Sites on a Tree

 

Searching for up to 100 curated homologs for H281DRAFT_05886 FitnessBrowser__Burk376:H281DRAFT_05886 (213 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YcgS / b1199 dihydroxyacetone kinase subunit L (EC 2.7.1.121) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
dhaL / P76014 dihydroxyacetone kinase subunit L (EC 2.7.1.121) from Escherichia coli (strain K12) (see 12 papers)
DHAL_ECOLI / P76014 PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL; EC 2.7.1.121 from Escherichia coli (strain K12) (see 6 papers)
P76014 phosphoenolpyruvate-glycerone phosphotransferase (subunit 3/3) (EC 2.7.1.121); glycerone kinase (EC 2.7.1.29) from Escherichia coli (see 4 papers)
dhaL PTS-dependent dihydroxyacetone kinase, DhaL subunit; EC 2.7.-.-; EC 2.7.1.- from Escherichia coli K12 (see 7 papers)
    37% identity, 84% coverage of query (109 bits)

4lrzA / P76014 Crystal structure of the e.Coli dhar(n)-dhal complex (see paper)
    37% identity, 84% coverage of query (109 bits)

3cr3A / Q9CIV7 Structure of a transient complex between dha-kinase subunits dham and dhal from lactococcus lactis (see paper)
    34% identity, 95% coverage of query (103 bits)

DHAL_LACLA / Q9CIV7 PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL; EC 2.7.1.121 from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) (see paper)
    34% identity, 95% coverage of query (103 bits)

G0LLJ4 glycerone kinase (subunit 1/2) (EC 2.7.1.29) from Haloquadratum walsbyi (see paper)
    33% identity, 95% coverage of query (94.4 bits)

DHAL2_LISIN / Q92EU3 PEP-dependent dihydroxyacetone kinase 2, ADP-binding subunit DhaL; EC 2.7.1.121 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
    31% identity, 91% coverage of query (87.4 bits)

B9LNV9 glycerone kinase (subunit 1/2) (EC 2.7.1.29) from Halorubrum lacusprofundi (see paper)
    33% identity, 81% coverage of query (80.9 bits)

Build an alignment

Build an alignment for H281DRAFT_05886 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

A0A1D3TV19 glycerone kinase (EC 2.7.1.29) from Anaerobium acetethylicum (see paper)
    27% identity, 95% coverage of query (68.6 bits)

A0A0H3J0E7 glycerone kinase (EC 2.7.1.29) from Clostridium pasteurianum (see paper)
    27% identity, 90% coverage of query (65.5 bits)

Q8VC30 triokinase (EC 2.7.1.28) from Mus musculus (see paper)
    30% identity, 82% coverage of query (59.7 bits)

DAK1 / P54838 dihydroxyacetone kinase 1 (EC 2.7.1.29) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
DAK1_YEAST / P54838 Dihydroxyacetone kinase 1; DHA kinase 1; Glycerone kinase 1; Triokinase 1; Triose kinase 1; EC 2.7.1.28; EC 2.7.1.29 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P54838 glycerone kinase (EC 2.7.1.29) from Saccharomyces cerevisiae (see paper)
    28% identity, 79% coverage of query (59.3 bits)

Dak / Q4KLZ6 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) (EC 2.7.1.29; EC 4.6.1.15) from Rattus norvegicus (see 3 papers)
TKFC_RAT / Q4KLZ6 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Rattus norvegicus (Rat) (see 2 papers)
    30% identity, 87% coverage of query (57.8 bits)

TKFC / Q3LXA3 bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) (EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15) from Homo sapiens (see paper)
TKFC_HUMAN / Q3LXA3 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Homo sapiens (Human) (see 5 papers)
Q3LXA3 triokinase (EC 2.7.1.28); glycerone kinase (EC 2.7.1.29); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) from Homo sapiens (see 5 papers)
    30% identity, 82% coverage of query (50.4 bits)

TKFC_PIG / F1RKQ4 Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); EC 2.7.1.28; EC 2.7.1.29; EC 4.6.1.15 from Sus scrofa (Pig) (see paper)
    31% identity, 79% coverage of query (48.1 bits)

DAK / O60017 dihydroxyacetone kinase subunit (EC 2.7.1.29) from Pichia angusta (see 2 papers)
    26% identity, 88% coverage of query (47.0 bits)

lerK / A0R758 L-erythrulose 1-kinase (EC 2.7.1.209) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 2 papers)
LERK_MYCS2 / A0R758 L-erythrulose 1-kinase; EC 2.7.1.209 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
A0R758 L-erythrulose 1-kinase (EC 2.7.1.209) from Mycolicibacterium smegmatis (see paper)
    27% identity, 95% coverage of query (46.6 bits)

LERK_PECAS / Q6D8V6 L-erythrulose kinase; EC 2.7.1.209 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
    28% identity, 92% coverage of query (45.8 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory