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Searching for up to 100 curated homologs for HSERO_RS05190 FitnessBrowser__HerbieS:HSERO_RS05190 (357 a.a.)

Found high-coverage hits (≥70%) to 33 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

chvE / CAC67776.1 sugar-binding protein from Brucella suis (see paper)
    76% identity, 98% coverage of query (554 bits)

TC 3.A.1.2.5 / P25548 CVE1 aka ChvE aka ATU2348 aka AGR_C_4267, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium tumefaciens (see 4 papers)
    77% identity, 99% coverage of query (550 bits)

3urmA / P25548 Crystal structure of the periplasmic sugar binding protein chve (see paper)
    82% identity, 91% coverage of query (547 bits)

3uugA Crystal structure of the periplasmic sugar binding protein chve
    82% identity, 91% coverage of query (547 bits)

SBPA_AZOBR / P54083 Multiple sugar-binding periplasmic protein SbpA; Sugar-binding protein A from Azospirillum brasilense (see paper)
    75% identity, 99% coverage of query (537 bits)

4wwhA / A0QT42 Crystal structure of an abc transporter solute binding protein (ipr025997) from mycobacterium smegmatis (msmeg_1704, target efi- 510967) with bound d-galactose
    65% identity, 92% coverage of query (447 bits)

4ys6A / A9KQP6 Crystal structure of an abc transporter solute binding protein (ipr025997) from clostridium phytofermentans (cphy_1585, target efi- 511156) with bound beta-d-glucose
    52% identity, 92% coverage of query (342 bits)

TC 3.A.1.2.22 / Q8G3R1 Probable sugar binding protein of ABC transporter for pentoses, component of ABC sugar transporter that plays a role in the probiotic benefits through acetate production from Bifidobacterium longum (strain NCC 2705)
    39% identity, 99% coverage of query (236 bits)

XylT / b3566 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
xylF / P37387 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13) from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.2.4 / P37387 XylF aka XYLT aka B3566, component of Xylose porter from Escherichia coli (see 5 papers)
xylF / GB|AAC76590.1 D-xylose ABC transporter, periplasmic D-xylose-binding protein from Escherichia coli K12 (see 7 papers)
    37% identity, 93% coverage of query (180 bits)

4rxuA / A9WDY0 Crystal structure of carbohydrate transporter solute binding protein caur_1924 from chloroflexus aurantiacus, target efi-511158, in complex with d-glucose
    36% identity, 91% coverage of query (179 bits)

3ma0A / P37387 Closed liganded crystal structure of xylose binding protein from escherichia coli (see paper)
    37% identity, 91% coverage of query (177 bits)

4ywhA / A6VLM7 Crystal structure of an abc transporter solute binding protein (ipr025997) from actinobacillus succinogenes 130z (asuc_0499, target efi-511068) with bound d-xylose
    36% identity, 90% coverage of query (167 bits)

TC 3.A.1.2.26 / A6LW10 D-xylose ABC transporter, periplasmic substrate-binding protein, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
    33% identity, 98% coverage of query (161 bits)

TC 3.A.1.2.24 / O50503 Solute-binding protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    33% identity, 90% coverage of query (137 bits)

Build an alignment

Build an alignment for HSERO_RS05190 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PGA1_262p00430 glucose transporter, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    29% identity, 96% coverage of query (123 bits)

6s3tA / P0C0J8 P46, an immunodominant surface protein from mycoplasma hyopneumoniae (see paper)
    29% identity, 87% coverage of query (115 bits)

6ruxA P46, an immunodominant surface protein from mycoplasma hyopneumoniae
    29% identity, 87% coverage of query (115 bits)

4z0nA / D1AWX5 Crystal structure of a periplasmic solute binding protein (ipr025997) from streptobacillus moniliformis dsm-12112 (smon_0317, target efi- 511281) with bound d-galactose
    26% identity, 82% coverage of query (68.9 bits)

MglB / b2150 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 43 papers)
MglB / P0AEE5 D-galactose/methyl-galactoside ABC transporter periplasmic binding protein from Escherichia coli (strain K12) (see 42 papers)
MGLB_ECOLI / P0AEE5 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.3 / P0AEE5 D-galactose-binding periplasmic protein DGAL aka MglB aka B2150, component of Galactose/glucose (methyl galactoside) porter from Escherichia coli (see 10 papers)
    26% identity, 77% coverage of query (60.1 bits)

2gbpA / P0AEE5 Sugar and signal-transducer binding sites of the escherichia coli galactose chemoreceptor protein (see paper)
    26% identity, 77% coverage of query (59.7 bits)

P23905 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    26% identity, 77% coverage of query (59.3 bits)

2qw1A Glucose/galactose binding protein bound to 3-o-methyl d-glucose
    26% identity, 77% coverage of query (59.3 bits)

3ga5A X-ray structure of glucose/galactose receptor from salmonella typhimurium in complex with (2r)-glyceryl-beta-d-galactopyranoside
    26% identity, 77% coverage of query (58.9 bits)

1gcaA The 1.7 angstroms refined x-ray structure of the periplasmic glucose(slash)galactose receptor from salmonella typhimurium
    26% identity, 77% coverage of query (58.5 bits)

5kwsA / Q8D072 Crystal structure of galactose binding protein from yersinia pestis in the complex with beta d glucose
    25% identity, 77% coverage of query (56.2 bits)

8fxtA Escherichia coli periplasmic glucose-binding protein glucose complex: acrylodan conjugate attached at w183c
    26% identity, 77% coverage of query (54.7 bits)

TC 3.A.1.2.16 / Q1M4Q9 Periplasmic erythritol binding protein, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    24% identity, 84% coverage of query (53.5 bits)

5dteB / A6VKG5 Crystal structure of an abc transporter periplasmic solute binding protein (ipr025997) from actinobacillus succinogenes 130z(asuc_0081, target efi-511065) with bound d-allose
    25% identity, 72% coverage of query (51.2 bits)

PS417_12055 xylitol ABC transporter, substrate-binding component from Pseudomonas simiae WCS417
    24% identity, 76% coverage of query (48.1 bits)

4ry9A / A1WJM2 Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    22% identity, 86% coverage of query (47.0 bits)

4ry9B Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    22% identity, 86% coverage of query (47.0 bits)

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    23% identity, 71% coverage of query (46.6 bits)

4zjpA / A6VKT0 Structure of an abc-transporter solute binding protein (sbp_ipr025997) from actinobacillus succinogenes (asuc_0197, target efi-511067) with bound beta-d-ribopyranose
    22% identity, 71% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory