Searching for up to 100 curated homologs for HSERO_RS00880 FitnessBrowser__HerbieS:HSERO_RS00880 (312 a.a.)
Found high-coverage hits (≥70%) to 31 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PYCR1_BURM1 / A9AKH1 Delta(1)-pyrroline-2-carboxylate reductase 1; Pyr2C reductase 1; Proline ketimine reductase 1; EC 1.5.1.49 from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
44% identity, 99% coverage of query (197 bits)
PYCR2_BURCM / Q0B953 Delta(1)-pyrroline-2-carboxylate reductase 2; Pyr2C reductase 2; Proline ketimine reductase 2; EC 1.5.1.49 from Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) (see paper)
45% identity, 98% coverage of query (184 bits)
lhpI / V5YW53 Δ1-pyrroline-2-carboxylate reductase subunit (EC 1.5.1.49) from Azospirillum brasilense (see paper)
PY2CR_AZOBR / V5YW53 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase; Pyr2C/Pip2C reductase; EC 1.5.1.1 from Azospirillum brasilense (see paper)
V5YW53 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] (EC 1.5.1.1) from Azospirillum brasilense (see paper)
44% identity, 90% coverage of query (171 bits)
Q9QYU4 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Rattus norvegicus (see paper)
30% identity, 88% coverage of query (108 bits)
F1RPC8 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Sus scrofa (see paper)
30% identity, 89% coverage of query (108 bits)
O54983 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Mus musculus (see paper)
30% identity, 88% coverage of query (106 bits)
Build an alignment for HSERO_RS00880 and 6 homologs with ≥ 30% identity
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W5PYW4 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Ovis aries (see paper)
29% identity, 88% coverage of query (102 bits)
4bv9A Crystal structure of the NADPH form of mouse mu-crystallin.
30% identity, 88% coverage of query (102 bits)
CRYM / Q14894 ketimine reductase monomer (EC 1.5.1.1; EC 1.5.1.25) from Homo sapiens (see 9 papers)
CRYM_HUMAN / Q14894 Ketimine reductase mu-crystallin; NADP-regulated thyroid-hormone-binding protein; EC 1.5.1.25 from Homo sapiens (Human) (see 3 papers)
Q14894 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21); thiomorpholine-carboxylate dehydrogenase (EC 1.5.1.25) from Homo sapiens (see 2 papers)
29% identity, 88% coverage of query (101 bits)
2i99A / Q14894 Crystal structure of human mu_crystallin at 2.6 angstrom (see paper)
29% identity, 88% coverage of query (101 bits)
PY2CR_BACCZ / Q63FA5 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Bacillus cereus (strain ZK / E33L) (see paper)
27% identity, 95% coverage of query (98.6 bits)
4bvaA Crystal structure of the NADPH-t3 form of mouse mu-crystallin.
30% identity, 88% coverage of query (98.2 bits)
PY2CR_BACHK / Q6HMS8 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Bacillus thuringiensis subsp. konkukian (strain 97-27) (see paper)
26% identity, 95% coverage of query (96.7 bits)
PY2CR_BACC1 / Q73CR9 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Bacillus cereus (strain ATCC 10987 / NRS 248) (see paper)
26% identity, 95% coverage of query (96.3 bits)
6t3eB / H3ZMH3 Structure of thermococcus litoralis delta(1)-pyrroline-2-carboxylate reductase in complex with nadh and l-proline (see paper)
24% identity, 98% coverage of query (91.7 bits)
PY2CR_BACCR / Q81HB0 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
25% identity, 95% coverage of query (90.5 bits)
YK01_SCHPO / Q9HDZ0 Uncharacterized protein P11E10.01 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 96% coverage of query (89.0 bits)
PY2CR_COLP3 / Q485R8 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) (see 2 papers)
Q485R8 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] (EC 1.5.1.1) from Colwellia psychrerythraea (see paper)
25% identity, 97% coverage of query (81.3 bits)
SARD4_ARATH / Q9FLY0 Protein SAR DEFICIENT 4; Ornithine cyclodeaminase-like protein; AtOCD from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
28% identity, 79% coverage of query (75.5 bits)
1omoA / O28608 Alanine dehydrogenase dimer w/bound NAD (archaeal) (see paper)
27% identity, 97% coverage of query (70.5 bits)
ALADH_ARCFU / O28608 Alanine dehydrogenase; AlaDH; EC 1.4.1.1 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 2 papers)
O28608 alanine dehydrogenase (EC 1.4.1.1) from Archaeoglobus fulgidus (see paper)
27% identity, 97% coverage of query (70.1 bits)
B1GT63 Strombine dehydrogenase (EC 1.5.1.22) from Suberites domuncula (see paper)
24% identity, 79% coverage of query (56.6 bits)
tadh / Q60FC7 tauropine dehydrogenase (EC 1.5.1.23) from Halichondria japonica (see 2 papers)
23% identity, 79% coverage of query (56.2 bits)
arcB / J7SH14 ornithine cyclodeaminase subunit (EC 4.3.1.12) from Clostridium sporogenes (strain ATCC 15579) (see 2 papers)
24% identity, 83% coverage of query (52.8 bits)
6rqaA / A1B8Z0 Crystal structure of the iminosuccinate reductase of paracoccus denitrificans in complex with NAD+ (see paper)
27% identity, 75% coverage of query (52.0 bits)
BHCD_PARDP / A1B8Z0 Iminosuccinate reductase; EC 1.4.1.- from Paracoccus denitrificans (strain Pd 1222) (see paper)
27% identity, 75% coverage of query (52.0 bits)
6rqaB Crystal structure of the iminosuccinate reductase of paracoccus denitrificans in complex with NAD+
27% identity, 75% coverage of query (52.0 bits)
5gzlA / D9UBW0 Cyclodeaminase_pa
29% identity, 80% coverage of query (49.7 bits)
5gziA Cyclodeaminase_pa
29% identity, 80% coverage of query (49.7 bits)
5yu4A Structural basis for recognition of l-lysine, l-ornithine, and l-2,4- diamino butyric acid by lysine cyclodeaminase
29% identity, 80% coverage of query (49.3 bits)
5yu3A Structural basis for recognition of l-lysine, l-ornithine, and l-2,4- diamino butyric acid by lysine cyclodeaminase
29% identity, 80% coverage of query (49.3 bits)
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Lawrence Berkeley National Laboratory