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Searching for up to 100 curated homologs for H281DRAFT_02853 FitnessBrowser__Burk376:H281DRAFT_02853 (564 a.a.)

Found high-coverage hits (≥70%) to 52 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q63MI6 alpha,alpha-trehalase (EC 3.2.1.28) from Burkholderia pseudomallei (see paper)
    78% identity, 88% coverage of query (802 bits)

Q3BXX2 alpha,alpha-trehalase (EC 3.2.1.28) from Xanthomonas campestris (see paper)
    57% identity, 88% coverage of query (563 bits)

2jjbA Family 37 trehalase from escherichia coli in complex with casuarine-6- o-alpha-glucopyranose
    55% identity, 88% coverage of query (550 bits)

Tre / b1197 periplasmic trehalase (EC 3.2.1.28) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
treA / P13482 periplasmic trehalase (EC 3.2.1.28) from Escherichia coli (strain K12) (see 11 papers)
TREA_ECOLI / P13482 Periplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Tre37A; EC 3.2.1.28 from Escherichia coli (strain K12) (see 2 papers)
AAC74281.1 α,α-trehalase (periplasmic) (TreA;OsmA) (Tre37A) (EC 3.2.1.28) (see protein)
    56% identity, 88% coverage of query (548 bits)

AO356_24205 Alpha,alpha-trehalase (EC 3.2.1.28) from Pseudomonas fluorescens FW300-N2C3
    53% identity, 93% coverage of query (548 bits)

2jg0A / P13482 Family 37 trehalase from escherichia coli in complex with 1- thiatrehazolin (see paper)
    56% identity, 88% coverage of query (545 bits)

2jf4A Family 37 trehalase from escherichia coli in complex with validoxylamine
    55% identity, 88% coverage of query (540 bits)

2wynA Structure of family 37 trehalase from escherichia coli in complex with a casuarine-6-o-a-d-glucoside analogue
    55% identity, 88% coverage of query (539 bits)

5z66A Structure of periplasmic trehalase from diamondback moth gut bacteria complexed with validoxylamine (see paper)
    55% identity, 88% coverage of query (538 bits)

TreF / b3519 cytoplasmic trehalase (EC 3.2.1.28) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
treF / P62601 cytoplasmic trehalase (EC 3.2.1.28) from Escherichia coli (strain K12) (see 3 papers)
TREF_ECOLI / P62601 Cytoplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Escherichia coli (strain K12) (see paper)
AAC76544.1 trehalase (TreF;b3519) (EC 3.2.1.28) (see protein)
    51% identity, 88% coverage of query (494 bits)

D4I261 alpha,alpha-trehalase (EC 3.2.1.28) from Erwinia amylovora (see paper)
    49% identity, 88% coverage of query (476 bits)

P32358 alpha,alpha-trehalase (EC 3.2.1.28) from Bombyx mori (see paper)
BAA02909.1 trehalase (Treh1) (EC 3.2.1.28) (see protein)
    34% identity, 91% coverage of query (274 bits)

A0A2S1WCH9 alpha,alpha-trehalase (EC 3.2.1.28) from Holothuria leucospilota (see paper)
    32% identity, 92% coverage of query (252 bits)

TREA_RABIT / P19813 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Oryctolagus cuniculus (Rabbit) (see paper)
AAA63460.1 trehalase (TreH;TreA) (EC 3.2.1.28) (see protein)
    33% identity, 88% coverage of query (251 bits)

A6MIZ4 alpha,alpha-trehalase (EC 3.2.1.28) from Physcomitrium patens (see paper)
    34% identity, 76% coverage of query (248 bits)

Q9GYK9 alpha,alpha-trehalase (EC 3.2.1.28) from Caenorhabditis elegans (see paper)
    31% identity, 89% coverage of query (246 bits)

Q9JLT2 alpha,alpha-trehalase (EC 3.2.1.28) from Mus musculus (see 2 papers)
AAF61430.1 trehalase (EC 3.2.1.28) (see protein)
    33% identity, 88% coverage of query (244 bits)

Q9XEY7 alpha,alpha-trehalase (EC 3.2.1.28) from Glycine max (see paper)
AAD22970.1 trehalase 1 (Tre1) (EC 3.2.1.28) (see protein)
    34% identity, 77% coverage of query (242 bits)

ABO20846.1 trehalase 1 (Treh-1) (EC 3.2.1.28) (see protein)
    32% identity, 88% coverage of query (241 bits)

D2KHJ0 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera litura (see paper)
    31% identity, 87% coverage of query (241 bits)

Q9W2M2 alpha,alpha-trehalase (EC 3.2.1.28) from Drosophila melanogaster (see paper)
    32% identity, 86% coverage of query (239 bits)

Q9W2M2 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Drosophila melanogaster (Fruit fly)
    32% identity, 86% coverage of query (239 bits)

AGO32658.1 trehalase (Tre1;TmTre1) (soluble; midgut) (EC 3.2.1.28) (see protein)
    31% identity, 91% coverage of query (238 bits)

Q3MV18 alpha,alpha-trehalase (EC 3.2.1.28) from Bombyx mori (see paper)
BAE45249.1 trehalase 2 (Treh2;Treh-2) (EC 3.2.1.28) (see protein)
    33% identity, 88% coverage of query (236 bits)

LOC410795 / A8J4S9 trehalase (bound form) (EC 3.2.1.28) from Apis mellifera (see 3 papers)
TREA_APIME / A8J4S9 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Apis mellifera (Honeybee) (see 2 papers)
A8J4S9 alpha,alpha-trehalase (EC 3.2.1.28) from Apis mellifera (see 2 papers)
BAF81545.1 α,α-trehalase (EC 3.2.1.28) (see protein)
BAF81545.1 trehalase from Apis mellifera (see paper)
    33% identity, 93% coverage of query (236 bits)

D2KWM9 alpha,alpha-trehalase (EC 3.2.1.28) from Nicotiana tabacum (see paper)
    32% identity, 90% coverage of query (235 bits)

TREA_HUMAN / O43280 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Homo sapiens (Human) (see 3 papers)
O43280 alpha,alpha-trehalase (EC 3.2.1.28) from Homo sapiens (see paper)
    32% identity, 88% coverage of query (233 bits)

A0A0F6PAZ3 alpha,alpha-trehalase (EC 3.2.1.28) from Helicoverpa armigera (see paper)
    32% identity, 92% coverage of query (231 bits)

B0M0J3 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera exigua (see paper)
ABY86218.1 trehalase-1 (Tre-1;SeTre-1) (EC 3.2.1.28) (see protein)
    32% identity, 87% coverage of query (230 bits)

A0A0F6PB63 alpha,alpha-trehalase (EC 3.2.1.28) from Helicoverpa armigera (see paper)
    30% identity, 86% coverage of query (229 bits)

Q0ZIF5 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera frugiperda (see 2 papers)
ABE27189.1 trehalase (SfTre1) (soluble; midgut) (EC 3.2.1.28) (see protein)
    30% identity, 87% coverage of query (228 bits)

BAA24381.1 trehalase (TreA;TreH) (EC 3.2.1.28) (see protein)
    32% identity, 88% coverage of query (228 bits)

A7XZC0 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera exigua (see paper)
ABU95354.1 trehalase 2 (Tre-2;Treh-2;SeTre-2) (EC 3.2.1.28) (see protein)
    32% identity, 88% coverage of query (226 bits)

J7EJ73 alpha,alpha-trehalase (EC 3.2.1.28) from Chironomus riparius (see paper)
ADT91708.1 trehalase (Tre-1) (EC 3.2.1.28) (see protein)
    34% identity, 88% coverage of query (226 bits)

AGL34007.2 membrane-bound trehalase (ALTre-2) (EC 3.2.1.28) (see protein)
    33% identity, 91% coverage of query (224 bits)

Build an alignment

Build an alignment for H281DRAFT_02853 and 35 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

P32359 alpha,alpha-trehalase (EC 3.2.1.28) from Tenebrio molitor (see paper)
BAA01951.1 trehalase (EC 3.2.1.28) (see protein)
    29% identity, 90% coverage of query (222 bits)

C0LZJ7 alpha,alpha-trehalase (EC 3.2.1.28) from Nilaparvata lugens (see paper)
    33% identity, 88% coverage of query (219 bits)

AGK89798.1 soluble trehalase (ALTre-1) (EC 3.2.1.28) (see protein)
    34% identity, 88% coverage of query (219 bits)

B5ATV4 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera frugiperda (see 2 papers)
ACF94698.1 trehalase (SfTre2) (EC 3.2.1.28) (see protein)
    32% identity, 88% coverage of query (217 bits)

D2KHI9 alpha,alpha-trehalase (EC 3.2.1.28) from Spodoptera litura (see paper)
    32% identity, 88% coverage of query (216 bits)

C0LZJ6 alpha,alpha-trehalase (EC 3.2.1.28) from Nilaparvata lugens (see paper)
ACN85420.1 trehalase (Tre-1) (soluble) (EC 3.2.1.28) (see protein)
    32% identity, 86% coverage of query (214 bits)

TRE1_ARATH / Q9SU50 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Trehalase 1; AtTRE1; EC 3.2.1.28 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9SU50 alpha,alpha-trehalase (EC 3.2.1.28) from Arabidopsis thaliana (see paper)
CAB51647.1 trehalase (AtTre1;At4g24040/T19F6.30) (plasma membrane-bound) (EC 3.2.1.28) (see protein)
    31% identity, 79% coverage of query (208 bits)

7eawA / Q9SU50 Trehalase of arabidopsis thaliana acid mutant -d380a trehalose complex
    30% identity, 84% coverage of query (206 bits)

B0CV22 alpha,alpha-trehalase (EC 3.2.1.28) from Laccaria bicolor (see paper)
    31% identity, 85% coverage of query (203 bits)

B6ZIV1 alpha,alpha-trehalase (EC 3.2.1.28) from Nostoc punctiforme (see paper)
BAG85338.1 trehalase (TreH) (EC 3.2.1.28) (see protein)
treH / BAG85338.1 trehalase from Nostoc punctiforme (see paper)
    33% identity, 71% coverage of query (199 bits)

treH / BAG70920.1 trehalase, partial from Nostoc punctiforme (see paper)
    33% identity, 71% coverage of query (198 bits)

P52494 alpha,alpha-trehalase (EC 3.2.1.28) from Candida albicans (see paper)
CAA64476.1 neutral trehalase (Ntc1;CaNTC1) (EC 3.2.1.28) (see protein)
    29% identity, 73% coverage of query (146 bits)

NTH1 neutral trehalase from Candida albicans (see 2 papers)
    29% identity, 73% coverage of query (145 bits)

TREA_BEAB2 / J5K1E2 Cytosolic neutral trehalase; Alpha,alpha-trehalase; Alpha-trehalose glucohydrolase; EC 3.2.1.28 from Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae) (see paper)
A1YQE2 alpha,alpha-trehalase (EC 3.2.1.28) from Beauveria bassiana (see paper)
ABM16911.1 neutral trehalase (Nth1;BbNTH1) (EC 3.2.1.28) (see protein)
    28% identity, 74% coverage of query (145 bits)

TREB_PYRO7 / O42622 Cytosolic neutral trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae) (see paper)
AAN46743.1 neutral trehalase (NTH1) (EC 3.2.1.28) (see protein)
EAA53721.1 neutral trehalase (NTH1;MG09471.4) (EC 3.2.1.28) (see protein)
PTH9 neutral trehalase from Magnaporthe grisea 70-15 (see paper)
    27% identity, 71% coverage of query (140 bits)

AAB88889.1 trehalase (EC 3.2.1.28) (see protein)
    27% identity, 71% coverage of query (140 bits)

CAK43979.1 trehalase B (TreB;An01g09290) (EC 3.2.1.28) (see protein)
    28% identity, 74% coverage of query (135 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory