Sites on a Tree

 

Searching for up to 100 curated homologs for HSERO_RS02180 FitnessBrowser__HerbieS:HSERO_RS02180 (301 a.a.)

Found high-coverage hits (≥70%) to 70 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pf6N2E2_1965 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E2
    49% identity, 99% coverage of query (288 bits)

AO356_00035 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2C3
    49% identity, 99% coverage of query (286 bits)

BPHYT_RS02045 Fructokinase (EC 2.7.1.4) from Burkholderia phytofirmans PsJN
    47% identity, 97% coverage of query (239 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    33% identity, 94% coverage of query (105 bits)

PfGW456L13_3036 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens GW456-L13
    31% identity, 93% coverage of query (103 bits)

Build an alignment

Build an alignment for HSERO_RS02180 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    29% identity, 98% coverage of query (103 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    29% identity, 94% coverage of query (102 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    30% identity, 98% coverage of query (100 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    30% identity, 98% coverage of query (99.0 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    30% identity, 98% coverage of query (99.0 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    30% identity, 95% coverage of query (97.8 bits)

AO353_25910 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E3
    30% identity, 93% coverage of query (97.1 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    30% identity, 86% coverage of query (95.9 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    29% identity, 94% coverage of query (95.5 bits)

4wjmA / Q2YNY7 Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
    30% identity, 92% coverage of query (94.7 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    30% identity, 96% coverage of query (94.4 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    28% identity, 98% coverage of query (94.0 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    28% identity, 98% coverage of query (92.8 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    27% identity, 96% coverage of query (92.4 bits)

frk / GB|AAB52373.1 fructokinase; EC 2.7.1.4 from Rhizobium leguminosarum bv. trifolii (see paper)
    31% identity, 82% coverage of query (92.4 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    28% identity, 98% coverage of query (92.0 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    27% identity, 98% coverage of query (91.7 bits)

N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
    31% identity, 96% coverage of query (90.5 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    28% identity, 97% coverage of query (90.5 bits)

scrK / P26420 fructokinase (EC 2.7.1.4) from Klebsiella pneumoniae (see paper)
SCRK_KLEPN / P26420 Fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / GB|CAA43322.1 fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / CAA43322.1 fructokinase from Klebsiella pneumoniae (see paper)
    31% identity, 82% coverage of query (90.1 bits)

3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
    26% identity, 93% coverage of query (89.7 bits)

3ih0A / O59128 Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
    26% identity, 93% coverage of query (89.4 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    27% identity, 84% coverage of query (89.0 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    26% identity, 96% coverage of query (89.0 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    29% identity, 84% coverage of query (88.2 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    29% identity, 84% coverage of query (85.5 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    29% identity, 84% coverage of query (85.5 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    25% identity, 94% coverage of query (85.1 bits)

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    31% identity, 88% coverage of query (84.3 bits)

1v1aA / Q53W83 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
    31% identity, 88% coverage of query (84.3 bits)

1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp
    31% identity, 88% coverage of query (84.3 bits)

Sama_0561 Fructokinase (EC 2.7.1.4) from Shewanella amazonensis SB2B
    27% identity, 95% coverage of query (83.6 bits)

scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    28% identity, 83% coverage of query (79.3 bits)

3lkiB / Q87CC0 Crystal structure of fructokinase with bound atp from xylella fastidiosa
    30% identity, 97% coverage of query (79.0 bits)

Ac3H11_3034 Fructokinase (EC 2.7.1.4) from Acidovorax sp. GW101-3H11
    31% identity, 84% coverage of query (77.0 bits)

Shewana3_0069 Fructokinase (EC 2.7.1.4) from Shewanella sp. ANA-3
    29% identity, 82% coverage of query (73.6 bits)

scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
    24% identity, 83% coverage of query (71.6 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    26% identity, 93% coverage of query (70.5 bits)

A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
    27% identity, 81% coverage of query (69.7 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    27% identity, 81% coverage of query (69.7 bits)

iolC / P42414 5-dehydro-2-deoxy-D-gluconate kinase (EC 2.7.1.92) from Bacillus subtilis (strain 168) (see 2 papers)
IOLC_BACSU / P42414 5-dehydro-2-deoxygluconokinase; 2-deoxy-5-keto-D-gluconate kinase; DKG kinase; EC 2.7.1.92 from Bacillus subtilis (strain 168) (see paper)
    24% identity, 89% coverage of query (67.8 bits)

5yggA / A0A0H3AER7 Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
    27% identity, 81% coverage of query (67.8 bits)

CCNA_01356 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Caulobacter crescentus NA1000
iolC-DUF2090 / A0A0H3C6B4 bifunctional 5-dehydro-2-deoxygluconokinase/5-dehydro-2-deoxyphosphogluconate aldolase (EC 2.7.1.92; EC 4.1.2.29) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 3 papers)
    22% identity, 90% coverage of query (65.5 bits)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    29% identity, 87% coverage of query (62.0 bits)

BPHYT_RS13910 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Burkholderia phytofirmans PsJN
    25% identity, 85% coverage of query (58.9 bits)

7fcaD / B2HEF4 Pfkb(mycobacterium marinum) (see paper)
    28% identity, 93% coverage of query (58.2 bits)

7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
    25% identity, 89% coverage of query (56.6 bits)

C4M2I2 fructokinase (EC 2.7.1.4) from Entamoeba histolytica (see paper)
    25% identity, 87% coverage of query (55.8 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    27% identity, 92% coverage of query (55.1 bits)

7ag6A / P32143 Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
    24% identity, 89% coverage of query (53.5 bits)

SquV / b3883 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yihV / P32143 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli (strain K12) (see 2 papers)
SQUV_ECOLI / P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see 2 papers)
    24% identity, 89% coverage of query (53.5 bits)

7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp)
    24% identity, 89% coverage of query (53.5 bits)

BWI76_RS03085 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Klebsiella michiganensis M5al
    22% identity, 85% coverage of query (51.2 bits)

KDGK1_HALVD / D4GSE6 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxygluconate/2-keto-3-deoxygalactonate kinase; KDG kinase; KDGK-1; EC 2.7.1.178 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GSE6 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Haloferax volcanii (see paper)
    24% identity, 76% coverage of query (50.4 bits)

Pf6N2E2_512 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) from Pseudomonas fluorescens FW300-N2E2
    24% identity, 84% coverage of query (50.4 bits)

BT2804 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    26% identity, 74% coverage of query (50.4 bits)

G4T023 fructokinase (EC 2.7.1.4) from Methylotuvimicrobium alcaliphilum (see paper)
    26% identity, 93% coverage of query (50.1 bits)

YhjI / b3526 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178; EC 2.7.1.45) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
kdgK / P37647 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178) from Escherichia coli (strain K12) (see 4 papers)
KDGK_ECOLI / P37647 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain K12) (see paper)
    24% identity, 89% coverage of query (47.0 bits)

BPHYT_RS25805 deoxyribose kinase (EC 2.7.1.15) from Burkholderia phytofirmans PsJN
    24% identity, 90% coverage of query (46.2 bits)

6a8cA Ribokinase from leishmania donovani with adp
    26% identity, 75% coverage of query (45.8 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    26% identity, 75% coverage of query (45.8 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    26% identity, 75% coverage of query (45.8 bits)

HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
    24% identity, 78% coverage of query (45.4 bits)

4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
    24% identity, 98% coverage of query (43.1 bits)

2dcnA / Q96XN9 Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
    23% identity, 84% coverage of query (42.7 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory