Sites on a Tree

 

Searching for up to 100 curated homologs for H281DRAFT_05269 FitnessBrowser__Burk376:H281DRAFT_05269 (328 a.a.)

Found high-coverage hits (≥70%) to 39 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

6hbdA / A0QT50 Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with beta-d-galactofuranose (see paper)
    59% identity, 89% coverage of query (362 bits)

6hyhA Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with beta-d-fucofuranose
    59% identity, 89% coverage of query (362 bits)

6hbmA Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with alpha-l-arabinofuranose
    59% identity, 89% coverage of query (362 bits)

Shewana3_2073 L-arabinose ABC transporter, substrate-binding component AraU from Shewanella sp. ANA-3
    50% identity, 95% coverage of query (296 bits)

5ocpA / A0KWY4 The periplasmic binding protein component of the arabinose abc transporter from shewanella sp. Ana-3 bound to alpha and beta-l- arabinofuranose
    53% identity, 88% coverage of query (294 bits)

2vk2A / P39325 Crystal structure of a galactofuranose binding protein (see paper)
    49% identity, 88% coverage of query (275 bits)

YtfQ / b4227 galactofuranose ABC transporter periplasmic binding protein (EC 7.5.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
YtfQ / P39325 galactofuranose ABC transporter periplasmic binding protein (EC 7.5.2.9) from Escherichia coli (strain K12) (see 3 papers)
YTFQ_ECOLI / P39325 Galactofuranose-binding protein YtfQ from Escherichia coli (strain K12) (see paper)
P39325 ABC-type D-galactofuranose transporter (EC 7.5.2.9) from Escherichia coli (see paper)
    49% identity, 88% coverage of query (274 bits)

FRUE_BIFLO / Q8G848 Fructose import binding protein FruE from Bifidobacterium longum (strain NCC 2705) (see paper)
    33% identity, 92% coverage of query (147 bits)

2ioyA / Q8RD41 Crystal structure of thermoanaerobacter tengcongensis ribose binding protein (see paper)
    33% identity, 75% coverage of query (119 bits)

Build an alignment

Build an alignment for H281DRAFT_05269 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

RBSB_BACSU / P36949 Ribose import binding protein RbsB from Bacillus subtilis (strain 168) (see 2 papers)
    27% identity, 86% coverage of query (111 bits)

2x7xA / Q8A6X1 Fructose binding periplasmic domain of hybrid two component system bt1754 (see paper)
    29% identity, 87% coverage of query (105 bits)

8fxuA / D9TSJ1 Thermoanaerobacter thermosaccharolyticum periplasmic glucose-binding protein glucose complex: badan conjugate attached at f17c (see paper)
    30% identity, 73% coverage of query (97.1 bits)

7e7mC / Q8E283 Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
    29% identity, 86% coverage of query (96.3 bits)

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    29% identity, 81% coverage of query (93.6 bits)

TC 3.A.1.2.13 / A6VKT0 RbsB, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    29% identity, 74% coverage of query (92.4 bits)

4rsmA / A0QYB5 Crystal structure of carbohydrate transporter msmeg_3599 from mycobacterium smegmatis str. Mc2 155, target efi-510970, in complex with d-threitol (see paper)
    29% identity, 81% coverage of query (92.4 bits)

4zjpA / A6VKT0 Structure of an abc-transporter solute binding protein (sbp_ipr025997) from actinobacillus succinogenes (asuc_0197, target efi-511067) with bound beta-d-ribopyranose
    29% identity, 74% coverage of query (92.0 bits)

2fn8A / Q9X053 Thermotoga maritima ribose binding protein ribose bound form (see paper)
    30% identity, 74% coverage of query (88.6 bits)

TC 3.A.1.2.19 / Q9X053 Periplasmic binding protein/LacI transcriptional regulator, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    30% identity, 74% coverage of query (88.2 bits)

HSERO_RS05260 ABC transporter for L-fucose, substrate-binding component from Herbaspirillum seropedicae SmR1
    26% identity, 89% coverage of query (66.2 bits)

TC 3.A.1.2.21 / B8H228 Inositol ABC transporter, periplasmic inositol-binding protein IbpA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    25% identity, 72% coverage of query (65.1 bits)

4irxA / A0A0H3C834 Crystal structure of caulobacter myo-inositol binding protein bound to myo-inositol (see paper)
    25% identity, 72% coverage of query (64.7 bits)

APIBP_PARG4 / B1G898 D-apiose import binding protein; D-apiose binding SBP from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
    29% identity, 70% coverage of query (62.0 bits)

6gt9A / W8QN64 Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with galactose
    22% identity, 80% coverage of query (62.0 bits)

6guqA Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with glucose
    22% identity, 80% coverage of query (62.0 bits)

B9K0Q5 ABC-type D-galactose transporter (EC 7.5.2.11) from Agrobacterium vitis (see paper)
    27% identity, 74% coverage of query (60.1 bits)

4y9tA / B9K0Q5 Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis s4 (avi_5305, target efi-511224) with bound alpha-d-glucosamine (see paper)
    27% identity, 74% coverage of query (59.7 bits)

5br1A Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis s4 (avi_5305, target efi-511224) with bound alpha-d-galactosamine
    27% identity, 74% coverage of query (59.3 bits)

4ry9A / A1WJM2 Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    26% identity, 78% coverage of query (58.9 bits)

4ry9B Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    26% identity, 78% coverage of query (58.9 bits)

PGA1_262p00430 glucose transporter, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    26% identity, 72% coverage of query (52.4 bits)

4ys6A / A9KQP6 Crystal structure of an abc transporter solute binding protein (ipr025997) from clostridium phytofermentans (cphy_1585, target efi- 511156) with bound beta-d-glucose
    23% identity, 73% coverage of query (50.8 bits)

CcpA / VIMSS824262 CcpA regulator of Carbon catabolism, effector HPr, phosphocarrier protein from Bacillus clausii KSM-K16
    23% identity, 71% coverage of query (50.8 bits)

2jcgA Apo form of the catabolite control protein a (ccpa) from bacillus megaterium, with the DNA binding domain
    24% identity, 77% coverage of query (48.1 bits)

CcpA / P46828 Transcription factor CcpA (repressor) from Bacillus megaterium (see 3 papers)
1rzrG / P46828 Crystal structure of transcriptional regulator- phosphoprotein-DNA complex (see paper)
ccpA / AAA22295.1 catabolite control protein from Bacillus megaterium (see paper)
    23% identity, 77% coverage of query (46.6 bits)

1rzrA Crystal structure of transcriptional regulator- phosphoprotein-DNA complex
    23% identity, 77% coverage of query (46.6 bits)

1sxgB Structural studies on the apo transcription factor form b. Megaterium
    23% identity, 77% coverage of query (46.6 bits)

2nzvG Structural mechanism for the fine-tuning of ccpa function by the small molecule effectors g6p and fbp
    23% identity, 77% coverage of query (46.2 bits)

2nzuG Structural mechanism for the fine-tuning of ccpa function by the small molecule effectors g6p and fbp
    23% identity, 77% coverage of query (46.2 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory