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Searching for up to 100 curated homologs for H281DRAFT_04085 H281DRAFT_04085 isocitrate dehydrogenase (NADP) (418 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

IDH_PSEAB / Q02NB5 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    78% identity, 100% coverage of query (675 bits)

IDH_COXBU / Q9ZH99 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    76% identity, 100% coverage of query (659 bits)

IcdE / b1136 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
icd / P08200 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli (strain K12) (see 3 papers)
IDH_ECOLI / P08200 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Escherichia coli (strain K12) (see 7 papers)
P08200 [Isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) from Escherichia coli (see paper)
4aj3A / P08200 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and NADP - the pseudo-michaelis complex (see paper)
    76% identity, 98% coverage of query (653 bits)

4ajaA 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp
    76% identity, 98% coverage of query (653 bits)

6c0eA / Q5ZXB6 Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
    75% identity, 100% coverage of query (652 bits)

1bl5A Isocitrate dehydrogenase from e. Coli single turnover laue structure of rate-limited product complex, 10 msec time resolution
    76% identity, 98% coverage of query (652 bits)

1ai3A Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences
    76% identity, 98% coverage of query (652 bits)

1ai2A Isocitrate dehydrogenase complexed with isocitrate, NADP+, and calcium (flash-cooled)
    76% identity, 98% coverage of query (652 bits)

1hj6A Isocitrate dehydrogenase s113e mutant complexed with isopropylmalate, NADP+ and magnesium (flash-cooled)
    76% identity, 98% coverage of query (650 bits)

1idcA Isocitrate dehydrogenase from e.Coli (mutant k230m), steady-state intermediate complex determined by laue crystallography
    76% identity, 98% coverage of query (650 bits)

4ajcA 3d structure of e. Coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate
    76% identity, 98% coverage of query (650 bits)

1cw4A Crystal structure of k230m isocitrate dehydrogenase in complex with alpha-ketoglutarate
    76% identity, 98% coverage of query (650 bits)

1cw1A Crystal structure of isocitrate dehydrogenase mutant k230m bound to isocitrate and mn2+
    76% identity, 98% coverage of query (650 bits)

1groA Regulatory and catalytic mechanisms in escherichia coli isocitrate dehydrogenase: multiple roles for n115
    76% identity, 98% coverage of query (649 bits)

D0Z8Y6 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Edwardsiella tarda (see paper)
    73% identity, 98% coverage of query (642 bits)

1isoA Isocitrate dehydrogenase: structure of an engineered NADP+--> NAD+ specificity-reversal mutant
    75% identity, 98% coverage of query (639 bits)

Q1XIQ8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Colwellia psychrerythraea (see paper)
    74% identity, 99% coverage of query (629 bits)

Q1GZD1 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Methylobacillus flagellatus (see paper)
    71% identity, 99% coverage of query (612 bits)

icd / BAA03135.1 isocitrate dehydrogenase isozyme IDH-I from Colwellia maris (see paper)
    71% identity, 99% coverage of query (609 bits)

icd / B2ZP83 isocitrate dehydrogenase subunit (EC 1.1.1.42) from Helicobacter pylori (see 4 papers)
    70% identity, 98% coverage of query (603 bits)

IDH_BACSU / P39126 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Bacillus subtilis (strain 168) (see paper)
icd / GB|CAB14873.1 isocitrate dehydrogenase; EC 1.1.1.42 from Bacillus subtilis (see 2 papers)
    64% identity, 97% coverage of query (543 bits)

2d4vA / Q8GAX0 Crystal structure of NAD dependent isocitrate dehydrogenase from acidithiobacillus thiooxidans (see paper)
    60% identity, 99% coverage of query (521 bits)

Q8GAX0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Acidithiobacillus thiooxidans (see paper)
    60% identity, 99% coverage of query (521 bits)

2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
    55% identity, 100% coverage of query (447 bits)

A8YGS2 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Microcystis aeruginosa (see paper)
    49% identity, 100% coverage of query (441 bits)

icdh / CAC80860.2 NADP-isocitrate dehydrogenase from Haloferax volcanii (see paper)
    52% identity, 100% coverage of query (435 bits)

IDH_HALVD / D4GU92 Isocitrate dehydrogenase [NADP]; IDH; ICDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    52% identity, 100% coverage of query (434 bits)

Q9HLV8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermoplasma acidophilum (see paper)
    55% identity, 97% coverage of query (423 bits)

icd / Q5UXA4 isocitrate dehydrogenase, NADP (EC 1.1.1.42) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see 4 papers)
    51% identity, 100% coverage of query (410 bits)

Q4J6C9 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Sulfolobus acidocaldarius (see paper)
    49% identity, 94% coverage of query (383 bits)

2e5mA / Q96YK6 Crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain 7 (see paper)
    47% identity, 98% coverage of query (371 bits)

P96318 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Caldococcus noboribetus (see 2 papers)
    50% identity, 94% coverage of query (364 bits)

Q9YE81 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Aeropyrum pernix (see 4 papers)
    46% identity, 99% coverage of query (363 bits)

1tyoA / Q9YE81 Isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in complex with etheno-NADP (see paper)
    46% identity, 99% coverage of query (363 bits)

Q8U488 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Pyrococcus furiosus (see 2 papers)
    48% identity, 99% coverage of query (361 bits)

1xkdA Ternary complex of isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix
    46% identity, 99% coverage of query (355 bits)

icd / Q76LM6 oxalosuccinate reductase subunit from Hydrogenobacter thermophilus (see 3 papers)
    47% identity, 94% coverage of query (349 bits)

6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
    38% identity, 88% coverage of query (210 bits)

2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
    33% identity, 93% coverage of query (190 bits)

P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
    33% identity, 93% coverage of query (190 bits)

aksF / Q58991 NAD-dependent threo-isocitrate dehydrogenase (EC 1.1.1.87) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AKSF_METJA / Q58991 Homoisocitrate dehydrogenase; HICDH; Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase; Isohomocitrate dehydrogenase; IHDH; NAD-dependent threo-isohomocitrate dehydrogenase; EC 1.1.1.87; EC 1.1.1.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58991 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii (see paper)
    30% identity, 87% coverage of query (177 bits)

6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
    33% identity, 86% coverage of query (176 bits)

IDH3A_MOUSE / Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Mus musculus (Mouse) (see paper)
Q9D6R2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Mus musculus (see paper)
    34% identity, 83% coverage of query (174 bits)

6kdeA / P50213 Crystal structure of the alpha beta heterodimer of human idh3 in complex with ca(2+) (see paper)
    32% identity, 91% coverage of query (172 bits)

IDH3A / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3A_HUMAN / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Homo sapiens (Human) (see 5 papers)
P50213 isocitrate dehydrogenase (NAD+) (subunit 2/2) (EC 1.1.1.41) from Homo sapiens (see paper)
    32% identity, 91% coverage of query (172 bits)

6kdyA Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
    33% identity, 83% coverage of query (172 bits)

IDH3A_PIG / P56471 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Sus scrofa (Pig) (see paper)
    32% identity, 91% coverage of query (171 bits)

IDH3A_BOVIN / P41563 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitrate dehydrogenase subunits 3/4; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Bos taurus (Bovine) (see paper)
    33% identity, 83% coverage of query (171 bits)

IDH3A_RAT / Q99NA5 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Rattus norvegicus (Rat) (see paper)
Q99NA5 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rattus norvegicus (see paper)
    33% identity, 83% coverage of query (167 bits)

5yvtA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+) and nadh
    32% identity, 83% coverage of query (166 bits)

8grdA Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
    32% identity, 83% coverage of query (162 bits)

IDH3A_CAEEL / Q93714 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Caenorhabditis elegans (see paper)
    31% identity, 94% coverage of query (160 bits)

6l59A Crystal structure of the alpha gamma heterodimer of human idh3 in complex with cit, mg and atp binding at allosteric site and mg, atp binding at active site.
    31% identity, 83% coverage of query (160 bits)

5greA Crystal structure of the alpha gamma heterodimer of human idh3 in complex with mg(2+), citrate and adp
    32% identity, 83% coverage of query (160 bits)

IDH-V / Q945K7 NAD+-dependent isocitrate dehydrogenase catalytic subunit (EC 1.1.1.286) from Arabidopsis thaliana (see 3 papers)
IDH5_ARATH / Q945K7 Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; IDH-V; Isocitric dehydrogenase 5; NAD(+)-specific ICDH 5; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    31% identity, 87% coverage of query (159 bits)

MJ0720 / Q58130 3-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
LEU3_METJA / Q58130 3-isopropylmalate/3-methylmalate dehydrogenase; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.85; EC 1.1.1.n5; EC 1.1.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    34% identity, 84% coverage of query (156 bits)

IDH-II / P93032 NAD+-dependent isocitrate dehydrogenase regulatory subunit (EC 1.1.1.286) from Arabidopsis thaliana (see paper)
IDH2_ARATH / P93032 Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; IDH-II; Isocitric dehydrogenase 2; NAD(+)-specific ICDH 2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P93032 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    32% identity, 86% coverage of query (155 bits)

idh2 / RF|NP_595203.1 isocitrate dehydrogenase (NAD+) subunit 2; EC 1.1.1.41 from Schizosaccharomyces pombe (see 2 papers)
    30% identity, 87% coverage of query (155 bits)

IDH2_SCHPO / Q9USP8 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
    30% identity, 87% coverage of query (155 bits)

3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
    33% identity, 84% coverage of query (154 bits)

hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
    33% identity, 84% coverage of query (154 bits)

4yb4A Crystal structure of homoisocitrate dehydrogenase from thermus thermophilus in complex with homoisocitrate, magnesium ion (ii) and nadh
    33% identity, 84% coverage of query (154 bits)

3asjB Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
    33% identity, 84% coverage of query (154 bits)

IDH1_ARATH / Q8LFC0 Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; IDH-I; Isocitric dehydrogenase 1; NAD(+)-specific ICDH 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LFC0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
    31% identity, 85% coverage of query (153 bits)

Build an alignment

Build an alignment for H281DRAFT_04085 and 64 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

IDH2 / P28241 isocitrate dehydrogenase [NAD] β subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH2_YEAST / P28241 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P28241 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
    29% identity, 93% coverage of query (152 bits)

G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
    31% identity, 91% coverage of query (150 bits)

IDH3_ARATH / O81796 Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; IDH-III; Isocitric dehydrogenase 3; NAD(+)-specific ICDH 3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O81796 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    31% identity, 86% coverage of query (149 bits)

IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
    30% identity, 87% coverage of query (148 bits)

3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
    29% identity, 93% coverage of query (141 bits)

G1APK2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
    32% identity, 84% coverage of query (140 bits)

LEU3_SULTO / P50455 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
P50455 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Sulfurisphaera tokodaii (see 3 papers)
    28% identity, 84% coverage of query (139 bits)

IDH1_SCHPO / O13696 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
idh1 / RF|NP_594397.1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1; EC 1.1.1.41 from Schizosaccharomyces pombe (see 3 papers)
    30% identity, 93% coverage of query (139 bits)

LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
    29% identity, 85% coverage of query (133 bits)

lysB putative homoisocitrate dehydrogenase from Emericella nidulans (see paper)
    29% identity, 85% coverage of query (133 bits)

HICDH_PYRHO / O59394 Isocitrate/homoisocitrate dehydrogenase; HICDH; Beta-decarboxylating dehydrogenase; EC 1.1.1.286 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
    31% identity, 81% coverage of query (132 bits)

IDH1 / P28834 isocitrate dehydrogenase [NAD] α subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH1_YEAST / P28834 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P28834 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
    30% identity, 87% coverage of query (130 bits)

3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
    30% identity, 87% coverage of query (129 bits)

3blwA Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits
    30% identity, 88% coverage of query (129 bits)

LYS12_SCHPO / O14104 Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.87 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    27% identity, 88% coverage of query (128 bits)

hdh / BAD06515.1 homoisocitrate dehydrogenase, partial from Deinococcus radiodurans (see paper)
    29% identity, 87% coverage of query (128 bits)

3ty3A / O14104 Crystal structure of homoisocitrate dehydrogenase from schizosaccharomyces pombe bound to glycyl-glycyl-glycine (see paper)
    27% identity, 87% coverage of query (127 bits)

4y1pB / Q4JB37 Crystal structure of 3-isopropylmalate dehydrogenase (saci_0600) from sulfolobus acidocaldarius complex with 3-isopropylmalate and mg2+ (see paper)
    27% identity, 82% coverage of query (126 bits)

5hn6A Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and 3-isopropylmalate
    29% identity, 81% coverage of query (115 bits)

5hn4A / Q5JFV8 Crystal structure of beta-decarboxylating dehydrogenase (tk0280) from thermococcus kodakarensis complexed with mn and homoisocitrate (see paper)
    29% identity, 81% coverage of query (115 bits)

6kdyF Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD.
    29% identity, 83% coverage of query (111 bits)

6kdyD / O43837 Crystal structure of the alpha bata heterodimer of human idh3 in complex with NAD. (see paper)
    29% identity, 83% coverage of query (111 bits)

2g4oA / P9WKK9 Anomalous substructure of 3-isopropylmalate dehydrogenase (see paper)
    27% identity, 86% coverage of query (108 bits)

3flkA / Q51945 Crystal structure of tartrate dehydrogenase from pseudomonas putida in complex with nadh, oxalate and metal ion (see paper)
    27% identity, 87% coverage of query (106 bits)

8grdB Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human idh3 in complex with adp and mg
    28% identity, 83% coverage of query (103 bits)

1a05A / Q56268 Crystal structure of the complex of 3-isopropylmalate dehydrogenase from thiobacillus ferrooxidans with 3-isopropylmalate (see paper)
    27% identity, 81% coverage of query (99.0 bits)

LEU3_ACIFR / Q56268 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans) (see 2 papers)
Q56268 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Acidithiobacillus ferrooxidans (see paper)
    27% identity, 81% coverage of query (99.0 bits)

2y42D / Q5SIY4 Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with nadh and mn (see paper)
    26% identity, 86% coverage of query (96.3 bits)

2ztwA Structure of 3-isopropylmalate dehydrogenase in complex with the inhibitor and NAD+
    26% identity, 86% coverage of query (96.3 bits)

LEU3_THET8 / Q5SIY4 3-isopropylmalate dehydrogenase; 3-IPM-DH; Beta-IPM dehydrogenase; IMDH; EC 1.1.1.85 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 4 papers)
Q5SIY4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Thermus thermophilus (see 12 papers)
    26% identity, 86% coverage of query (96.3 bits)

2y41A Structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with ipm and mn
    26% identity, 86% coverage of query (96.3 bits)

6xxyA / P43860 Crystal structure of haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with o-isobutenyl oxalylhydroxamate. (see paper)
    26% identity, 92% coverage of query (94.4 bits)

3vmkA / D2YZL2 3-isopropylmalate dehydrogenase from shewanella benthica db21 mt-2 (see paper)
    27% identity, 85% coverage of query (90.1 bits)

3vkzA / Q8E9N3 3-isopropylmalate dehydrogenase from shewanella oneidensis mr-1 at atmospheric pressure (see paper)
    26% identity, 85% coverage of query (85.9 bits)

4xxvA Crystal structure of 3-isopropylmalate dehydrogenase from burkholderia thailandensis in complex with NAD
    26% identity, 92% coverage of query (85.5 bits)

4iwhA / Q2T7H6 Crystal structure of a 3-isopropylmalate dehydrogenase from burkholderia pseudomallei
    26% identity, 92% coverage of query (85.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory