Searching for up to 100 curated homologs for H281DRAFT_03194 FitnessBrowser__Burk376:H281DRAFT_03194 (386 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

METN_BACSU / O32169 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32169 MetN (C) (aka YusC), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
    47% identity, 81% coverage of query (286 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    44% identity, 92% coverage of query (278 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    44% identity, 92% coverage of query (277 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    44% identity, 92% coverage of query (277 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    44% identity, 92% coverage of query (277 bits)

TC 3.A.1.24.4 / Q8NSN2 Methionine import ATP-binding protein metN, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum (see paper)
    46% identity, 83% coverage of query (274 bits)

TC 3.A.1.24.5 / Q9HT70 Methionine import ATP-binding protein MetN 2, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    49% identity, 83% coverage of query (266 bits)

TC 3.A.1.24.3 / Q8K8K8 AtmD (MetN), component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
    40% identity, 83% coverage of query (241 bits)

6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
    32% identity, 72% coverage of query (102 bits)

3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    32% identity, 72% coverage of query (102 bits)

3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
    32% identity, 72% coverage of query (102 bits)

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Build an alignment for H281DRAFT_03194 and 11 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ABC2_SCHPO / Q10185 ATP-binding cassette transporter abc2; ABC transporter abc2; ATP-energized glutathione S-conjugate pump abc2; Glutathione S-conjugate-transporting ATPase abc2; EC 7.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
TC 3.A.1.208.16 / Q10185 The vacuolar Abc2p (SPAC3F10.11c) transporter for xenobiotics, glutathione S-conjugates and monochlorobimane from Schizosaccharomyces pombe (Fission yeast) (see 3 papers)
abc2 / RF|NP_593943.2 ATP-binding cassette transporter abc2 from Schizosaccharomyces pombe (see 3 papers)
    24% identity, 81% coverage of query (63.9 bits)

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