Searching for up to 100 curated homologs for H281DRAFT_04843 FitnessBrowser__Burk376:H281DRAFT_04843 (310 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
34% identity, 100% coverage of query (190 bits)
GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
37% identity, 98% coverage of query (170 bits)
F2NQX6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Marinithermus hydrothermalis (see paper)
33% identity, 99% coverage of query (160 bits)
7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
35% identity, 98% coverage of query (159 bits)
galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
35% identity, 98% coverage of query (159 bits)
7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
35% identity, 98% coverage of query (159 bits)
7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
35% identity, 98% coverage of query (159 bits)
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
32% identity, 96% coverage of query (154 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
32% identity, 96% coverage of query (154 bits)
fcfA / Q6E7F2 dTDP-4-dehydro-6-deoxyglucose reductase [NAD(P)H] (EC 1.1.1.266) from Escherichia coli (see 2 papers)
FCF1_ECOLX / Q6E7F2 dTDP-4-dehydro-6-deoxyglucose reductase; dTDP-4-dehydro-6-deoxy-D-glucose reductase; dTDP-4-keto-6-deoxyglucose reductase; dTDP-6-deoxy-D-xylo-hex-4-ulopyranose reductase; EC 1.1.1.266 from Escherichia coli (see paper)
30% identity, 98% coverage of query (150 bits)
2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
35% identity, 99% coverage of query (150 bits)
F6DEY6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Thermus thermophilus (see paper)
34% identity, 99% coverage of query (149 bits)
galE / CAA89986.1 UDP-galactose 4-epimease from Corynebacterium glutamicum (see paper)
34% identity, 94% coverage of query (138 bits)
epsS / BAC55147.1 UDP-glucose 4-epimerase EpsS from Methylobacillus sp. 12S (see paper)
32% identity, 98% coverage of query (136 bits)
O73960 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrococcus horikoshii (see paper)
34% identity, 75% coverage of query (124 bits)
Build an alignment for H281DRAFT_04843 and 15 homologs with ≥ 30% identity
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6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
28% identity, 99% coverage of query (122 bits)
uxe / Q92WA3 UDP-xylose 4-epimerase subunit (EC 5.1.3.5) from Rhizobium meliloti (strain 1021) (see paper)
Q92WA3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Sinorhizobium meliloti (see paper)
31% identity, 99% coverage of query (122 bits)
1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
30% identity, 98% coverage of query (122 bits)
GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
30% identity, 98% coverage of query (121 bits)
N0A422 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 100% coverage of query (121 bits)
2udpA Udp-galactose 4-epimerase complexed with udp-phenol
30% identity, 98% coverage of query (121 bits)
1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
30% identity, 98% coverage of query (121 bits)
1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
30% identity, 98% coverage of query (121 bits)
1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
30% identity, 98% coverage of query (121 bits)
1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
30% identity, 98% coverage of query (121 bits)
1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
29% identity, 98% coverage of query (120 bits)
uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
27% identity, 98% coverage of query (120 bits)
N0A414 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 99% coverage of query (120 bits)
N0A8N8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 99% coverage of query (119 bits)
Q5D9E1 UDP-glucose 4-epimerase (EC 5.1.3.2) from Schistosoma japonicum (see paper)
29% identity, 99% coverage of query (119 bits)
N0A8N3 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 99% coverage of query (119 bits)
N0A0C4 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
27% identity, 99% coverage of query (119 bits)
2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
26% identity, 99% coverage of query (118 bits)
Q9SN95 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
27% identity, 99% coverage of query (118 bits)
Q9ZV36 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
28% identity, 99% coverage of query (118 bits)
UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
26% identity, 99% coverage of query (118 bits)
UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
26% identity, 99% coverage of query (118 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
29% identity, 99% coverage of query (117 bits)
Q8W3J1 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-4 / BAB84333.2 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
28% identity, 98% coverage of query (117 bits)
UXS2 / Q9LZI2 subunit of UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 3 papers)
UXS2_ARATH / Q9LZI2 UDP-glucuronic acid decarboxylase 2; UDP-XYL synthase 2; UDP-glucuronate decarboxylase 2; UGD; UXS-2; dTDP-glucose 4-6-dehydratase homolog D18; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LZI2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
27% identity, 99% coverage of query (116 bits)
UXS1 / Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
UXS1_ARATH / Q8VZC0 UDP-glucuronic acid decarboxylase 1; UDP-XYL synthase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
26% identity, 99% coverage of query (116 bits)
UXS3 / Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 2 papers)
UXS3_ARATH / Q9FIE8 UDP-glucuronic acid decarboxylase 3; UDP-XYL synthase 3; UDP-glucuronate decarboxylase 3; UGD; UXS-3; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
26% identity, 100% coverage of query (116 bits)
Q8W3J0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-3 / BAB84334.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
26% identity, 100% coverage of query (115 bits)
fcd / A2BD24 dTDP-4-dehydro-6-deoxyglucose reductase (EC 1.1.1.266) from Anoxybacillus tepidamans (see paper)
26% identity, 96% coverage of query (115 bits)
A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
32% identity, 97% coverage of query (114 bits)
Q75PK7 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-2 / BAD12490.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
28% identity, 99% coverage of query (114 bits)
3eheA / O29886 Crystal structure of udp-glucose 4 epimerase (gale-1) from archaeoglobus fulgidus
32% identity, 96% coverage of query (114 bits)
UDPGlcADCX1 / Q6IVK5 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Nicotiana tabacum (see paper)
26% identity, 99% coverage of query (113 bits)
Q9AV98 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Pisum sativum (see paper)
uxs1 / BAB40967.1 UDP-D-glucuronate carboxy-lyase from Pisum sativum (see paper)
27% identity, 99% coverage of query (113 bits)
UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
25% identity, 99% coverage of query (112 bits)
galE / P21977 UDP-glucose-4-epimerase (EC 5.1.3.2) from Streptococcus thermophilus (see paper)
GALE_STRTR / P21977 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Streptococcus thermophilus (see paper)
P21977 UDP-glucose 4-epimerase (EC 5.1.3.2) from Streptococcus thermophilus (see paper)
32% identity, 98% coverage of query (112 bits)
4twrA / Q2YKG6 Structure of udp-glucose 4-epimerase from brucella abortus
31% identity, 96% coverage of query (112 bits)
2c20A / A0A6L8PTV5 Crystal structure of udp-glucose 4-epimerase
29% identity, 98% coverage of query (111 bits)
Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
28% identity, 96% coverage of query (110 bits)
GALE_LACHE / Q7WTB1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Lactobacillus helveticus (Lactobacillus suntoryeus) (see paper)
28% identity, 99% coverage of query (110 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
31% identity, 97% coverage of query (110 bits)
UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
27% identity, 98% coverage of query (110 bits)
galE / P55180 UDP-glucose 4-epimerase (EC 5.1.3.7; EC 5.1.3.2) from Bacillus subtilis (strain 168) (see 5 papers)
galE / CAA67713.1 UDP-glucose 4-epimerase from Bacillus subtilis (see paper)
29% identity, 100% coverage of query (110 bits)
A0A0H2UQY4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Streptococcus pneumoniae (see paper)
28% identity, 97% coverage of query (110 bits)
1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
28% identity, 96% coverage of query (110 bits)
galE / CAB44218.1 UDP-galactose 4-epimerase from Lactococcus lactis (see paper)
30% identity, 100% coverage of query (109 bits)
Q75PK6 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-1 / BAD12491.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
26% identity, 99% coverage of query (108 bits)
tunF / E5KJ99 UDP-6-deoxy-5,6-ene-GlcNAc 4-epimerase (EC 5.1.3.7) from Streptomyces chartreusis (see paper)
28% identity, 98% coverage of query (107 bits)
C6K2L0 GDP-mannose 3,5-epimerase (EC 5.1.3.18) from Solanum lycopersicum (see paper)
28% identity, 100% coverage of query (107 bits)
wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
28% identity, 96% coverage of query (107 bits)
2q1sA / O87989 Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with nadh (see paper)
29% identity, 99% coverage of query (106 bits)
2pzjA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+
29% identity, 99% coverage of query (105 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
26% identity, 100% coverage of query (104 bits)
2q1tA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+ and udp
29% identity, 99% coverage of query (104 bits)
2cnbA Trypanosoma brucei udp-galactose-4-epimerase in ternary complex with NAD and the substrate analogue udp-4-deoxy-4- fluoro-alpha-d-galactose
29% identity, 100% coverage of query (103 bits)
1gy8C / Q8T8E9 Trypanosoma brucei udp-galactose 4' epimerase (see paper)
29% identity, 100% coverage of query (102 bits)
6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
25% identity, 97% coverage of query (102 bits)
GALE / Q14376 UDP-galactose 4-epimerase (EC 5.1.3.2; EC 5.1.3.7) from Homo sapiens (see 6 papers)
GALE_HUMAN / Q14376 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Homo sapiens (Human) (see 12 papers)
Q14376 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Homo sapiens (see 4 papers)
30% identity, 95% coverage of query (102 bits)
6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
25% identity, 97% coverage of query (102 bits)
1ek6A Structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
30% identity, 95% coverage of query (102 bits)
7xpqA Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glcnac
29% identity, 97% coverage of query (100 bits)
7xpoA / C0HI30 Crystal structure of udp-glc/glcnac 4-epimerase with NAD/udp-glc (see paper)
29% identity, 97% coverage of query (100 bits)
7kn1A / B2FNY6 Crystal structure of udp-glucose-4-epimerase (gale) from stenotrophomonas maltophila with bound NAD and formylated udp- arabinopyranose
30% identity, 99% coverage of query (100 bits)
1i3lA Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase
30% identity, 95% coverage of query (100 bits)
1i3kA / Q14376 Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase (see paper)
30% identity, 95% coverage of query (100 bits)
2pzmA / O87988 Crystal structure of the bordetella bronchiseptica enzyme wbmg in complex with NAD and udp (see paper)
29% identity, 98% coverage of query (100 bits)
1hzjA Human udp-galactose 4-epimerase: accommodation of udp-n- acetylglucosamine within the active site
30% identity, 95% coverage of query (100 bits)
6k0iA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glc
30% identity, 98% coverage of query (99.4 bits)
6k0hA Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp-glcnac
30% identity, 98% coverage of query (99.4 bits)
6k0gA / E8MF10 Crystal structure of udp-glucose 4-epimerase from bifidobacterium longum in complex with NAD+ and udp (see paper)
30% identity, 98% coverage of query (99.4 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
27% identity, 94% coverage of query (99.0 bits)
wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
30% identity, 82% coverage of query (99.0 bits)
2c59A / Q93VR3 Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha- d-mannose and gdp-beta-l-galactose bound in the active site. (see paper)
26% identity, 100% coverage of query (98.2 bits)
GME / Q93VR3 GDP-D-mannose-3,5-epimerase (EC 5.1.3.18) from Arabidopsis thaliana (see paper)
GME_ARATH / Q93VR3 GDP-mannose 3,5-epimerase; GDP-Man 3,5-epimerase; EC 5.1.3.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
26% identity, 100% coverage of query (97.8 bits)
3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
30% identity, 82% coverage of query (97.8 bits)
3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
30% identity, 82% coverage of query (97.8 bits)
3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
30% identity, 82% coverage of query (97.8 bits)
2c54A Gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp- beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site.
25% identity, 100% coverage of query (97.1 bits)
6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
29% identity, 99% coverage of query (95.5 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
26% identity, 98% coverage of query (95.1 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
26% identity, 98% coverage of query (95.1 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
26% identity, 98% coverage of query (95.1 bits)
GALE_CAEEL / Q564Q1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Caenorhabditis elegans (see paper)
28% identity, 95% coverage of query (95.1 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
29% identity, 99% coverage of query (94.7 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
26% identity, 98% coverage of query (94.0 bits)
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Lawrence Berkeley National Laboratory