Searching for up to 100 curated homologs for H281DRAFT_03420 FitnessBrowser__Burk376:H281DRAFT_03420 (341 a.a.)
Found high-coverage hits (≥70%) to 23 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
proH / Q9AQI1 subunit of 4-oxalomesaconate hydratase (EC 4.2.1.83) from Pseudomonas straminea (see 3 papers)
proH / BAB21455.1 4-Oxalomesaconate hydratase from Pseudomonas straminea (see 2 papers)
82% identity, 100% coverage of query (611 bits)
pmdE / Q93PS9 4-carboxy-2-hydroxymuconate hydratase (EC 4.2.1.83) from Comamonas testosteroni (see paper)
Q93PS9 4-oxalomesaconate hydratase (EC 4.2.1.83) from Comamonas testosteroni (see paper)
82% identity, 100% coverage of query (609 bits)
2gwgA / Q6N0R4 Crystal structure of 4-oxalomesaconate hydratase, ligj, from rhodopseudomonas palustris, northeast structural genomics target rpr66.
77% identity, 100% coverage of query (553 bits)
LIGJ_SPHSK / G2IQQ5 2-keto-4-carboxy-3-hexenedioate hydratase; KCH hydratase; EC 4.2.1.- from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see 3 papers)
ligJ / BAA97116.1 4-oxalomesaconate hydratase from Sphingomonas paucimobilis (see 3 papers)
ligJ / BAB88741.1 4-oxalomesaconate hydratase from Sphingomonas paucimobilis (see 5 papers)
63% identity, 100% coverage of query (458 bits)
6dxsA / G2IQQ5 Crystal structure of the ligj hydratase e284q mutant substrate complex with (3z)-2-keto-4-carboxy-3-hexenedioate (see paper)
63% identity, 100% coverage of query (457 bits)
6dxqA Crystal structure of the ligj hydratase product complex with 4- carboxy-4-hydroxy-2-oxoadipate
63% identity, 99% coverage of query (456 bits)
ligY / Q9Z9I9 OH-DDVA meta-cleavage compound hydrolase from Sphingomonas paucimobilis (see paper)
33% identity, 96% coverage of query (180 bits)
6e6iA Crystal structure of 4-methyl hopda bound to ligy from sphingobium sp. Strain syk-6
33% identity, 96% coverage of query (180 bits)
5vn5C / G2IN02 Crystal structure of ligy from sphingobium sp. Strain syk-6 (see paper)
33% identity, 96% coverage of query (179 bits)
Build an alignment for H281DRAFT_03420 and 9 homologs with ≥ 30% identity
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nbaD / A4IT47 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) from Geobacillus thermodenitrificans (strain NG80-2) (see paper)
24% identity, 83% coverage of query (67.4 bits)
4qrnA / Q2GA79 High-resolution crystal structure of 5-carboxyvanillate decarboxylase (target efi-505250) from novosphingobium aromaticivorans dsm 12444 complexed with manganese and 4-hydroxy-3-methoxy-5-nitrobenzoic acid
22% identity, 73% coverage of query (65.1 bits)
4infA Crystal structure of amidohydrolase saro_0799 (target efi-505250) from novosphingobium aromaticivorans dsm 12444 with bound calcium
22% identity, 73% coverage of query (65.1 bits)
ACMSD_RAT / Q8R5M5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Rattus norvegicus (Rat) (see 2 papers)
Q8R5M5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Rattus norvegicus (see 3 papers)
23% identity, 83% coverage of query (56.2 bits)
ACMSD_MOUSE / Q8R519 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Mus musculus (Mouse) (see paper)
Q8R519 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Mus musculus (see paper)
23% identity, 83% coverage of query (55.1 bits)
7pwyA Structure of human dimeric acmsd in complex with the inhibitor tes- 1025
22% identity, 80% coverage of query (53.1 bits)
4ofcA / Q8TDX5 2.0 angstroms x-ray crystal structure of human 2-amino-3- carboxymuconate-6-semialdehye decarboxylase (see paper)
22% identity, 80% coverage of query (52.8 bits)
7pwyC / Q8TDX5 Structure of human dimeric acmsd in complex with the inhibitor tes- 1025 (see paper)
21% identity, 80% coverage of query (52.8 bits)
ACMSD / Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 2 papers)
ACMSD_HUMAN / Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Homo sapiens (Human) (see 2 papers)
Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 5 papers)
22% identity, 80% coverage of query (52.8 bits)
4ih3A 2.5 angstroms x-ray crystal structure of of human 2-amino-3- carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid
22% identity, 80% coverage of query (52.8 bits)
2wm1A The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
22% identity, 80% coverage of query (52.8 bits)
ligW2 / Q84IP8 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 2 papers)
20% identity, 82% coverage of query (52.4 bits)
4qroA / Q12BV1 Crystal structure of dihydroxybenzoic acid decarbboxylase bpro_2061 (target efi-500288) from polaromonas sp. Js666 with bound manganese and an inhibitor, 2-nitroresorcinol
23% identity, 84% coverage of query (46.6 bits)
GRDC_POLSJ / Q12BV1 Gamma-resorcylate decarboxylase; Gamma-RSD; 2,6-dihydroxybenzoate decarboxylase; 2,6-DHBD; EC 4.1.1.103 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
Q12BV1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Polaromonas sp. JS666 (see paper)
23% identity, 84% coverage of query (46.6 bits)
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Lawrence Berkeley National Laboratory