Searching for up to 100 curated homologs for HSERO_RS04630 HSERO_RS04630 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (254 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4o5oB / A0A0H3G6B0 X-ray crystal structure of a 3-hydroxyacyl-coa dehydrogenase from brucella suis
61% identity, 100% coverage of query (303 bits)
fadB2x / Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
61% identity, 100% coverage of query (293 bits)
4xgnA / Q2T0K5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase in complex with NAD from burkholderia thailandensis
58% identity, 100% coverage of query (275 bits)
HSD17B10 / Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35; EC 1.1.1.178; EC 1.1.1.239) from Homo sapiens (see 3 papers)
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Homo sapiens (Human) (see 22 papers)
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Homo sapiens (see 2 papers)
53% identity, 99% coverage of query (249 bits)
7onuC Structure of human mitochondrial rnase p in complex with mitochondrial pre-tRNA-tyr
53% identity, 99% coverage of query (249 bits)
1u7tA Crystal structure of abad/hsd10 with a bound inhibitor
53% identity, 99% coverage of query (248 bits)
HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxyacyl-CoA dehydrogenase type II; Hydroxysteroid dehydrogenase; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.62; EC 1.1.1.-; EC 1.1.1.53 from Drosophila melanogaster (Fruit fly) (see 4 papers)
52% identity, 98% coverage of query (247 bits)
O70351 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Rattus norvegicus (Rat)
51% identity, 99% coverage of query (239 bits)
1e3wD / O70351 Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and 3-keto butyrate (see paper)
51% identity, 99% coverage of query (238 bits)
6ujkA / P9WGQ7 Crystal structure of a probable short-chain type dehydrogenase/reductase (rv1144) from mycobacterium tuberculosis with bound NAD
51% identity, 100% coverage of query (235 bits)
2o23B / Q99714 The structure of wild-type human hadh2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 a
52% identity, 99% coverage of query (235 bits)
HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.62; EC 1.1.1.239; EC 1.1.1.178; EC 1.1.1.53; EC 1.1.1.159 from Mus musculus (Mouse) (see paper)
51% identity, 99% coverage of query (235 bits)
1uayA / Q7SIA1 Crystal structure of type ii 3-hydroxyacyl-coa dehydrogenase from thermus thermophilus hb8
55% identity, 81% coverage of query (234 bits)
1e6wC Rat brain 3-hydroxyacyl-coa dehydrogenase binary complex with nadh and estradiol
50% identity, 99% coverage of query (228 bits)
7n09A / F1L0H2 Structural basis for branched substrate selectivity in a ketoreductase from ascaris suum
50% identity, 97% coverage of query (225 bits)
3ppiA / A0A0H3A4S5 Crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from mycobacterium avium (see paper)
42% identity, 97% coverage of query (187 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
38% identity, 98% coverage of query (143 bits)
IDOLDH / G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see paper)
IDLDH_IPSPI / G5DGA8 Ipsdienol dehydrogenase; EC 1.1.1.386 from Ips pini (Pine engraver beetle) (see paper)
G5DGA8 ipsdienol dehydrogenase (EC 1.1.1.386) from Ips pini (see 2 papers)
33% identity, 98% coverage of query (130 bits)
SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
39% identity, 99% coverage of query (129 bits)
4cqlI / Q92506 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD (see paper)
33% identity, 98% coverage of query (114 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
33% identity, 97% coverage of query (113 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
33% identity, 97% coverage of query (113 bits)
7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
36% identity, 95% coverage of query (113 bits)
BWI76_RS23705 2-deoxy-D-ribonyl-CoA 3-dehydrogenase from Klebsiella michiganensis M5al
35% identity, 95% coverage of query (112 bits)
4cqmA Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP
34% identity, 98% coverage of query (112 bits)
HSD17B8 / Q92506 estradiol 17β-dehydrogenase 8 (EC 1.1.1.100) from Homo sapiens (see 4 papers)
DHB8_HUMAN / Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; HSD17B8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke6; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Homo sapiens (Human) (see 5 papers)
Q92506 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Homo sapiens (see paper)
33% identity, 98% coverage of query (110 bits)
PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
33% identity, 98% coverage of query (108 bits)
4wecA / A0QVJ7 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis
33% identity, 96% coverage of query (106 bits)
gutD / CAA05517.1 glucitol-6-phosphate dehydrogenase from Clostridium beijerinckii (see paper)
32% identity, 91% coverage of query (106 bits)
BWI76_RS01745 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) from Klebsiella michiganensis M5al
32% identity, 94% coverage of query (105 bits)
4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
35% identity, 96% coverage of query (104 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
31% identity, 96% coverage of query (103 bits)
fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
30% identity, 96% coverage of query (103 bits)
5itvD / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
32% identity, 97% coverage of query (103 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 96% coverage of query (102 bits)
Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
32% identity, 96% coverage of query (101 bits)
DHB8_RAT / Q6MGB5 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Rattus norvegicus (Rat) (see paper)
32% identity, 99% coverage of query (100 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
32% identity, 99% coverage of query (100 bits)
4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
31% identity, 96% coverage of query (100 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
30% identity, 98% coverage of query (100 bits)
CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
31% identity, 96% coverage of query (100 bits)
baiA3 / P07914 3α-hydroxysteroyl-CoA 3-dehydrogenase monomer (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 8 papers)
BAIA1_CLOSV / P07914 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 1/3; 3alpha-hydroxysteroid dehydrogenase 1/3; 3alpha-HSDH 1/3; Bile acid-inducible protein BaiA1; Bile acid-inducible protein BaiA3; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
31% identity, 98% coverage of query (100 bits)
A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) from Arthrobacter sp. TS-15 (see paper)
30% identity, 98% coverage of query (100 bits)
6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
30% identity, 98% coverage of query (100 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
32% identity, 99% coverage of query (99.8 bits)
A0JC04 octanol dehydrogenase (EC 1.1.1.73) from Ogataea wickerhamii (see paper)
31% identity, 95% coverage of query (99.0 bits)
G3XRE5 gluconate 5-dehydrogenase (EC 1.1.1.69) from Aspergillus niger (see paper)
32% identity, 94% coverage of query (97.8 bits)
5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
32% identity, 96% coverage of query (97.8 bits)
Build an alignment for HSERO_RS04630 and 48 homologs with ≥ 30% identity
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budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
28% identity, 97% coverage of query (97.1 bits)
badH / O07457 BadH from Rhodopseudomonas palustris (see paper)
31% identity, 96% coverage of query (97.1 bits)
uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 95% coverage of query (96.7 bits)
1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
32% identity, 95% coverage of query (96.3 bits)
PGDH_MOUSE / Q8VCC1 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; Prostaglandin dehydrogenase 1; EC 1.1.1.141; EC 1.1.1.-; EC 1.1.1.232 from Mus musculus (Mouse) (see 2 papers)
Q8VCC1 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) from Mus musculus (see paper)
30% identity, 96% coverage of query (96.3 bits)
A0A0G2SJM3 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Fimbriaphyllia ancora (see paper)
31% identity, 76% coverage of query (96.3 bits)
6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
29% identity, 95% coverage of query (96.3 bits)
6t62A / V5VHN7 Crystal structure of acinetobacter baumannii fabg in complex with NADPH at 1.8 a resolution (see paper)
29% identity, 99% coverage of query (96.3 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
32% identity, 99% coverage of query (96.3 bits)
6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
29% identity, 95% coverage of query (96.3 bits)
phaB acetoacetyl-CoA reductase PhaB; EC 1.1.1.36 from Acinetobacter sp. RA3849 (see paper)
32% identity, 98% coverage of query (95.9 bits)
RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_RUMGV / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
31% identity, 98% coverage of query (95.9 bits)
6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
29% identity, 95% coverage of query (95.9 bits)
DHB8_MOUSE / P50171 (3R)-3-hydroxyacyl-CoA dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 8; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit; KAR alpha subunit; 3-oxoacyl-[acyl-carrier-protein] reductase; Estradiol 17-beta-dehydrogenase 8; Protein Ke6; Ke-6; Testosterone 17-beta-dehydrogenase 8; EC 1.1.1.n12; EC 1.1.1.62; EC 1.1.1.239 from Mus musculus (Mouse) (see 2 papers)
33% identity, 99% coverage of query (95.5 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
30% identity, 99% coverage of query (95.5 bits)
ABA4_BOTFB / A0A384JQF5 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
32% identity, 96% coverage of query (95.1 bits)
4is3C / P19337 Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (baia2) associated with secondary bile acid synthesis from clostridium scindens vpi12708 in complex with a putative NAD(+)-oh- adduct at 2.0 a resolution
30% identity, 98% coverage of query (95.1 bits)
baiA2 / P19337 3α-hydroxysteroid dehydrogenase 2 (EC 1.1.1.395) from Clostridium scindens (strain JCM 10418 / VPI 12708) (see 4 papers)
BAIA2_CLOSV / P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2; 3alpha-hydroxysteroid dehydrogenase 2; 3alpha-HSDH 2; Bile acid-inducible protein BaiA2; EC 1.1.1.395 from Clostridium scindens (strain JCM 10418 / VPI 12708) (see paper)
P19337 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase (EC 1.1.1.395) from [Clostridium] scindens (see paper)
30% identity, 98% coverage of query (94.7 bits)
5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
37% identity, 94% coverage of query (94.7 bits)
3ndrA / Q988B7 Crystal structure of tetrameric pyridoxal 4-dehydrogenase from mesorhizobium loti
28% identity, 95% coverage of query (94.7 bits)
pldh-t / Q988B7 pyridoxal 4-dehydrogenase subunit (EC 1.1.1.107) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 2 papers)
PLDH_RHILO / Q988B7 Pyridoxal 4-dehydrogenase; tPLDH; EC 1.1.1.107 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see paper)
Q988B7 pyridoxal 4-dehydrogenase (EC 1.1.1.107) from Mesorhizobium loti (see paper)
28% identity, 95% coverage of query (94.7 bits)
BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
31% identity, 96% coverage of query (94.7 bits)
6wprA Crystal structure of a putative 3-oxoacyl-acp reductase (fabg) with NADP(h) from acinetobacter baumannii
29% identity, 99% coverage of query (94.7 bits)
3rwbA Crystal structure of complex of 4pal (4-pyridoxolactone) and pldh (tetrameric pyridoxal 4-dehydrogenase) from mesorhizobium loti
28% identity, 95% coverage of query (94.7 bits)
C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
32% identity, 96% coverage of query (94.4 bits)
6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
32% identity, 95% coverage of query (94.4 bits)
2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
34% identity, 96% coverage of query (94.0 bits)
OsMAS / Q7FAE1 momilactone A synthase (EC 1.1.1.295) from Oryza sativa subsp. japonica (see 2 papers)
MOMAS_ORYSJ / Q7FAE1 Momilactone A synthase; OsMAS; EC 1.1.1.295 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q7FAE1 momilactone-A synthase (EC 1.1.1.295) from Oryza sativa (see 2 papers)
35% identity, 96% coverage of query (93.2 bits)
Q309F3 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) from Bos taurus (see paper)
31% identity, 96% coverage of query (92.8 bits)
E2QX67 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) from Canis lupus familiaris (see paper)
29% identity, 96% coverage of query (92.4 bits)
ABA4_BOTFU / Q14RS1 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
31% identity, 96% coverage of query (92.4 bits)
2hsdA The refined three-dimensional structure of 3alpha,20beta- hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases
36% identity, 95% coverage of query (91.7 bits)
1hdcA / P19992 Mechanism of inhibition of 3alpha,20beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor (see paper)
36% identity, 95% coverage of query (91.7 bits)
novJ / Q9L9F8 NovJ from Streptomyces niveus (see paper)
NOVJ_STRNV / Q9L9F8 Short-chain reductase protein NovJ; Novobiocin biosynthesis protein J; EC 1.1.1.- from Streptomyces niveus (Streptomyces spheroides) (see paper)
33% identity, 96% coverage of query (91.7 bits)
7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
29% identity, 96% coverage of query (90.9 bits)
BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
31% identity, 97% coverage of query (90.5 bits)
4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
32% identity, 96% coverage of query (90.1 bits)
8jfgA / G2M827 Crystal structure of 3-oxoacyl-acp reductase fabg in complex with NADP+ and 3-keto-octanoyl-acp from helicobacter pylori (see paper)
31% identity, 96% coverage of query (89.7 bits)
4ag3A Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with NADPH at 1.8a resolution
30% identity, 99% coverage of query (89.7 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
30% identity, 96% coverage of query (89.4 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
30% identity, 96% coverage of query (89.4 bits)
5iz4A / Q13GL4 Crystal structure of a putative short-chain dehydrogenase/reductase from burkholderia xenovorans
31% identity, 96% coverage of query (89.0 bits)
1nfqA Rv2002 gene product from mycobacterium tuberculosis
32% identity, 95% coverage of query (88.6 bits)
1nffA / P9WGT1 Crystal structure of rv2002 gene product from mycobacterium tuberculosis (see paper)
32% identity, 95% coverage of query (88.6 bits)
7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
30% identity, 96% coverage of query (88.6 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
29% identity, 96% coverage of query (87.8 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
30% identity, 99% coverage of query (87.8 bits)
HSD_MYCTU / P9WGT1 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; NADH-dependent 3alpha, 20beta-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
GI|3261591 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; EC 1.1.1.53 from Mycobacterium tuberculosis H37Rv (see paper)
33% identity, 95% coverage of query (87.8 bits)
RADH_LENKE / Q6WVP7 NADP-dependent (R)-specific alcohol dehydrogenase; (R)-specific ADH; Ketoreductase; KRED; EC 1.1.1.- from Lentilactobacillus kefiri (Lactobacillus kefiri)
30% identity, 96% coverage of query (87.8 bits)
3i3oA 2.06 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD-acetone
28% identity, 95% coverage of query (86.3 bits)
3ijrF / A0A6L8PL20 2.05 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD+
28% identity, 95% coverage of query (86.3 bits)
4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
33% identity, 97% coverage of query (85.9 bits)
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Lawrence Berkeley National Laboratory