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Searching for up to 100 curated homologs for H281DRAFT_05212 FitnessBrowser__Burk376:H281DRAFT_05212 (429 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ABAQ_ACIBT / P0DPR4 Quinolone resistance transporter from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) (see 2 papers)
    30% identity, 95% coverage of query (184 bits)

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Build an alignment for H281DRAFT_05212 and 1 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 2.A.1.14.8 / Q9RPP3 Phthalate porter from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
    28% identity, 94% coverage of query (152 bits)

BWI76_RS23715 2-deoxy-D-ribonate transporter 1 from Klebsiella michiganensis M5al
    26% identity, 93% coverage of query (143 bits)

PS417_07265 2-deoxy-D-ribonate transporter 1 from Pseudomonas simiae WCS417
    28% identity, 87% coverage of query (143 bits)

NICT_PSEPK / Q88FY6 Putative metabolite transport protein NicT; Nicotinate degradation protein T from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    27% identity, 95% coverage of query (138 bits)

BPHYT_RS04765 2-deoxy-D-ribonate transporter from Burkholderia phytofirmans PsJN
    27% identity, 89% coverage of query (128 bits)

YfaV / b2246 putative transporter YfaV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TC 2.A.1.14.35 / P76470 Inner membrane transport protein RhmT from Escherichia coli (strain K12) (see 4 papers)
    26% identity, 95% coverage of query (123 bits)

CH_124132 transporter of Nicotinic Acid from Magnaporthe grisea 70-15 (see paper)
    29% identity, 85% coverage of query (122 bits)

orf19.3232 putative transporter from Candida albicans (see paper)
    25% identity, 85% coverage of query (117 bits)

GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
    25% identity, 95% coverage of query (114 bits)

SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
    25% identity, 98% coverage of query (114 bits)

H281DRAFT_00642 2-deoxy-D-ribonate transporter from Paraburkholderia bryophila 376MFSha3.1
    24% identity, 91% coverage of query (113 bits)

YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
    24% identity, 95% coverage of query (113 bits)

6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
    25% identity, 95% coverage of query (112 bits)

AO356_28540 D-mannose transporter from Pseudomonas fluorescens FW300-N2C3
    25% identity, 93% coverage of query (110 bits)

CH_124318 MFS transporter from Magnaporthe grisea 70-15 (see 2 papers)
    28% identity, 73% coverage of query (107 bits)

ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
    23% identity, 86% coverage of query (107 bits)

PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
    24% identity, 96% coverage of query (107 bits)

CH_124319 high-affinity nicotinic acid transporter from Magnaporthe grisea 70-15 (see paper)
    24% identity, 78% coverage of query (105 bits)

YIZG_SCHPO / Q9US44 Uncharacterized transporter C1002.16c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    24% identity, 72% coverage of query (104 bits)

ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    24% identity, 87% coverage of query (103 bits)

6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
    25% identity, 95% coverage of query (102 bits)

GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP.  Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
    22% identity, 95% coverage of query (97.8 bits)

CH_124316 allantoate permease from Magnaporthe grisea 70-15 (see paper)
    23% identity, 92% coverage of query (93.6 bits)

GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
    23% identity, 96% coverage of query (92.0 bits)

TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
    23% identity, 96% coverage of query (92.0 bits)

ANTR6_ARATH / Q3E9A0 Probable anion transporter 6, chloroplastic; Phosphate transporter PHT4;5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    24% identity, 86% coverage of query (82.8 bits)

TC 2.A.1.14.26 / F2YPN7 The plasma membrane Lethal (2)01810 glutamate uptake porter (Km=0.07μM) (Inhibited by aspartate) from Drosophila melanogaster
    22% identity, 80% coverage of query (81.3 bits)

TNA1 putative nicotinic acid transporter from Candida albicans (see paper)
    24% identity, 76% coverage of query (81.3 bits)

S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
    25% identity, 94% coverage of query (79.0 bits)

S17A9_RAT / P0DX21 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Rattus norvegicus (Rat) (see 2 papers)
    24% identity, 96% coverage of query (76.6 bits)

PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
    22% identity, 73% coverage of query (76.3 bits)

S17A9_HUMAN / Q9BYT1 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Homo sapiens (Human) (see 4 papers)
TC 2.A.1.14.21 / Q9BYT1 The vesicular purine nucleotide (ADP, ATP, GTP) transporter, VNUT or SLC17A9. It is found in synaptic vesicles and chromafin granules (Sawada et al., 2008)) and is associated with disseminated superficial actinic porokeratosis (DSAP), a rare autosomal dominant genodermatosis (Cui et al. 2014). It plays a key role in purinergic signaling through its ability to transport nucleotides using the pmf. It catalyzes Cl--dependent transport activity involving essential arginines in the transmembrane region. Ketoacids inhibit these transporters through modulation of Cl- activation, but Cl- and the arginine residues are not important for ATP binding (Iwai et al. 2019). High expression of SLC17A9 correlates with a poor prognosis for colorectal cancer from Homo sapiens (Human) (see 5 papers)
    24% identity, 88% coverage of query (75.5 bits)

VGLU2_RAT / Q9JI12 Vesicular glutamate transporter 2; VGluT2; Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 6 from Rattus norvegicus (Rat) (see 10 papers)
TC 2.A.1.14.16 / Q9JI12 The broad specificity brain synaptic vesicle anion transporter (transports glutamate in a Δψ-dependent fashion requiring Cl- but phosphate by a Na+-dependent mechanism via a different pathway/mechanism from Rattus norvegicus (see 8 papers)
    22% identity, 88% coverage of query (68.9 bits)

7t3nA / Q9JI12 R184q/e191q mutant of rat vesicular glutamate transporter 2 (vglut2)
    21% identity, 86% coverage of query (66.2 bits)

P53322 High-affinity nicotinic acid transporter; Nicotinic acid permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    21% identity, 76% coverage of query (57.4 bits)

MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
    22% identity, 97% coverage of query (57.0 bits)

YaiK / b0353 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpT / P77589 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
MHPT_ECOLI / P77589 3-(3-hydroxy-phenyl)propionate transporter; 3HPP transporter; 3-(3-hydroxy-phenyl)propionate:H(+) symporter; 3HPP:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.15.2 / P77589 MhpT. A specific 3-(3-hydroxyphenyl)propionate (3HPP) transporter; vital for E. coli K-12 W3110 to grow on this substrate from Escherichia coli (see 3 papers)
    24% identity, 79% coverage of query (45.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory