Sites on a Tree

 

Searching for up to 100 curated homologs for H281DRAFT_04094 FitnessBrowser__Burk376:H281DRAFT_04094 (744 a.a.)

Found high-coverage hits (≥70%) to 7 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.5.26 / P63395 Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318, component of The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis from Mycobacterium tuberculosis (see 2 papers)
    40% identity, 81% coverage of query (377 bits)

GsiA / b0829 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiA / P75796 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli (strain K12) (see 3 papers)
GSIA_ECOLI / P75796 Glutathione import ATP-binding protein GsiA; EC 7.4.2.10 from Escherichia coli (strain K12) (see paper)
P75796 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75796 Hypothetical ABC transporter ATP-binding protein yliA, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
    36% identity, 84% coverage of query (369 bits)

TC 3.A.1.5.8 / Q97UG5 MalK, component of Maltose and maltooligosaccharide porter from Sulfolobus solfataricus (see paper)
    36% identity, 78% coverage of query (354 bits)

Build an alignment

Build an alignment for H281DRAFT_04094 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

8buu9 / W1SM44 8buu9 (see paper)
    24% identity, 77% coverage of query (94.7 bits)

YBP8_SCHPO / O42943 Uncharacterized ABC transporter ATP-binding protein C16H5.08c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    23% identity, 81% coverage of query (86.7 bits)

ARB1_YEAST / P40024 ABC transporter ATP-binding protein ARB1; ATP-binding cassette protein involved in ribosome biogenesis 1; EC 3.6.5.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    23% identity, 78% coverage of query (82.8 bits)

VMLR_BACSU / P39115 Ribosome protection protein VmlR; Multidrug resistance system ATP-binding protein VmlR from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.121.3 / P39115 Antibiotic (virginiamycin and lincomycin) resistance protein, VmlR from Bacillus subtilis (see paper)
    24% identity, 70% coverage of query (75.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory