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Searching for up to 100 curated homologs for H281DRAFT_01715 H281DRAFT_01715 sulfate permease, SulP family (553 a.a.)

Found high-coverage hits (≥70%) to 41 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BICA_SYNP2 / Q14SY0 Bicarbonate transporter BicA from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) (see 2 papers)
TC 2.A.53.3.3 / Q14SY0 12 TMS Na+:bicarbonate symporter, BicA (Price et al., 2004; Shelden et al., 2010) (low affinity but high efficiency) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see paper)
    40% identity, 95% coverage of query (343 bits)

BICA_SYNY3 / Q55415 Bicarbonate transporter BicA from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    40% identity, 95% coverage of query (334 bits)

TC 2.A.53.3.2 / Q7U617 Bicarbonate:Na+ symporter, BicA (see paper)
    39% identity, 90% coverage of query (273 bits)

TC 2.A.53.3.13 / Q1J2S8 Fumarate (Na+-independent anion) transporter, SLC26dg of 499 aas and 14 TMSs from Deinococcus geothermalis (strain DSM 11300)
    31% identity, 91% coverage of query (204 bits)

Build an alignment

Build an alignment for H281DRAFT_01715 and 4 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 2.A.53.3.1 / O07488 Sulfate permease from Yersinia enterocolitica (see paper)
    29% identity, 91% coverage of query (204 bits)

TC 2.A.53.3.9 / A1JRS3 SulP homologue. The low resolution structure is available from Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) (see paper)
    31% identity, 87% coverage of query (199 bits)

5da0A / Q1J2S8 Structure of the the slc26 transporter slc26dg in complex with a nanobody (see paper)
    31% identity, 91% coverage of query (198 bits)

DauA / b1206 aerobic C4-dicarboxylate transporter DauA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
DauA / P0AFR2 aerobic C4-dicarboxylate transporter DauA from Escherichia coli (strain K12) (see 9 papers)
DAUA_ECOLI / P0AFR2 C4-dicarboxylic acid transporter DauA; Dicarboxylic acid uptake system A from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.53.3.11 / P0AFR2 Bicarbonate transporter, DauA (YchM). Also transports dicarboxylic acids including fumarate, aspartate and succinate, and is therefore designated the dicarboxylic acid uptake system A (DauA) (Karinou et al. 2013) It is the only succinate uptake porter at acidic pHs. The STAS domain forms a complex with the acyl carrier protein, ACP and malonyl-ACP, and the complex has been determined by x-ray crystallography (PDB# 3NY7) from Escherichia coli (strain K12)
    32% identity, 95% coverage of query (179 bits)

TC 2.A.53.3.5 / F5R8F2 SulP homologue with fused C-terminal STAS/CAP-ED domains (function unknown COG0659) from Methyloversatilis universalis FAM5
    31% identity, 87% coverage of query (156 bits)

Y1739_MYCTU / P9WGF7 Probable sulfate transporter Rv1739c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 2.A.53.4.2 / P71997 Sulfate transporter, Rv1739c from Mycobacterium tuberculosis
    27% identity, 91% coverage of query (146 bits)

SUT41_ARATH / Q9FY46 Sulfate transporter 4.1, chloroplastic; AST82 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    25% identity, 86% coverage of query (141 bits)

7lhvA / Q9FY46 Structure of arabidopsis thaliana sulfate transporter atsultr4;1 (see paper)
    25% identity, 86% coverage of query (140 bits)

7v74A Thermostabilized human prestin in complex with sulfate
    27% identity, 91% coverage of query (138 bits)

P96878 carbonic anhydrase (EC 4.2.1.1) from Mycobacterium tuberculosis (see paper)
TC 2.A.53.3.12 / P96878 A bicarbonate transporter fused to a carbonic anhydrase, Rv3273 from Mycobacterium tuberculosis
    31% identity, 73% coverage of query (137 bits)

7v75A Thermostabilized human prestin in complex with salicylate (see paper)
    26% identity, 91% coverage of query (134 bits)

TC 2.A.53.4.1 / P72770 Sulfate transporter (see paper)
    26% identity, 91% coverage of query (134 bits)

TC 2.A.53.3.8 / Q8F8H7 SulP homologue with fused C-terminal carbonic anhydrase domain, probable bicarbonate uptake transporter from Leptospira interrogans (see paper)
    27% identity, 71% coverage of query (129 bits)

SULT2_CHLRE / A8J6J0 Proton/sulfate cotransporter 2 from Chlamydomonas reinhardtii (Chlamydomonas smithii) (see 2 papers)
TC 2.A.53.1.8 / A8J6J0 The proton:sulfate symporter, SulP from Chlamydomonas reinhardtii (see paper)
    24% identity, 91% coverage of query (122 bits)

TC 2.A.53.1.12 / Q0P7I2 Symbiotic sulfate transporter-1, SST1 of 645 aas from Lotus japonicus
    22% identity, 91% coverage of query (110 bits)

bst3.1 / CAE46442.1 sulphate transporter from Brassica napus (see paper)
    21% identity, 86% coverage of query (103 bits)

SHST2 / CAA57711.1 high affinity sulphate transporter from Stylosanthes hamata (see paper)
    22% identity, 88% coverage of query (100 bits)

ST1 / CAA65291.1 high affinity sulphate transporter from Hordeum vulgare (see paper)
    22% identity, 88% coverage of query (100 bits)

SUT21_ARATH / O04722 Sulfate transporter 2.1; AST68 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    25% identity, 71% coverage of query (100 bits)

S26A7_MOUSE / Q8R2Z3 Anion exchange transporter; Solute carrier family 26 member 7 from Mus musculus (Mouse) (see 9 papers)
    23% identity, 95% coverage of query (100 bits)

TC 2.A.53.1.4 / P53393 Low-affinity sulfate:H+ symporter, Sut3 from Stylosanthes hamata (see paper)
    23% identity, 91% coverage of query (96.7 bits)

sB sulfate permease from Emericella nidulans (see 3 papers)
    25% identity, 71% coverage of query (95.5 bits)

SULH3_SCHPO / O59782 Probable sulfate permease C320.05 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    24% identity, 80% coverage of query (95.1 bits)

TC 2.A.53.1.3 / P53391 The molybdate (high affinity)/Sulfate (lower affinity) transporter, ShsT1 from Stylosanthes hamata (see paper)
SHST1 / CAA57710.1 high affinity sulphate transporter from Stylosanthes hamata (see paper)
    22% identity, 88% coverage of query (92.0 bits)

TC 2.A.53.3.6 / Q5N2Y3 Nitrate transporter with fused C-terminal STAS/CAP-ED domain, LtnT (see paper)
    26% identity, 79% coverage of query (91.7 bits)

S2611_CAVPO / G3C7W6 Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11 from Cavia porcellus (Guinea pig) (see paper)
TC 2.A.53.1.9 / G3C7W6 Slc26a11 Cl-/oxalate or sulfate (but not bicarbonate) exchanger from Cavia porcellus (see paper)
    25% identity, 95% coverage of query (91.7 bits)

S26A2_MOUSE / Q62273 Sulfate transporter; Diastrophic dysplasia protein homolog; ST-OB; Solute carrier family 26 member 2 from Mus musculus (Mouse) (see 4 papers)
    21% identity, 91% coverage of query (85.9 bits)

S26A5_MERUN / Q9JKQ2 Prestin; Solute carrier family 26 member 5 from Meriones unguiculatus (Mongolian jird) (Gerbillus unguiculatus) (see 4 papers)
    21% identity, 83% coverage of query (84.7 bits)

SUT11_ARATH / Q9SAY1 Sulfate transporter 1.1; AST101; High-affinity sulfate transporter 1; Hst1At from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
TC 2.A.53.1.7 / Q9SAY1 High affinity sulfate transporter, Sultr1.1 regulated differently from Sultr1.2 (2.A.53.1.6) from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    23% identity, 88% coverage of query (84.7 bits)

S26A5_HUMAN / P58743 Prestin; Solute carrier family 26 member 5 from Homo sapiens (Human) (see 2 papers)
TC 2.A.53.2.19 / P58743 Prestin (Solute carrier family 26 member 5) from Homo sapiens (see 3 papers)
    22% identity, 81% coverage of query (83.6 bits)

7lguA / P58743 Structure of human prestin in the presence of nacl (see paper)
    22% identity, 81% coverage of query (83.6 bits)

SUT13_ARATH / Q9FEP7 Sulfate transporter 1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    24% identity, 88% coverage of query (83.6 bits)

S26A1_RAT / P45380 Sulfate anion transporter 1; SAT-1; Canalicular sulfate transporter; Solute carrier family 26 member 1; Sulfate/carbonate antiporter from Rattus norvegicus (Rat) (see 7 papers)
TC 2.A.53.2.2 / P45380 Canicular sulfate:HCO3- antiporter (Slc26a1) from Rattus norvegicus (Rat) (see paper)
    24% identity, 80% coverage of query (79.0 bits)

S26A1_MOUSE / P58735 Sulfate anion transporter 1; SAT-1; Solute carrier family 26 member 1 from Mus musculus (Mouse) (see 4 papers)
    23% identity, 80% coverage of query (78.6 bits)

SUT12_ARATH / Q9MAX3 Sulfate transporter 1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
TC 2.A.53.1.6 / Q9MAX3 The sulfate transporter, Sultr1.2 with C-terminal STAS domain that is required both for activity and biogenesis/stability (Shibagaki and Grossman, 2006). It physically interacts with 0-acetylserine (thiol)lyase (cysteine synthetase) via its STAS domain. This interaction stimulates the activity of from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
SULTR1;2 / RF|NP_849899.1 sulfate transporter 1.2 from Arabidopsis thaliana (see paper)
    22% identity, 88% coverage of query (76.3 bits)

TC 2.A.53.2.20 / Q94225 Sulfate permease family protein 3, Sulp-3 from Caenorhabditis elegans (see 2 papers)
    24% identity, 80% coverage of query (75.5 bits)

S26A1_HUMAN / Q9H2B4 Sulfate anion transporter 1; SAT-1; Solute carrier family 26 member 1 from Homo sapiens (Human) (see 3 papers)
TC 2.A.53.2.16 / Q9H2B4 Sulfate anion transporter 1 (SAT-1 or SAT1) (Solute carrier family 26 member 1); anion exchanger.  Transports chloride, sulfate, bicarbonate and oxalate (Regeer et al. 2003; Lee et al. 2003).  The mouse and rat orthologues have the same specificities and functions. Loss in mice  is associated with hyperoxalurea and calcium oxalate kidney stones, and specific mutations when heterozygous in humans cause urolithiasis (Dawson et al. 2013).  When homozygous, they can cause severe nephrocalcinosis from Homo sapiens (see 5 papers)
    23% identity, 80% coverage of query (74.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory