Sites on a Tree

 

Searching for up to 100 curated homologs for H281DRAFT_02540 FitnessBrowser__Burk376:H281DRAFT_02540 (200 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

leuD / BAC65258.1 3-isopropylmalate dehydratase small subunit from Burkholderia multivorans (see paper)
    44% identity, 96% coverage of query (180 bits)

leuD / Q8F4E5 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) (see paper)
    41% identity, 97% coverage of query (160 bits)

O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    42% identity, 99% coverage of query (159 bits)

LEUD_RHIJ3 / Q1MA52 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    41% identity, 96% coverage of query (155 bits)

AN5886 alpha isopropylmalate isomerase (Eurofung) from Emericella nidulans (see paper)
    40% identity, 96% coverage of query (139 bits)

hbzJ / Q0QFQ6 maleate hydratase small subunit (EC 4.2.1.31) from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ6 maleate hydratase (subunit 1/2) (EC 4.2.1.31) from Pseudomonas alcaligenes (see paper)
    35% identity, 97% coverage of query (136 bits)

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    40% identity, 91% coverage of query (135 bits)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    36% identity, 99% coverage of query (131 bits)

LeuD / b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
leuD / P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12) (see 4 papers)
    39% identity, 91% coverage of query (129 bits)

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534) (see paper)
    37% identity, 95% coverage of query (119 bits)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis (see paper)
    40% identity, 95% coverage of query (118 bits)

P9WK95 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    40% identity, 95% coverage of query (118 bits)

leu1 / CAB99455.1 3-isopropylmalate dehydratase, partial from Yarrowia lipolytica (see paper)
    38% identity, 83% coverage of query (107 bits)

AMT8_ALTAL / C9K7B9 Aconitase AMT8; AM-toxin biosynthesis protein 8; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    38% identity, 72% coverage of query (78.6 bits)

AMT82_ALTAL / C9K7I3 Aconitase AMT8-2; AM-toxin biosynthesis protein 8-2; EC 4.2.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
    37% identity, 72% coverage of query (72.8 bits)

HtyD / K0E2G4 2-(4-hydroxybenzyl)-malate isomerase from Aspergillus rugulosus (see paper)
HTYD_ASPRU / K0E2G4 Aconitase htyD; L-homotyrosine biosynthetic cluster protein D; EC 4.2.1.- from Aspergillus rugulosus (Emericella rugulosa) (see paper)
    35% identity, 79% coverage of query (70.5 bits)

ACON3_ASPFU / Q4WBR0 Putative aconitate hydratase; Aconitase 3; EC 4.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
    32% identity, 76% coverage of query (68.9 bits)

dmdB / Q0QLE1 dimethylmaleate hydratase subunit B (EC 4.2.1.85) from Eubacterium barkeri (see paper)
DMDB_EUBBA / Q0QLE1 2,3-dimethylmalate dehydratase small subunit; EC 4.2.1.85 from Eubacterium barkeri (Clostridium barkeri) (see 2 papers)
    36% identity, 73% coverage of query (60.5 bits)

Build an alignment

Build an alignment for H281DRAFT_02540 and 18 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory