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Searching for up to 100 curated homologs for H281DRAFT_03380 FitnessBrowser__Burk376:H281DRAFT_03380 (515 a.a.)

Found high-coverage hits (≥70%) to 51 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

HSERO_RS05250 ABC transporter for L-fucose, ATPase component from Herbaspirillum seropedicae SmR1
    56% identity, 96% coverage of query (530 bits)

Q6VMN4 ABC-type D-xylose transporter (EC 7.5.2.10) from Thermoanaerobacter ethanolicus (see paper)
    49% identity, 95% coverage of query (479 bits)

AO353_21385 m-Inositol ABC transporter, ATPase component (itaA) from Pseudomonas fluorescens FW300-N2E3
    48% identity, 96% coverage of query (455 bits)

RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
    47% identity, 95% coverage of query (455 bits)

TC 3.A.1.2.20 / G4FGN3 Monosaccharide-transporting ATPase, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    47% identity, 96% coverage of query (454 bits)

PS417_11890 Inositol transport system ATP-binding protein from Pseudomonas simiae WCS417
    46% identity, 100% coverage of query (452 bits)

MglA / b2149 D-galactose/methyl-galactoside ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 6 papers)
MglA / P0AAG8 D-galactose/methyl-galactoside ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.2.3 / P0AAG8 Galactose/methyl galactoside import ATP-binding protein MglA aka B2149, component of Galactose/glucose (methyl galactoside) porter from Escherichia coli (see 7 papers)
    45% identity, 95% coverage of query (444 bits)

MGLA_SALTY / P23924 Galactose/methyl galactoside import ATP-binding protein MglA; EC 7.5.2.11 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    44% identity, 96% coverage of query (442 bits)

TC 3.A.1.2.19 / Q9X051 Ribose import ATP-binding protein RbsA 2, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    46% identity, 96% coverage of query (434 bits)

TC 3.A.1.2.13 / A6VKS8 RbsA, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    45% identity, 96% coverage of query (424 bits)

TC 3.A.1.2.26 / A6LW11 Xylose import ATP-binding protein XylG, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
    43% identity, 96% coverage of query (422 bits)

TC 3.A.1.2.5 / O05176 GguA aka ATU2347 aka AGR_C_4264, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium radiobacter (see paper)
    45% identity, 94% coverage of query (421 bits)

HSERO_RS11485 D-ribose ABC transporter, ATPase component RbsA from Herbaspirillum seropedicae SmR1
    47% identity, 95% coverage of query (418 bits)

Q73KK2 ABC-type D-galactose transporter (EC 7.5.2.11) from Treponema denticola (see paper)
    42% identity, 95% coverage of query (414 bits)

TC 3.A.1.2.9 / Q7BSH4 RhaT, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii)
    44% identity, 97% coverage of query (413 bits)

HSERO_RS03640 D-mannose ABC transporter, ATPase component from Herbaspirillum seropedicae SmR1
    44% identity, 95% coverage of query (404 bits)

Pf1N1B4_6034 D-ribose ABC transporter, ATPase component RbsA from Pseudomonas fluorescens FW300-N1B4
    45% identity, 96% coverage of query (402 bits)

BPHYT_RS16930 D-galactose ABC transporter, ATPase component from Burkholderia phytofirmans PsJN
    44% identity, 95% coverage of query (397 bits)

XylG / b3567 xylose ABC transporter ATP binding subunit (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
XylG / P37388 xylose ABC transporter ATP binding subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see 2 papers)
XYLG_ECOLI / P37388 Xylose import ATP-binding protein XylG; EC 7.5.2.10 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.4 / P37388 XylG aka B3567, component of Xylose porter from Escherichia coli (see 4 papers)
xylG / GB|AAC76591.1 D-xylose ABC transporter, ATP-binding protein; EC 3.6.3.17 from Escherichia coli K12 (see 2 papers)
    43% identity, 96% coverage of query (397 bits)

FRUK_BIFLO / Q8G847 Fructose import ATP-binding protein FruK; EC 7.5.2.- from Bifidobacterium longum (strain NCC 2705) (see paper)
    43% identity, 94% coverage of query (395 bits)

AraG / b1900 arabinose ABC transporter ATP binding subunit (EC 7.5.2.13; EC 7.5.2.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
AraG / P0AAF3 arabinose ABC transporter ATP binding subunit (EC 7.5.2.13) from Escherichia coli (strain K12) (see paper)
ARAG_ECOLI / P0AAF3 Arabinose import ATP-binding protein AraG; EC 7.5.2.12 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.2.2 / P0AAF3 Arabinose import ATP-binding protein AraG aka B1900, component of Arabinose porter from Escherichia coli (see 6 papers)
araG / RF|NP_416413.1 L-arabinose ABC transporter, ATP-binding protein AraG; EC 3.6.3.17 from Escherichia coli K12 (see paper)
    43% identity, 95% coverage of query (394 bits)

TC 3.A.1.2.21 / B8H229 Inositol transport ATP-binding protein IatA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    44% identity, 95% coverage of query (391 bits)

PS417_18400 D-ribose ABC transporter, ATPase component RbsA from Pseudomonas simiae WCS417
    44% identity, 96% coverage of query (387 bits)

RR42_RS03360 fructose ABC transporter, ATPase component (FrcA) from Cupriavidus basilensis FW507-4G11
    46% identity, 93% coverage of query (387 bits)

YtfR / b4485 galactofuranose ABC transporter putative ATP binding subunit (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see paper)
ytfR / Q6BEX0 galactofuranose ABC transporter putative ATP binding subunit (EC 7.5.2.9) from Escherichia coli (strain K12) (see paper)
    42% identity, 91% coverage of query (382 bits)

PS417_12065 xylitol ABC transporter, ATPase component from Pseudomonas simiae WCS417
    44% identity, 95% coverage of query (380 bits)

Pf6N2E2_5969 ABC transporter for D-galactose/L-arabinose, ATPase component from Pseudomonas fluorescens FW300-N2E2
    43% identity, 95% coverage of query (377 bits)

Pf1N1B4_410 ABC transporter for D-galactose/L-arabinose, ATPase component from Pseudomonas fluorescens FW300-N1B4
    43% identity, 95% coverage of query (374 bits)

AlsA / b4087 D-allose ABC transporter ATP binding subunit (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
AlsA / P32721 D-allose ABC transporter ATP binding subunit (EC 7.5.2.8) from Escherichia coli (strain K12) (see 2 papers)
ALSA_ECOLI / P32721 D-allose import ATP-binding protein AlsA; EC 7.5.2.8 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.2.6 / P32721 AlsA aka B4087, component of D-allose porter from Escherichia coli (see 5 papers)
alsA / GB|AAC77048.1 D-allose import ATP-binding protein AlsA; EC 3.6.3.17 from Escherichia coli K12 (see 5 papers)
    41% identity, 95% coverage of query (372 bits)

TC 3.A.1.2.22 / Q8G3R0 ATP binding protein of ABC transporter for pentoses, component of ABC sugar transporter that plays a role in the probiotic benefits through acetate production from Bifidobacterium longum (strain NCC 2705)
    40% identity, 94% coverage of query (368 bits)

Shewana3_2074 L-arabinose ABC transporter, ATPase component AraV from Shewanella sp. ANA-3
    39% identity, 91% coverage of query (355 bits)

YphE / b2547 putative ABC transporter ATP-binding protein YphE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    41% identity, 90% coverage of query (350 bits)

TC 3.A.1.2.11 / Q92WK2 EryE aka RB0337, component of The erythritol permease, EryEFG (Geddes et al., 2010) (probably orthologous to 3.A.1.2.16) from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    41% identity, 96% coverage of query (342 bits)

H281DRAFT_01113 deoxynucleoside transporter, ATPase component from Paraburkholderia bryophila 376MFSha3.1
    40% identity, 95% coverage of query (342 bits)

NUPA_LACLM / A2RKA7 Nucleoside import ATP-binding protein NupA; EC 7.6.2.- from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.2.17 / A2RKA7 Purine/cytidine ABC transporter ATP-binding protein, component of General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    38% identity, 95% coverage of query (337 bits)

TC 3.A.1.2.16 / Q1M4Q7 ATP binding component of erythritol ABC transporter, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    38% identity, 98% coverage of query (334 bits)

eryE / Q2YIY4 putative erythritol ABC transporter ATP-binding protein from Brucella abortus (strain 2308) (see 3 papers)
    39% identity, 98% coverage of query (333 bits)

NUPO_BACSU / O05253 Guanosine import ATP-binding protein NupO; EC 7.6.2.- from Bacillus subtilis (strain 168) (see paper)
    38% identity, 94% coverage of query (327 bits)

YdeX / b1513 Autoinducer-2 ABC transporter ATP binding subunit (EC 7.6.2.13) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lsrA / P77257 Autoinducer-2 ABC transporter ATP binding subunit (EC 7.6.2.13) from Escherichia coli (strain K12) (see 2 papers)
LSRA_ECOLI / P77257 Autoinducer 2 import ATP-binding protein LsrA; AI-2 import ATP-binding protein LsrA; EGO10A; EC 7.6.2.13 from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.2.8 / P77257 LsrA(C), component of Autoinducer-2 (AI-2, a furanosyl borate diester: (3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Taga et al., 2001, 2003) from Escherichia coli (see 5 papers)
lsrA / RF|NP_416030.1 autoinducer 2 ABC transporter, ATP-binding protein LsrA from Escherichia coli (see 2 papers)
    39% identity, 96% coverage of query (308 bits)

TC 3.A.1.2.12 / Q8DU37 RnsB, component of The (deoxy)ribonucleoside permease; probably takes up all deoxy- and ribonucleosides (cytidine, uridine, adenosine and toxic analogues, fluorocytidine and fluorouridine tested), but not ribose or nucleobases from Streptococcus mutans (see paper)
    35% identity, 94% coverage of query (303 bits)

LSRA_SALTY / Q8ZKQ4 Autoinducer 2 import ATP-binding protein LsrA; AI-2 import ATP-binding protein LsrA; EC 7.6.2.13 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    36% identity, 96% coverage of query (288 bits)

TC 3.A.1.2.10 / O83341 Ribose/galactose ABC transporter, ATP-binding protein aka RbsA-2, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see paper)
    37% identity, 95% coverage of query (284 bits)

TSGDD_HALVD / D4GPW3 Glucose import ATP-binding protein TsgD13; EC 7.5.2.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    36% identity, 93% coverage of query (284 bits)

BPHYT_RS34245 ABC transporter for L-rhamnose/L-fucose/xylitol, ATPase component from Burkholderia phytofirmans PsJN
    34% identity, 90% coverage of query (266 bits)

Build an alignment

Build an alignment for H281DRAFT_03380 and 44 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

1yqtA Rnase-l inhibitor
    23% identity, 86% coverage of query (68.2 bits)

5yv5A Crystal structure of the complex of archaeal ribosomal stalk protein ap1 and archaeal ribosome recycling factor aabce1.
    22% identity, 86% coverage of query (67.8 bits)

ETTA_ECOL6 / A0A0H2VFI8 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    23% identity, 79% coverage of query (64.7 bits)

YjjK / b4391 energy-dependent translational throttle protein EttA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ETTA_ECOLI / P0A9W3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli (strain K12) (see 2 papers)
CH_004211 ABC transporter, ATP-binding protein YjiK from Escherichia coli K12 (see paper)
    23% identity, 79% coverage of query (64.7 bits)

3j5sD / P0A9W3 Etta binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics (see paper)
    23% identity, 79% coverage of query (64.7 bits)

3ozxA Crystal structure of abce1 of sulfolubus solfataricus (-fes domain)
    22% identity, 86% coverage of query (61.6 bits)

5ll6h Structure of the 40s abce1 post-splitting complex in ribosome recycling and translation initiation
    22% identity, 80% coverage of query (58.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory