Searching for up to 100 curated homologs for H281DRAFT_06348 FitnessBrowser__Burk376:H281DRAFT_06348 (452 a.a.)
Found high-coverage hits (≥70%) to 40 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
proT / BAB32694.1 putative transporter from Pseudomonas straminea (see 2 papers)
60% identity, 94% coverage of query (516 bits)
PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
48% identity, 95% coverage of query (396 bits)
PCAK_ACIAD / Q43975 4-hydroxybenzoate transporter PcaK; 4-HB transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
45% identity, 92% coverage of query (384 bits)
GALT_PSEPU / E8ZB61 Gallate transporter; Gallate permease from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
galT / CBJ94499.1 gallic acid permease from Pseudomonas putida (see paper)
46% identity, 87% coverage of query (338 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
41% identity, 98% coverage of query (317 bits)
Build an alignment for H281DRAFT_06348 and 5 homologs with ≥ 30% identity
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TC 2.A.1.15.5 / O30513 Benzoate porter, BenK from Acinetobacter calcoaceticus (see 2 papers)
28% identity, 99% coverage of query (203 bits)
TC 2.A.1.15.7 / Q6FBB3 Aromatic compound (benzoate) uptake transporter of 450 aas from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
29% identity, 96% coverage of query (190 bits)
TC 2.A.1.15.6 / O24842 Vanillate porter, VanK (see 4 papers)
29% identity, 91% coverage of query (182 bits)
TC 2.A.1.15.3 / Q46M63 2,4-Dichlorophenoxyacetate porter (see 5 papers)
32% identity, 82% coverage of query (176 bits)
TC 2.A.1.15.14 / Q8VUZ0 Probable uptake transporter for 2,4-dichlorophenoxyacetic acid (2,4-D), CadK from Bradyrhizobium sp. HW13
29% identity, 92% coverage of query (174 bits)
YaiK / b0353 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpT / P77589 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
MHPT_ECOLI / P77589 3-(3-hydroxy-phenyl)propionate transporter; 3HPP transporter; 3-(3-hydroxy-phenyl)propionate:H(+) symporter; 3HPP:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.15.2 / P77589 MhpT. A specific 3-(3-hydroxyphenyl)propionate (3HPP) transporter; vital for E. coli K-12 W3110 to grow on this substrate from Escherichia coli (see 3 papers)
31% identity, 91% coverage of query (171 bits)
NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
27% identity, 93% coverage of query (157 bits)
TC 2.A.1.15.11 / Q6M372 The Vanillate porter, VanK from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
28% identity, 97% coverage of query (155 bits)
TC 2.A.1.15.8 / O24723 Probable 1-hydroxy-2-naphthoate transporter, orf1 (see paper)
28% identity, 88% coverage of query (154 bits)
NIAP_BACSU / O34691 Putative niacin/nicotinamide transporter NiaP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.82.4 / O34691 Niacin uptake porter NiaP from Bacillus subtilis (see 2 papers)
28% identity, 90% coverage of query (124 bits)
genK / Q8NLB7 gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
GENK_CORGL / Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
29% identity, 80% coverage of query (121 bits)
SVOP_XENLA / Q2XWK0 Synaptic vesicle 2-related protein; SV2-related protein from Xenopus laevis (African clawed frog) (see paper)
25% identity, 85% coverage of query (103 bits)
SVOP_BOVIN / Q1JP63 Synaptic vesicle 2-related protein; SV2-related protein from Bos taurus (Bovine) (see paper)
25% identity, 85% coverage of query (102 bits)
NanT / b3224 N-acetylneuraminate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
nanT / P41036 N-acetylneuraminate:H+ symporter from Escherichia coli (strain K12) (see 16 papers)
NANT_ECOLI / P41036 Sialic acid transporter NanT; Sialic acid permease; Sialic acid/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.12.1 / P41036 The sialic acid porter, NanT. N-acetylneuraminic acid (Neu5Ac) serves as a sole source of carbon and nitrogen for E. coli. It is a mucus-derived carbon source in the mammalian gut. NanT can also take up and allow efficient growth on the related sialic acids, N-glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-d-glycero-d-galactonononic acid (KDN) from Escherichia coli (see 4 papers)
26% identity, 85% coverage of query (91.3 bits)
TC 2.A.1.82.3 / Q8BFT9 Synaptic vesicle 2-related protein (SV2-related protein), SVOP from Mus musculus (see 4 papers)
24% identity, 90% coverage of query (89.4 bits)
SVOP_RAT / Q9Z2I7 Synaptic vesicle 2-related protein; SV2-related protein from Rattus norvegicus (Rat) (see paper)
24% identity, 85% coverage of query (87.0 bits)
TC 2.A.1.15.4 / P94131 cis,cis-muconate porter, MucK from Acinetobacter calcoaceticus (see 2 papers)
mucK / AAC27117.1 cis,cis-muconate transport protein MucK from Acinetobacter baylyi (see paper)
24% identity, 79% coverage of query (85.9 bits)
TC 2.A.1.1.116 / C4B4V9 Arabinose/xylose transporter, AraE from Corynebacterium glutamicum
24% identity, 96% coverage of query (82.8 bits)
TC 2.A.1.82.1 / F2CRE4 The barley copper uptake porter, CT-1 of 749 aas; nearly identical to the wheat orthologue from Hordeum vulgare var. distichum
24% identity, 89% coverage of query (72.0 bits)
TC 2.A.1.1.53 / Q8NTX0 Myo-Inositol uptake porter, IolT1 (Km=0.2mM) from Corynebacterium glutamicum (Brevibacterium flavum) (see paper)
26% identity, 71% coverage of query (70.9 bits)
YdjK / b1775 putative transporter YdjK from Escherichia coli K-12 substr. MG1655 (see 3 papers)
27% identity, 74% coverage of query (69.3 bits)
TC 2.A.1.1.42 / Q8G3X1 The D-glucose:H+ symporter, GlcP (glucose uptake is inhibited by 2-deoxyglucose, mannose and galactose) from Bifidobacterium longum (see paper)
27% identity, 82% coverage of query (67.4 bits)
4gc0A The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose
26% identity, 78% coverage of query (57.8 bits)
4gbzA The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose
26% identity, 78% coverage of query (57.8 bits)
4gbyA / P0AGF4 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose (see paper)
26% identity, 78% coverage of query (57.8 bits)
XylE / b4031 D-xylose:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 7 papers)
xylE / P0AGF4 D-xylose:H+ symporter from Escherichia coli (strain K12) (see 8 papers)
XYLE_ECOLI / P0AGF4 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) (see paper)
TC 2.A.1.1.3 / P0AGF4 Xylose (xylopyranose):H+ symporter of 491 aas and 12 TMSs from Escherichia coli (see 7 papers)
xylE D-xylose-proton symporter from Escherichia coli K12 (see 7 papers)
26% identity, 78% coverage of query (57.8 bits)
6zguA Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
25% identity, 88% coverage of query (49.7 bits)
6zgtA Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
25% identity, 88% coverage of query (49.7 bits)
6zgsA / A0LNN5 Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
25% identity, 88% coverage of query (49.7 bits)
S22A5_HUMAN / O76082 Organic cation/carnitine transporter 2; High-affinity sodium-dependent carnitine cotransporter; Solute carrier family 22 member 5 from Homo sapiens (Human) (see 28 papers)
TC 2.A.1.19.3 / O76082 The polyspecific organic cation (L- and D-carnitine, butyryl-L-carnitine, acetyl carnitine, γ-butyro-betaine, glycinebetaine, β-lactam antibiotics with a quaternary nitrogen such as cephaloridine, and others):Na+ symporter, OCTN2 (SLC22A5). Carnitine is transporter with high affinity (2 - 20 μM0 (Ingoglia et al. 2015). Associated with Crohn''s disease (Barton et al., 2005) as well as primary carnitine deficiency from Homo sapiens (Human) (see 28 papers)
25% identity, 81% coverage of query (47.4 bits)
8et8A Cryo-em structure of the organic cation transporter 1 in complex with verapamil
23% identity, 85% coverage of query (45.4 bits)
8et7A / O15245 Cryo-em structure of the organic cation transporter 1 in complex with diphenhydramine (see paper)
23% identity, 85% coverage of query (45.4 bits)
SFMCT_SYNFM / A0LNN5 L-lactate transporter; SfMCT from Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) (see paper)
24% identity, 87% coverage of query (45.1 bits)
6zgrA Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
24% identity, 88% coverage of query (44.7 bits)
S22A2_HUMAN / O15244 Solute carrier family 22 member 2; Organic cation transporter 2; hOCT2 from Homo sapiens (Human) (see 25 papers)
TC 2.A.1.19.30 / O15244 Solute carrier family 22 member 2 (Organic cation transporter 2) (hOCT2) from Homo sapiens (see 23 papers)
23% identity, 75% coverage of query (44.7 bits)
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Lawrence Berkeley National Laboratory