Sites on a Tree

 

Searching for up to 100 curated homologs for HSERO_RS05155 FitnessBrowser__HerbieS:HSERO_RS05155 (212 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DGOA_RHIME / Q92RN8 Probable 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    51% identity, 92% coverage of query (168 bits)

YidU / b4477 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55; EC 4.1.2.21) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dgoA / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55) from Escherichia coli (strain K12) (see 5 papers)
DGOA_ECOLI / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Escherichia coli (strain K12) (see 3 papers)
Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.21) from Escherichia coli (see paper)
dgoA / RF|YP_026238 2-dehydro-3-deoxy-6-phosphogalactonate aldolase from Escherichia coli K12 (see 2 papers)
    48% identity, 91% coverage of query (164 bits)

2v82A / Q6BF16 Kdpgal complexed to kdpgal (see paper)
    48% identity, 91% coverage of query (164 bits)

lgnG / BAM68210.1 2-keto-3-deoxy-6-phosphogalactonate aldolase lgnG from Paracoccus laeviglucosivorans (see 2 papers)
    45% identity, 91% coverage of query (153 bits)

1wa3D / Q9WXS1 Mechanism of the class i kdpg aldolase (see paper)
    32% identity, 94% coverage of query (110 bits)

TM0066 / Q9WXS1 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16; EC 4.1.2.55) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    32% identity, 94% coverage of query (110 bits)

D4GV57 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Haloferax volcanii (see paper)
    33% identity, 73% coverage of query (81.3 bits)

Build an alignment

Build an alignment for HSERO_RS05155 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

CA265_RS19860 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Pedobacter sp. GW460-11-11-14-LB5
    27% identity, 88% coverage of query (73.9 bits)

ALKD_PSEA6 / Q15X88 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phospho-D-gluconate aldolase; KDPG aldolase; EC 4.1.2.14 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
    33% identity, 71% coverage of query (70.5 bits)

ALKH_BACSU / P50846 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Bacillus subtilis (strain 168) (see paper)
    29% identity, 84% coverage of query (68.2 bits)

A0A0B6VQ18 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Flavobacterium sp. UMI-01 (see paper)
    26% identity, 84% coverage of query (55.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory