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Searching for up to 100 curated homologs for H281DRAFT_02718 FitnessBrowser__Burk376:H281DRAFT_02718 (466 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

tynA / D7F5L6 tyramine oxidase subunit A (EC 1.4.3.4) from Pseudomonas putida (see paper)
    42% identity, 92% coverage of query (308 bits)

Q51890 L-amino-acid oxidase (EC 1.4.3.2) from Proteus mirabilis (see paper)
aad / AAA86752.1 amino acid deaminase from Proteus mirabilis (see paper)
    30% identity, 90% coverage of query (212 bits)

5fjmA / A0A158RFS7 Structure of l-amino acid deaminase from proteus myxofaciens (see paper)
    30% identity, 90% coverage of query (195 bits)

5fjnA Structure of l-amino acid deaminase from proteus myxofaciens in complex with anthranilate
    30% identity, 90% coverage of query (195 bits)

Build an alignment

Build an alignment for H281DRAFT_02718 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q9LCB2 L-amino-acid oxidase (EC 1.4.3.2) from Proteus vulgaris (see paper)
    29% identity, 90% coverage of query (186 bits)

5hxwA / Q9LCB2 L-amino acid deaminase from proteus vulgaris (see paper)
    29% identity, 90% coverage of query (186 bits)

B2ZHY0 L-amino-acid oxidase (EC 1.4.3.2) from Proteus mirabilis (see paper)
    29% identity, 90% coverage of query (177 bits)

5i39A / Q9LCB2 High resolution structure of l-amino acid deaminase from proteus vulgaris with the deletion of the specific insertion sequence (see paper)
    28% identity, 90% coverage of query (159 bits)

Q76M73 proline dehydrogenase (EC 1.5.5.2) from Thermococcus profundus (see 2 papers)
    25% identity, 86% coverage of query (113 bits)

Q5JFG2 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    25% identity, 86% coverage of query (111 bits)

lhpB / Q9I477 D-hydroxyproline dehydrogenase β subunit from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    28% identity, 91% coverage of query (101 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    24% identity, 86% coverage of query (99.0 bits)

SOX_HUMAN / Q9P0Z9 Peroxisomal sarcosine oxidase; PSO; L-pipecolate oxidase; L-pipecolic acid oxidase; EC 1.5.3.1; EC 1.5.3.7 from Homo sapiens (Human) (see paper)
Q9P0Z9 L-pipecolate oxidase (EC 1.5.3.7) from Homo sapiens (see paper)
    25% identity, 89% coverage of query (98.6 bits)

Q9DBT9 dimethylglycine dehydrogenase (EC 1.5.8.4) from Mus musculus (see paper)
    24% identity, 88% coverage of query (93.2 bits)

PIPOX / Q8N6Z6 L-pipecolate oxidase (EC 1.5.3.7) from Homo sapiens (see 2 papers)
    25% identity, 89% coverage of query (92.8 bits)

Q5RKL4 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see paper)
    25% identity, 88% coverage of query (91.7 bits)

Dmgdh / Q63342 dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) from Rattus norvegicus (see 9 papers)
M2GD_RAT / Q63342 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Rattus norvegicus (Rat) (see 3 papers)
Q63342 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see 3 papers)
    25% identity, 88% coverage of query (89.7 bits)

4pabB / Q63342 Crystal structure of the precursor form of rat dmgdh complexed with tetrahydrofolate (see paper)
    25% identity, 88% coverage of query (89.7 bits)

SARDH / Q9UL12 sarcosine dehydrogenase (EC 1.5.8.3) from Homo sapiens (see 5 papers)
SARDH_HUMAN / Q9UL12 Sarcosine dehydrogenase, mitochondrial; SarDH; BPR-2; EC 1.5.8.3 from Homo sapiens (Human) (see 2 papers)
    24% identity, 90% coverage of query (89.0 bits)

mabO / Q8GAI3 4-methylaminobutyrate oxidase (demethylating) (EC 1.5.3.19) from Paenarthrobacter nicotinovorans (see 2 papers)
MABO1_PAENI / Q8GAI3 4-methylaminobutanoate oxidase (formaldehyde-forming); MABO; Demethylating gamma-N-methylaminobutyrate oxidase; Gamma-N-methylaminobutyrate oxidase 1; EC 1.5.3.19 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
    25% identity, 91% coverage of query (88.6 bits)

DMGDH / Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 6 papers)
M2GD_HUMAN / Q9UI17 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Homo sapiens (Human) (see 2 papers)
Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 2 papers)
    23% identity, 88% coverage of query (85.9 bits)

SarDH / Q64380 sarcosine dehydrogenase (EC 1.5.8.3) from Rattus norvegicus (see 10 papers)
SARDH_RAT / Q64380 Sarcosine dehydrogenase, mitochondrial; SarDH; EC 1.5.8.3 from Rattus norvegicus (Rat) (see 2 papers)
    25% identity, 90% coverage of query (83.6 bits)

GLYOX_PSEPK / Q88Q83 Glycine oxidase; GO; EC 1.4.3.19 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88Q83 glycine oxidase (EC 1.4.3.19) from Pseudomonas putida (see paper)
    25% identity, 86% coverage of query (71.2 bits)

nmpC / A0A222FYP8 4-methylaminobutanoate oxidase (EC 1.5.3.21) from Alicycliphilus sp. (see paper)
    23% identity, 82% coverage of query (64.7 bits)

7exsA / B9L163 Thermomicrobium roseum sarcosine oxidase mutant - s320r (see paper)
    27% identity, 89% coverage of query (61.6 bits)

dada* / AAB39269.1 dada* from Pseudomonas aeruginosa (see 2 papers)
    25% identity, 85% coverage of query (61.2 bits)

Q6ITC6 sarcosine oxidase (EC 1.5.3.1) from Bacillus sp. (in: Bacteria) (see 2 papers)
    21% identity, 89% coverage of query (60.5 bits)

AZOBR_RS08020 D-alanine dehydrogenase (EC 1.4.99.-) from Azospirillum brasilense Sp245
    23% identity, 88% coverage of query (60.1 bits)

ooxB / Q59159 octopine oxidase subunit B from Agrobacterium tumefaciens (strain Ach5) (see paper)
    23% identity, 81% coverage of query (57.8 bits)

Q1XEP4 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus versutus (see paper)
    24% identity, 86% coverage of query (54.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory