Searching for up to 100 curated homologs for H281DRAFT_03220 FitnessBrowser__Burk376:H281DRAFT_03220 (310 a.a.)
Found high-coverage hits (≥70%) to 60 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BPHYT_RS22715 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Burkholderia phytofirmans PsJN
94% identity, 99% coverage of query (575 bits)
HSERO_RS06870 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Herbaspirillum seropedicae SmR1
79% identity, 96% coverage of query (465 bits)
Ac3H11_603 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Acidovorax sp. GW101-3H11
73% identity, 94% coverage of query (438 bits)
KDADA_AZOBR / Q1JUQ0 L-2-keto-3-deoxyarabonate dehydratase; L-KDA dehydratase; 2-dehydro-3-deoxy-L-arabinonate dehydratase; L-2-keto-3-deoxyarabinonate dehydratase; EC 4.2.1.43 from Azospirillum brasilense (see 2 papers)
Q1JUQ0 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) from Azospirillum brasilense (see 2 papers)
72% identity, 97% coverage of query (421 bits)
Build an alignment for H281DRAFT_03220 and 4 homologs with ≥ 30% identity
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Q7D313 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
29% identity, 91% coverage of query (96.7 bits)
3na8A / Q9I6R5 Crystal structure of a putative dihydrodipicolinate synthetase from pseudomonas aeruginosa
29% identity, 90% coverage of query (95.5 bits)
3nevA / P75682 Crystal structure of yage, a prophage protein from e. Coli k12 in complex with kdgal (see paper)
28% identity, 78% coverage of query (93.6 bits)
YagE / b0268 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yagE / P75682 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli (strain K12) (see 8 papers)
YAGE_ECOLI / P75682 Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE; KDG aldolase YagE; Putative 2-dehydro-3-deoxy-D-pentonate aldolase YagE; EC 4.1.2.51; EC 4.1.2.28 from Escherichia coli (strain K12) (see 4 papers)
P75682 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) from Escherichia coli (see paper)
28% identity, 78% coverage of query (93.6 bits)
4ptnA Crystal structure of yage, a kdg aldolase protein in complex with magnesium cation coordinated l-glyceraldehyde
28% identity, 78% coverage of query (93.6 bits)
4onvA Crystal structure of yage, a kdg aldolase protein in complex with 2- keto-3-deoxy gluconate
28% identity, 78% coverage of query (93.6 bits)
4oe7D Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
28% identity, 78% coverage of query (93.6 bits)
4oe7B Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
28% identity, 78% coverage of query (93.6 bits)
4oe7A Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
28% identity, 78% coverage of query (93.6 bits)
dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
24% identity, 75% coverage of query (87.8 bits)
dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
24% identity, 92% coverage of query (85.9 bits)
O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus (see paper)
25% identity, 71% coverage of query (80.1 bits)
1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
25% identity, 94% coverage of query (79.0 bits)
DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
25% identity, 94% coverage of query (79.0 bits)
DAPA_MYCTU / P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
26% identity, 82% coverage of query (76.6 bits)
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
26% identity, 82% coverage of query (76.6 bits)
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis
26% identity, 82% coverage of query (76.6 bits)
5j5dA / P9WP25 Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
26% identity, 82% coverage of query (76.3 bits)
DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
24% identity, 78% coverage of query (74.3 bits)
dapA2 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis (see paper)
24% identity, 74% coverage of query (73.9 bits)
YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
23% identity, 84% coverage of query (73.2 bits)
4i7wA / F0L8Z6 Agrobacterium tumefaciens dhdps with lysine and pyruvate
27% identity, 92% coverage of query (70.1 bits)
DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see 2 papers)
27% identity, 92% coverage of query (67.8 bits)
Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
25% identity, 75% coverage of query (66.6 bits)
3qfeA Crystal structures of a putative dihydrodipicolinate synthase family protein from coccidioides immitis
26% identity, 74% coverage of query (66.2 bits)
dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
24% identity, 88% coverage of query (65.9 bits)
dapA / CAA92211.1 dihydrodipicolinate synthase from Prochlorococcus marinus (see paper)
28% identity, 76% coverage of query (64.7 bits)
DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti (see 2 papers)
25% identity, 90% coverage of query (63.2 bits)
4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
24% identity, 90% coverage of query (62.8 bits)
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
24% identity, 90% coverage of query (62.8 bits)
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
24% identity, 90% coverage of query (62.8 bits)
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
24% identity, 90% coverage of query (62.8 bits)
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
24% identity, 90% coverage of query (62.8 bits)
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
24% identity, 90% coverage of query (62.8 bits)
5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
22% identity, 88% coverage of query (61.6 bits)
DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
22% identity, 88% coverage of query (61.2 bits)
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
22% identity, 88% coverage of query (61.2 bits)
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
21% identity, 88% coverage of query (60.5 bits)
C8P490 N-acetylneuraminate lyase (EC 4.1.3.3) from Limosilactobacillus antri (see paper)
23% identity, 91% coverage of query (58.2 bits)
dapA / P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum (see paper)
dapA / CAA79714.1 dihydrodipicolinate synthase from Corynebacterium glutamicum (see paper)
23% identity, 91% coverage of query (57.4 bits)
8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
23% identity, 94% coverage of query (54.7 bits)
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
22% identity, 91% coverage of query (54.3 bits)
nanA sialic acid lyase from Clostridium perfringens (see paper)
23% identity, 93% coverage of query (53.5 bits)
2wpbA / P0A6L4 Crystal structure of the e192n mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2r,3r)-2,3,4- trihydroxy-n,n-dipropylbutanamide in space group p21 crystal form i (see paper)
23% identity, 88% coverage of query (53.5 bits)
nanA / Q9S4K9 N-acetylneuraminate lyase (EC 4.1.3.3) from Clostridium perfringens (strain 13 / Type A) (see 6 papers)
nanA / GB|CAA73375.1 N-acetylneuraminate lyase; EC 4.1.3.3 from Clostridium perfringens (see 4 papers)
23% identity, 93% coverage of query (53.5 bits)
Q9S4K9 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Clostridium perfringens (strain 13 / Type A)
23% identity, 93% coverage of query (53.5 bits)
Q7D3Z9 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
23% identity, 73% coverage of query (52.8 bits)
NANA_LACPL / P59407 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
23% identity, 87% coverage of query (52.8 bits)
Npl / b3225 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 21 papers)
nanA / P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (strain K12) (see 30 papers)
NANA_ECOLI / P0A6L4 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Escherichia coli (strain K12) (see 4 papers)
P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (see 4 papers)
nanA N-acetylneuraminate lyase; EC 4.1.3.3 from Escherichia coli K12 (see 6 papers)
23% identity, 88% coverage of query (52.8 bits)
4bwlC Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
23% identity, 88% coverage of query (52.8 bits)
4bwlA Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
23% identity, 88% coverage of query (52.8 bits)
3lbcD D-sialic acid aldolase complexed with l-arabinose
23% identity, 88% coverage of query (52.8 bits)
1fdzA N-acetylneuraminate lyase in complex with pyruvate via borohydride reduction
23% identity, 88% coverage of query (50.4 bits)
1fdyA N-acetylneuraminate lyase in complex with hydroxypyruvate
23% identity, 88% coverage of query (50.4 bits)
kdgD / Q6FFQ1 5-dehydro-4-deoxyglucarate dehydratase subunit (EC 4.2.1.41) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KDGD_ACIAD / Q6FFQ1 Probable 5-dehydro-4-deoxyglucarate dehydratase; 5-keto-4-deoxy-glucarate dehydratase; KDGDH; EC 4.2.1.41 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ1 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Acinetobacter baylyi (see 2 papers)
21% identity, 94% coverage of query (50.1 bits)
4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
22% identity, 85% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory