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Searching for up to 100 curated homologs for HSERO_RS04820 FitnessBrowser__HerbieS:HSERO_RS04820 (501 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.47.3.4 / Q6D017 The pmf-dependent citrate uptake system, Cit1 from Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) (see paper)
    43% identity, 92% coverage of query (365 bits)

DIT1_SPIOL / Q41364 Dicarboxylate transporter 1, chloroplastic; SODIT1; 2-oxoglutarate/malate translocator from Spinacia oleracea (Spinach) (see 2 papers)
TC 2.A.47.3.1 / Q41364 2-oxoglutarate:malate antiporter (SodiTl) from Spinacia oleracea (Spinach) (see paper)
SODIT1 2-oxoglutarate/malate translocator from Spinacia oleracea (see paper)
SODiT1 / AAA68148.1 2-oxoglutarate/malate translocator from Spinacia oleracea (see paper)
    40% identity, 96% coverage of query (356 bits)

DIT1_ARATH / Q9LXV3 Dicarboxylate transporter 1, chloroplastic; 2-oxoglutarate/malate translocator 1; AtpOMT1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    40% identity, 96% coverage of query (355 bits)

DIT21_ARATH / Q9FMF7 Dicarboxylate transporter 2.1, chloroplastic; AtpDCT1; Glutamate/malate translocator from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    37% identity, 96% coverage of query (315 bits)

DIT2_SPIOL / Q8L7Z9 Dicarboxylate transporter 2, chloroplastic; Glutamate/malate translocator from Spinacia oleracea (Spinach) (see paper)
    38% identity, 96% coverage of query (301 bits)

DIT22_ARATH / Q9FMF8 Dicarboxylate transporter 2.2, chloroplastic; AtpDCT2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    36% identity, 96% coverage of query (293 bits)

YgjC / b3063 L-tartrate:succinate antiporter from Escherichia coli K-12 substr. MG1655
ttdT / P39414 L-tartrate:succinate antiporter from Escherichia coli (strain K12) (see 5 papers)
TTDT_ECOLI / P39414 L-tartrate/succinate antiporter; Tartrate carrier; Tartrate transporter from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.47.3.3 / P39414 L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) from Escherichia coli (see 8 papers)
ttdT / RF|NP_417535 L-tartrate/succinate antiporter from Escherichia coli K12 (see 8 papers)
    37% identity, 93% coverage of query (282 bits)

YbhI / b0770 putative tricarboxylate transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    36% identity, 93% coverage of query (269 bits)

YbdS / b0612 citrate:succinate antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
citT / P0AE74 citrate:succinate antiporter from Escherichia coli (strain K12) (see 3 papers)
CITT_ECOLI / P0AE74 Citrate/succinate antiporter; Citrate carrier; Citrate transporter from Escherichia coli (strain K12) (see paper)
TC 2.A.47.3.2 / P0AE74 Citrate:succinate antiporter from Escherichia coli (see 4 papers)
    33% identity, 97% coverage of query (259 bits)

Build an alignment

Build an alignment for HSERO_RS04820 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

TC 2.A.47.1.12 / A4QAL6 The aerobic dicarboxylate (succinate (Km, 30 μM), fumarate (Km, 79 from Corynebacterium glutamicum (strain R) (see paper)
    24% identity, 86% coverage of query (68.9 bits)

SDCS_STAAM / Q99SX1 Sodium-dependent dicarboxylate transporter SdcS; Na(+)/dicarboxylate symporter from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see 2 papers)
    25% identity, 83% coverage of query (66.6 bits)

TC 2.A.47.1.11 / Q2FFH9 The Na+ (or Li+):dicarboxylate (2:1) symporter, SdcS (catalyzes succinate:succinate antiport as well as electroneutral symport in reconstituted proteoliposomes from Staphylococcus aureus (strain USA300) (see paper)
    24% identity, 83% coverage of query (64.3 bits)

TC 2.A.47.1.13 / Q65NC0 The Na+-coupled dicarboxylate (succinate; malate; fumarate) transporter, SdcL (transports aspartate, α-ketoglutarate and oxaloacetate with low affinity). Km for succinate, ~6 from Bacillus licheniformis (strain DSM 13 / ATCC 14580) (see 2 papers)
    23% identity, 90% coverage of query (55.5 bits)

7t9gA / Q9KNE0 Structure of vcindy-na+ (see paper)
    24% identity, 80% coverage of query (48.9 bits)

6okzB Structure of vcindy bound to fumarate
    24% identity, 80% coverage of query (48.9 bits)

6wtxA Structure of vcindy in complex with terephthalate
    24% identity, 80% coverage of query (48.9 bits)

VCA0025 / Q9KNE0 dicarboxylate:Na+ symporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 6 papers)
TC 2.A.47.5.2 / Q9KNE0 Dicarboxylate (succinate, fumarate, malate) transporter, vcINDY from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    24% identity, 80% coverage of query (48.5 bits)

NAD3_CAEEL / Q21339 Sodium-dependent high-affinity dicarboxylate transporter 3; Na(+)/dicarboxylate cotransporter 3; NaDC-3; ceNaDC3 from Caenorhabditis elegans (see paper)
TC 2.A.47.1.8 / Q21339 High affinity dicarboxylate:Na+ symporter, NaDC2 (INDY2) (relative affinities: fumarate > malate > α-ketoglutarate > maleate > succinate > lactate) (see 2 papers)
    21% identity, 86% coverage of query (48.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory