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Searching for up to 100 curated homologs for H281DRAFT_02118 FitnessBrowser__Burk376:H281DRAFT_02118 (303 a.a.)

Found high-coverage hits (≥70%) to 76 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

BPHYT_RS02045 Fructokinase (EC 2.7.1.4) from Burkholderia phytofirmans PsJN
    94% identity, 99% coverage of query (527 bits)

AO356_00035 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2C3
    50% identity, 98% coverage of query (272 bits)

Pf6N2E2_1965 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E2
    50% identity, 98% coverage of query (270 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    33% identity, 90% coverage of query (110 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    33% identity, 90% coverage of query (110 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    33% identity, 90% coverage of query (109 bits)

4wjmA / Q2YNY7 Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
    31% identity, 92% coverage of query (102 bits)

scrK / P26420 fructokinase (EC 2.7.1.4) from Klebsiella pneumoniae (see paper)
SCRK_KLEPN / P26420 Fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / GB|CAA43322.1 fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / CAA43322.1 fructokinase from Klebsiella pneumoniae (see paper)
    34% identity, 82% coverage of query (101 bits)

PfGW456L13_3036 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens GW456-L13
    34% identity, 86% coverage of query (99.8 bits)

Build an alignment

Build an alignment for H281DRAFT_02118 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    29% identity, 91% coverage of query (99.4 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    30% identity, 95% coverage of query (99.4 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    31% identity, 91% coverage of query (98.6 bits)

A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
    31% identity, 91% coverage of query (98.2 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    28% identity, 93% coverage of query (98.2 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    30% identity, 97% coverage of query (97.1 bits)

AO353_25910 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E3
    34% identity, 86% coverage of query (96.7 bits)

5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
    30% identity, 91% coverage of query (95.5 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    34% identity, 85% coverage of query (92.0 bits)

scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    31% identity, 91% coverage of query (91.3 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    24% identity, 96% coverage of query (89.4 bits)

frk / GB|AAB52373.1 fructokinase; EC 2.7.1.4 from Rhizobium leguminosarum bv. trifolii (see paper)
    33% identity, 82% coverage of query (88.2 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    29% identity, 86% coverage of query (87.8 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    30% identity, 96% coverage of query (85.9 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    28% identity, 92% coverage of query (85.1 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    29% identity, 100% coverage of query (85.1 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    29% identity, 97% coverage of query (84.0 bits)

Sama_0561 Fructokinase (EC 2.7.1.4) from Shewanella amazonensis SB2B
    28% identity, 91% coverage of query (82.8 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    30% identity, 97% coverage of query (82.4 bits)

scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
    27% identity, 94% coverage of query (81.6 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    30% identity, 97% coverage of query (81.6 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    29% identity, 93% coverage of query (81.3 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    30% identity, 97% coverage of query (81.3 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    28% identity, 95% coverage of query (80.5 bits)

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    31% identity, 89% coverage of query (78.2 bits)

1v1aA / Q53W83 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
    31% identity, 89% coverage of query (77.8 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    29% identity, 96% coverage of query (77.0 bits)

1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp
    31% identity, 89% coverage of query (76.6 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    29% identity, 97% coverage of query (76.3 bits)

3ih0A / O59128 Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
    25% identity, 95% coverage of query (75.5 bits)

3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
    25% identity, 95% coverage of query (75.5 bits)

N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
    32% identity, 89% coverage of query (75.1 bits)

CCNA_01356 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Caulobacter crescentus NA1000
iolC-DUF2090 / A0A0H3C6B4 bifunctional 5-dehydro-2-deoxygluconokinase/5-dehydro-2-deoxyphosphogluconate aldolase (EC 2.7.1.92; EC 4.1.2.29) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 3 papers)
    27% identity, 80% coverage of query (73.9 bits)

Shewana3_0069 Fructokinase (EC 2.7.1.4) from Shewanella sp. ANA-3
    25% identity, 96% coverage of query (73.6 bits)

BPHYT_RS13910 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Burkholderia phytofirmans PsJN
    27% identity, 75% coverage of query (69.7 bits)

3lkiB / Q87CC0 Crystal structure of fructokinase with bound atp from xylella fastidiosa
    31% identity, 91% coverage of query (67.8 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    25% identity, 88% coverage of query (64.3 bits)

HSERO_RS12125 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Herbaspirillum seropedicae SmR1
    28% identity, 86% coverage of query (62.0 bits)

BWI76_RS03085 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Klebsiella michiganensis M5al
    25% identity, 86% coverage of query (61.6 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    26% identity, 89% coverage of query (60.8 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    31% identity, 91% coverage of query (58.5 bits)

PS417_11850 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas simiae WCS417
    27% identity, 86% coverage of query (56.6 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    25% identity, 92% coverage of query (54.7 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    28% identity, 79% coverage of query (54.3 bits)

Atu3166 / A9CES5 tagatose kinase (EC 2.7.1.101) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
TAGK_AGRFC / A9CES5 Tagatose kinase; EC 2.7.1.101 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
    26% identity, 80% coverage of query (54.3 bits)

PfkB / b1723 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
pfkB / P06999 6-phosphofructokinase 2 (EC 2.7.1.11; EC 2.7.1.144) from Escherichia coli (strain K12) (see 40 papers)
PFKB_ECOLI / P06999 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; 6-phosphofructokinase isozyme II; Phosphohexokinase 2; EC 2.7.1.11 from Escherichia coli (strain K12) (see 4 papers)
P06999 6-phosphofructokinase (EC 2.7.1.11) from Escherichia coli (see 2 papers)
3n1cA / P06999 Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate (see paper)
    27% identity, 88% coverage of query (54.3 bits)

3uqdB Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    27% identity, 88% coverage of query (54.3 bits)

3uqdA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products
    27% identity, 88% coverage of query (54.3 bits)

AO353_21335 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2E3
    25% identity, 86% coverage of query (53.9 bits)

Q4KD57 2-ketogluconokinase (EC 2.7.1.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    30% identity, 78% coverage of query (53.5 bits)

Pf6N2E2_512 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2E2
    27% identity, 86% coverage of query (53.1 bits)

3cqdA Structure of the tetrameric inhibited form of phosphofructokinase-2 from escherichia coli
    27% identity, 85% coverage of query (53.1 bits)

C4M2I2 fructokinase (EC 2.7.1.4) from Entamoeba histolytica (see paper)
    21% identity, 83% coverage of query (52.4 bits)

SM_b21374 tagatose kinase (EC 2.7.1.101) from Sinorhizobium meliloti 1021
    27% identity, 92% coverage of query (52.4 bits)

Ac3H11_3034 Fructokinase (EC 2.7.1.4) from Acidovorax sp. GW101-3H11
    29% identity, 89% coverage of query (52.0 bits)

3uqeA Crystal structure of the phosphofructokinase-2 mutant y23d from escherichia coli
    27% identity, 85% coverage of query (52.0 bits)

YhjI / b3526 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178; EC 2.7.1.45) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
kdgK / P37647 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178) from Escherichia coli (strain K12) (see 4 papers)
KDGK_ECOLI / P37647 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain K12) (see paper)
    26% identity, 83% coverage of query (51.6 bits)

KDGK_ECOLW / E0J5J4 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W) (see paper)
    26% identity, 83% coverage of query (51.6 bits)

Fpk / b2168 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
fruK / P0AEW9 1-phosphofructokinase (EC 2.7.1.56) from Escherichia coli (strain K12) (see 8 papers)
K1PF_ECOLI / P0AEW9 1-phosphofructokinase; Fructose 1-phosphate kinase; Fru1PK; EC 2.7.1.56 from Escherichia coli (strain K12) (see paper)
fruK / RF|NP_416673 1-phosphofructokinase from Escherichia coli K12 (see 2 papers)
    27% identity, 76% coverage of query (51.6 bits)

fraD / Q8ZLD1 N-(1-deoxy-D-fructos-1-yl)-L-aspartate kinase from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    22% identity, 77% coverage of query (51.6 bits)

kdgK / P45416 2-dehydro-3-deoxy-D-gluconate kinase (EC 2.7.1.178) from Dickeya dadantii (strain 3937) (see 2 papers)
KDGK_DICD3 / P45416 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    26% identity, 81% coverage of query (50.8 bits)

SMc01165 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Sinorhizobium meliloti 1021
    25% identity, 89% coverage of query (50.1 bits)

6znxC / A0A0B0SD75 Ribokinase from thermus species
    30% identity, 95% coverage of query (49.7 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 76% coverage of query (48.1 bits)

SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
    27% identity, 93% coverage of query (48.1 bits)

TK2029 / Q5JDG9 α-D-ribose-1-phosphate 5-kinase (ADP) (EC 2.7.1.212) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
R1PK_THEKO / Q5JDG9 ADP-dependent ribose-1-phosphate kinase; ADP-R1P kinase; ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase; Alpha-D-ribose-1-phosphate 5-kinase (ADP); EC 2.7.1.212 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    22% identity, 77% coverage of query (45.4 bits)

2f02A / Q833W9 Crystal structure of lacc from enterococcus faecalis in complex with atp
    24% identity, 86% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory