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Searching for up to 100 curated homologs for HSERO_RS01485 FitnessBrowser__HerbieS:HSERO_RS01485 (280 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
    55% identity, 99% coverage of query (318 bits)

4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
    55% identity, 99% coverage of query (318 bits)

YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
    53% identity, 95% coverage of query (293 bits)

4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
    54% identity, 98% coverage of query (286 bits)

6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
    54% identity, 98% coverage of query (285 bits)

Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
    39% identity, 91% coverage of query (171 bits)

6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
    39% identity, 91% coverage of query (171 bits)

5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
    39% identity, 91% coverage of query (171 bits)

6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
    39% identity, 91% coverage of query (171 bits)

Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis (see paper)
    38% identity, 88% coverage of query (145 bits)

Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see 2 papers)
    38% identity, 88% coverage of query (142 bits)

A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    34% identity, 92% coverage of query (127 bits)

1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
    31% identity, 93% coverage of query (126 bits)

PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
    31% identity, 93% coverage of query (125 bits)

Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
    32% identity, 93% coverage of query (122 bits)

4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
    32% identity, 93% coverage of query (122 bits)

4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
    32% identity, 93% coverage of query (121 bits)

2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
    31% identity, 94% coverage of query (118 bits)

Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    31% identity, 94% coverage of query (118 bits)

3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
    33% identity, 91% coverage of query (117 bits)

A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
    32% identity, 93% coverage of query (114 bits)

PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
    31% identity, 93% coverage of query (111 bits)

4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
    31% identity, 93% coverage of query (111 bits)

Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
    31% identity, 93% coverage of query (110 bits)

Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    31% identity, 93% coverage of query (109 bits)

3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
    32% identity, 93% coverage of query (109 bits)

yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
    32% identity, 93% coverage of query (109 bits)

E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
    32% identity, 92% coverage of query (107 bits)

Build an alignment

Build an alignment for HSERO_RS01485 and 28 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
    28% identity, 98% coverage of query (106 bits)

8jwkD The second purified state crystal structure of akrtyl
    35% identity, 94% coverage of query (106 bits)

8jwoL / A0A3R7J519 Crystal structure of akrtyl-tylosin complex (see paper)
    34% identity, 94% coverage of query (105 bits)

1vp5A / Q9X0A2 Crystal structure of 2,5-diketo-d-gluconic acid reductase (tm1009) from thermotoga maritima at 2.40 a resolution
    31% identity, 94% coverage of query (105 bits)

PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
    29% identity, 83% coverage of query (105 bits)

8jwkH The second purified state crystal structure of akrtyl
    34% identity, 94% coverage of query (105 bits)

YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
    30% identity, 95% coverage of query (104 bits)

akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
    31% identity, 93% coverage of query (103 bits)

Q5DD64 aldose reductase (EC 1.1.1.21) from Schistosoma japonicum (see paper)
    27% identity, 93% coverage of query (102 bits)

AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
    29% identity, 93% coverage of query (102 bits)

AKR1C4 / P17516 aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.357) from Homo sapiens (see 9 papers)
AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human) (see 11 papers)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens (see 4 papers)
    31% identity, 93% coverage of query (100 bits)

AK1A1_RAT / P51635 Aldo-keto reductase family 1 member A1; 3-DG-reducing enzyme; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Rattus norvegicus (Rat) (see 4 papers)
P51635 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Rattus norvegicus (see 2 papers)
    28% identity, 92% coverage of query (100 bits)

5az1A Crystal structure of aldo-keto reductase (akr2e5) complexed with nadph (see paper)
    29% identity, 98% coverage of query (100 bits)

GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
    29% identity, 92% coverage of query (100 bits)

2fvlA / P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (akr1c4) complexed with NADP+
    31% identity, 93% coverage of query (100 bits)

8jwmB / A0A3R7J519 Crystal structure of akrtyl-NADP-tylosin complex (see paper)
    33% identity, 94% coverage of query (99.8 bits)

AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
    29% identity, 93% coverage of query (99.8 bits)

4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
    31% identity, 93% coverage of query (98.6 bits)

3ufyA Akr1c3 complex with r-naproxen
    31% identity, 93% coverage of query (98.6 bits)

3r94A Akr1c3 complex with flurbiprofen
    31% identity, 93% coverage of query (98.6 bits)

3r8hA Akr1c3 complex with zomepirac
    31% identity, 93% coverage of query (98.6 bits)

3r8gA Akr1c3 complex with ibuprofen
    31% identity, 93% coverage of query (98.6 bits)

3r7mA Akr1c3 complex with sulindac
    31% identity, 93% coverage of query (98.6 bits)

3r6iA Akr1c3 complex with meclofenamic acid
    31% identity, 93% coverage of query (98.6 bits)

4wdxA 17beta-hsd5 in complex with [4-(2-hydroxyethyl)piperidin-1-yl](5- methyl-1h-indol-2-yl)methanone
    31% identity, 93% coverage of query (98.6 bits)

3r58A Akr1c3 complex with naproxen
    31% identity, 93% coverage of query (98.6 bits)

7x3oA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07054
    31% identity, 93% coverage of query (98.2 bits)

4hmnA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (4-(4-chlorophenyl)piperazin-1-yl)(morpholino) methanone (24)
    31% identity, 93% coverage of query (98.2 bits)

4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
    31% identity, 93% coverage of query (98.2 bits)

Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
    28% identity, 92% coverage of query (97.8 bits)

AKR1A1 / P50578 aldehyde reductase (EC 1.1.1.2) from Sus scrofa (see paper)
AK1A1_PIG / P50578 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Sus scrofa (Pig) (see paper)
P50578 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Sus scrofa (see 2 papers)
3fx4A / P50578 Porcine aldehyde reductase in ternary complex with inhibitor (see paper)
    28% identity, 92% coverage of query (97.8 bits)

4h7cA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 1-{4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl}-2- pyrrolidinone
    31% identity, 93% coverage of query (97.8 bits)

DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
    28% identity, 89% coverage of query (97.4 bits)

3cv7A Crystal structure of porcine aldehyde reductase ternary complex
    28% identity, 92% coverage of query (97.4 bits)

3h4gA Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
    28% identity, 92% coverage of query (97.4 bits)

DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
    29% identity, 93% coverage of query (97.1 bits)

1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
    29% identity, 92% coverage of query (97.1 bits)

YPR1_YEAST / Q12458 Putative reductase 1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 86% coverage of query (97.1 bits)

3r43A Akr1c3 complexed with mefenamic acid
    30% identity, 93% coverage of query (96.7 bits)

8rb6A Structure of aldo-keto reductase 1c3 (akr1c3) in complex with an inhibitor m689, with the 3-hydroxy-benzoisoxazole moiety. Resolution 2.0a
    30% identity, 93% coverage of query (96.7 bits)

4wdwA 17beta-hsd5 in complex with 3,6-dihydropyridin-1(2h)-yl(5-methyl-1h- indol-2-yl)methanone
    30% identity, 93% coverage of query (96.7 bits)

AK1CN_HORSE / Q1XAA8 Aldo-keto reductase family 1 member C23; EC 1.1.1.- from Equus caballus (Horse) (see paper)
Q1XAA8 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Equus caballus (see paper)
    29% identity, 93% coverage of query (96.3 bits)

Q95JH5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see paper)
    30% identity, 93% coverage of query (96.3 bits)

eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
    31% identity, 83% coverage of query (96.3 bits)

AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
    28% identity, 91% coverage of query (95.9 bits)

Q5FYA7 prostaglandin-F synthase (EC 1.1.1.188) from Canis lupus familiaris (see 2 papers)
    30% identity, 92% coverage of query (95.9 bits)

D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
    27% identity, 93% coverage of query (95.5 bits)

G1T465 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239) from Oryctolagus cuniculus (see paper)
    29% identity, 92% coverage of query (95.5 bits)

3uweA Akr1c3 complexed with 3-phenoxybenzoic acid
    30% identity, 93% coverage of query (95.5 bits)

AK1A1_HUMAN / P14550 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Homo sapiens (Human) (see 4 papers)
    27% identity, 92% coverage of query (95.1 bits)

8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
    31% identity, 89% coverage of query (95.1 bits)

YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
    26% identity, 91% coverage of query (94.7 bits)

Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
    26% identity, 93% coverage of query (94.7 bits)

AK1C4_MACFU / Q95JH4 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase homolog; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Macaca fuscata fuscata (Japanese macaque) (see paper)
    29% identity, 93% coverage of query (94.7 bits)

3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
    26% identity, 93% coverage of query (94.7 bits)

1zq5A Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor em1404
    30% identity, 93% coverage of query (94.4 bits)

GCY1 putative uncharacterized protein from Candida albicans (see paper)
    29% identity, 93% coverage of query (94.0 bits)

AK1BA_HUMAN / O60218 Aldo-keto reductase family 1 member B10; ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase; EC 1.1.1.300; EC 1.1.1.54 from Homo sapiens (Human) (see 7 papers)
O60218 aldose reductase (EC 1.1.1.21) from Homo sapiens (see 2 papers)
    29% identity, 91% coverage of query (94.0 bits)

AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
    29% identity, 89% coverage of query (94.0 bits)

4gq0A / O60218 Crystal structure of akr1b10 complexed with NADP+ and caffeic acid phenethyl ester
    29% identity, 91% coverage of query (94.0 bits)

AK1CO_HORSE / Q6W8P9 Aldo-keto reductase family 1 member C23-like protein; Putative prostaglandin F synthase; EC 1.1.1.- from Equus caballus (Horse) (see paper)
    29% identity, 92% coverage of query (94.0 bits)

H9CWC0 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) (EC 1.1.1.274) from Corynebacterium glutamicum (see paper)
    30% identity, 93% coverage of query (94.0 bits)

4gabA Human akr1b10 mutant v301l complexed with NADP+ and fidarestat
    29% identity, 91% coverage of query (94.0 bits)

4ga8A Human akr1b10 mutant v301l complexed with NADP+ and sorbinil
    29% identity, 91% coverage of query (94.0 bits)

4jiiX Crystal structure of akr1b10 complexed with NADP+ and zopolrestat
    29% identity, 91% coverage of query (94.0 bits)

4jihA Crystal structure of akr1b10 complexed with NADP+ and epalrestat
    29% identity, 91% coverage of query (94.0 bits)

1zuaX Crystal structure of akr1b10 complexed with NADP+ and tolrestat
    29% identity, 91% coverage of query (94.0 bits)

1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
    29% identity, 93% coverage of query (94.0 bits)

4xvdA 17beta-hsd5 in complex with 4-nitro-2-({4-[3-(trifluoromethyl) phenyl]piperazin-1-yl}methyl)phenol
    30% identity, 93% coverage of query (94.0 bits)

5m2fX Crystal structure of human akr1b10 complexed with NADP+ and the synthetic retinoid uvi2008
    29% identity, 91% coverage of query (94.0 bits)

5liyX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk204
    29% identity, 91% coverage of query (94.0 bits)

5lixX Crystal structure of human akr1b10 complexed with NADP+ and the inhibitor mk184
    29% identity, 91% coverage of query (94.0 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory