query (108 bits)

TC 3.A.1.2.21 / B8H230 Inositol ABC transport system, permease protein IatP, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    31% identity, 84% coverage of query (108 bits)

YdeY / b1514 Autoinducer-2 ABC transporter membrane subunit LsrC (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lsrC / P77672 Autoinducer-2 ABC transporter membrane subunit LsrC (EC 7.6.2.13) from Escherichia coli (strain K12) (see 2 papers)
LSRC_ECOLI / P77672 Autoinducer 2 import system permease protein LsrC; AI-2 import system permease protein LsrC from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.8 / P77672 LsrC(M), component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 6 papers)
lsrC / RF|NP_416031.1 autoinducer 2 ABC transporter, permease protein LsrC from Escherichia coli (see paper)
    31% identity, 87% coverage of query (105 bits)

TC 3.A.1.2.11 / Q92WK1 EryF aka RB0338, component of The erythritol permease, EryEFG (Geddes et al., 2010) (probably orthologous to 3.A.1.2.16) from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    32% identity, 81% coverage of query (102 bits)

TC 3.A.1.2.5 / O05177 GguB aka ATU2346 aka AGR_C_4262, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium radiobacter (see paper)
    31% identity, 80% coverage of query (102 bits)

XYLH_SULAC / Q4J711 Xylose/arabinose import permease protein XylH from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J711 ABC-type D-xylose/L-arabinose transporter (subunit 2/2) (EC 7.5.2.13) from Sulfolobus acidocaldarius (see paper)
    28% identity, 88% coverage of query (99.8 bits)

LSRC_SALTY / Q8ZKQ3 Autoinducer 2 import system permease protein LsrC; AI-2 import system permease protein LsrC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    30% identity, 87% coverage of query (99.4 bits)

PGA1_c07310 Inositol transport system permease protein from Phaeobacter inhibens BS107
    29% identity, 82% coverage of query (94.0 bits)

Shewana3_2076 L-arabinose ABC transporter, permease component 2 AraZ from Shewanella sp. ANA-3
    33% identity, 79% coverage of query (93.6 bits)

YtfT / b4230 galactofuranose ABC transporter putative membrane subunit YtfT (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
YtfT / P39328 galactofuranose ABC transporter putative membrane subunit YtfT (EC 7.5.2.9) from Escherichia coli (strain K12) (see 2 papers)
YTFT_ECOLI / P39328 Galactofuranose transporter permease protein YtfT from Escherichia coli (strain K12) (see paper)
    33% identity, 74% coverage of query (92.0 bits)

FRUG_BIFLO / Q8G845 Fructose import permease protein FruG from Bifidobacterium longum (strain NCC 2705) (see paper)
    32% identity, 88% coverage of query (90.9 bits)

Shewana3_2075 L-arabinose ABC transporter, permease component 1 AraW from Shewanella sp. ANA-3
    29% identity, 82% coverage of query (89.7 bits)

H281DRAFT_01112 deoxynucleoside transporter, permease component 2 from Paraburkholderia bryophila 376MFSha3.1
    31% identity, 90% coverage of query (87.8 bits)

H281DRAFT_01115 deoxynucleoside transporter, permease component 1 from Paraburkholderia bryophila 376MFSha3.1
    32% identity, 75% coverage of query (86.7 bits)

TC 3.A.1.2.24 / O50505 Probable ABC-type transmembrane transport protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    26% identity, 95% coverage of query (80.5 bits)

FRUF_BIFLO / Q8G846 Fructose import permease protein FruF from Bifidobacterium longum (strain NCC 2705) (see paper)
    28% identity, 83% coverage of query (69.7 bits)

TC 3.A.1.2.26 / A6LW12 Monosaccharide-transporting ATPase, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
    25% identity, 81% coverage of query (62.4 bits)

TC 3.A.1.2.10 / O83342 Ribose/galactose ABC transporter, permease protein aka RbsC-1, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see paper)
    29% identity, 77% coverage of query (60.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory