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Searching for up to 100 curated homologs for H281DRAFT_03278 FitnessBrowser__Burk376:H281DRAFT_03278 (402 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ADHB_BACSU / O06012 Uncharacterized zinc-type alcohol dehydrogenase-like protein AdhB; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
    38% identity, 100% coverage of query (268 bits)

YbdR / b0608 putative Zn2+-dependent alcohol dehydrogenase YbdR from Escherichia coli K-12 substr. MG1655 (see paper)
    37% identity, 100% coverage of query (247 bits)

YHG1_SCHPO / Q9P6I8 Zinc-type alcohol dehydrogenase-like protein C1198.01; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    34% identity, 99% coverage of query (222 bits)

adh2 / Q768S7 NAD+-dependent secondary alcohol dehydrogenase II monomer from Gordonia sp. (strain TY-5) (see paper)
    36% identity, 97% coverage of query (206 bits)

B2ZRE3 alcohol dehydrogenase (EC 1.1.1.1) from Thermus sp. (see paper)
    32% identity, 98% coverage of query (197 bits)

4cpdA / B2ZRE3 Alcohol dehydrogenase tadh from thermus sp. Atn1
    32% identity, 98% coverage of query (197 bits)

D4GP73 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloferax volcanii (see paper)
    33% identity, 100% coverage of query (182 bits)

ADH_CUPNH / Q0KDL6 Alcohol dehydrogenase; EC 1.1.1.1; EC 1.1.1.4; EC 1.2.1.3 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 2 papers)
    32% identity, 100% coverage of query (181 bits)

Q9HMB6 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Halobacterium sp. (see paper)
    32% identity, 99% coverage of query (173 bits)

Q5V676 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloarcula marismortui (see paper)
    33% identity, 100% coverage of query (170 bits)

YYCR_BACSU / Q45604 Uncharacterized zinc-type alcohol dehydrogenase-like protein YycR; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
    32% identity, 95% coverage of query (157 bits)

A0A6F8QRG1 formaldehyde dismutase (EC 1.2.98.1) from Methylobacterium sp. FD1 (see paper)
    31% identity, 98% coverage of query (156 bits)

Build an alignment

Build an alignment for H281DRAFT_03278 and 12 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q5M4K4 alcohol dehydrogenase (EC 1.1.1.1) from Streptococcus thermophilus (see paper)
    27% identity, 98% coverage of query (142 bits)

M5AJW4 coniferyl-alcohol dehydrogenase (EC 1.1.1.194); aryl-alcohol dehydrogenase (EC 1.1.1.90) from Streptomyces sp. (see 2 papers)
    30% identity, 93% coverage of query (118 bits)

A0A3S7PMB5 D-xylulose reductase (EC 1.1.1.9) from Pichia kudriavzevii (see paper)
    25% identity, 96% coverage of query (111 bits)

FADH_AMYME / P80094 S-(hydroxymethyl)mycothiol dehydrogenase; NAD/mycothiol-dependent formaldehyde dehydrogenase; MD-FALDH; EC 1.1.1.306 from Amycolatopsis methanolica (see paper)
CH_016274 NAD/mycothiol-dependent formaldehyde dehydrogenase; EC 1.2.1.66 from Amycolatopsis methanolica (see 3 papers)
    29% identity, 94% coverage of query (110 bits)

mscR / O53533 mycothiol-dependent formaldehyde dehydrogenase subunit (EC 1.1.1.306) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 5 papers)
    31% identity, 92% coverage of query (109 bits)

ladA / A2QAC0 L-arabinitol 4-dehydrogenase (EC 1.1.1.9; EC 1.1.1.12) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 2 papers)
LAD_ASPNC / A2QAC0 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 3 papers)
A2QAC0 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Aspergillus niger (see 2 papers)
    26% identity, 96% coverage of query (100 bits)

3m6iA / Q7SI09 L-arabinitol 4-dehydrogenase (see paper)
    26% identity, 97% coverage of query (99.0 bits)

LAD_NEUCR / Q7SI09 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 2 papers)
Q7SI09 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Neurospora crassa (see paper)
    26% identity, 97% coverage of query (99.0 bits)

LAD_PENRW / B6HI95 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) (see paper)
B6HI95 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Penicillium chrysogenum (see paper)
    24% identity, 93% coverage of query (88.6 bits)

2eihA / Q5SL27 Crystal structure of NAD-dependent alcohol dehydrogenase
    25% identity, 97% coverage of query (85.5 bits)

5k1sA / Q1D4I2 Crystal structure of aibc (see paper)
    30% identity, 71% coverage of query (85.5 bits)

lad1 / Q96V44 D-galactitol dehydrogenase (EC 1.1.1.12) from Hypocrea jecorina (see paper)
LAD_HYPJE / Q96V44 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Hypocrea jecorina (Trichoderma reesei) (see 4 papers)
Q96V44 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Trichoderma reesei (see 5 papers)
    25% identity, 94% coverage of query (84.7 bits)

6ie0B / O34788 X-ray crystal structure of 2r,3r-butanediol dehydrogenase from bacillus subtilis
    23% identity, 100% coverage of query (71.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory