Sites on a Tree

 

Searching for up to 100 curated homologs for H281DRAFT_05622 FitnessBrowser__Burk376:H281DRAFT_05622 (442 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AZOBR_RS08020 D-alanine dehydrogenase (EC 1.4.99.-) from Azospirillum brasilense Sp245
    44% identity, 100% coverage of query (375 bits)

DadR / b1189 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dadA / P0A6J5 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli (strain K12) (see 22 papers)
DADA_ECOLI / P0A6J5 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Escherichia coli (strain K12) (see 4 papers)
dadA / AAC36880.1 D-amino acid dehydrogenase from Escherichia coli (see paper)
    42% identity, 100% coverage of query (356 bits)

DADA1_PSEAE / Q9HTQ0 D-amino acid dehydrogenase 1; D-alanine dehydrogenase 1; EC 1.4.99.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9HTQ0 D-arginine dehydrogenase (EC 1.4.99.6) from Pseudomonas aeruginosa (see paper)
    41% identity, 100% coverage of query (355 bits)

Psest_3793 D-alanine dehydrogenase (EC 1.4.99.-) from Pseudomonas stutzeri RCH2
    40% identity, 100% coverage of query (353 bits)

DADA_KLEAE / O30745 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Klebsiella aerogenes (Enterobacter aerogenes) (see paper)
    41% identity, 100% coverage of query (333 bits)

Ac3H11_4848 D-alanine dehydrogenase (EC 1.4.99.-) from Acidovorax sp. GW101-3H11
    35% identity, 98% coverage of query (268 bits)

RR42_RS25930 glycine dehydrogenase (deaminating) (EC 1.4.1.10) from Cupriavidus basilensis FW507-4G11
    30% identity, 96% coverage of query (178 bits)

Build an alignment

Build an alignment for H281DRAFT_05622 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

dadA / A3KEZ1 D-amino acid dehydrogenase (EC 1.4.5.1) from Helicobacter pylori (see paper)
DADA_HELPX / A3KEZ1 D-amino acid dehydrogenase; DAD; EC 1.4.5.1 from Helicobacter pylori (Campylobacter pylori) (see paper)
A3KEZ1 D-amino acid dehydrogenase (quinone) (EC 1.4.5.1); D-arginine dehydrogenase (EC 1.4.99.6) from Helicobacter pylori (see 2 papers)
    22% identity, 93% coverage of query (101 bits)

amaD / Q88GX1 D-lysine oxidase (EC 1.4.3.3) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    24% identity, 99% coverage of query (99.0 bits)

lhpB / Q88NF6 D-hydroxyproline dehydrogenase subunit from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    26% identity, 95% coverage of query (85.5 bits)

6j38A / X5IYZ1 Crystal structure of cmis2 (see paper)
    28% identity, 74% coverage of query (54.3 bits)

6j39A Crystal structure of cmis2 with inhibitor
    28% identity, 74% coverage of query (54.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory