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Searching for up to 100 curated homologs for HSERO_RS05315 FitnessBrowser__HerbieS:HSERO_RS05315 (302 a.a.)

Found high-coverage hits (≥70%) to 71 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2ioyA / Q8RD41 Crystal structure of thermoanaerobacter tengcongensis ribose binding protein (see paper)
    37% identity, 89% coverage of query (172 bits)

RBSB_BACSU / P36949 Ribose import binding protein RbsB from Bacillus subtilis (strain 168) (see 2 papers)
    37% identity, 86% coverage of query (163 bits)

RbsB / b3751 ribose ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 25 papers)
RbsB / P02925 ribose ABC transporter periplasmic binding protein from Escherichia coli (strain K12) (see 25 papers)
RBSB_ECOLI / P02925 Ribose import binding protein RbsB from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.2.1 / P02925 RbsB aka RBSP aka PRLB aka B3751, component of Ribose porter from Escherichia coli (see 11 papers)
rbsB / GB|AAC76774.1 D-ribose-binding periplasmic protein; EC 3.6.3.17 from Escherichia coli K12 (see 11 papers)
    34% identity, 96% coverage of query (134 bits)

5dteB / A6VKG5 Crystal structure of an abc transporter periplasmic solute binding protein (ipr025997) from actinobacillus succinogenes 130z(asuc_0081, target efi-511065) with bound d-allose
    32% identity, 85% coverage of query (130 bits)

1dbpA / P02925 Identical mutations at corresponding positions in two homologous proteins with non-identical effects (see paper)
    34% identity, 89% coverage of query (130 bits)

7e7mC / Q8E283 Crystal structure analysis of the streptococcus agalactiae ribose binding protein rbsb
    32% identity, 92% coverage of query (127 bits)

TC 3.A.1.2.19 / Q9X053 Periplasmic binding protein/LacI transcriptional regulator, component of D-ribose porter (Nanavati et al., 2006). Induced by ribose from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    30% identity, 92% coverage of query (126 bits)

TC 3.A.1.2.13 / A6VKT0 RbsB, component of The probable autoinducer-2 (AI-2;, a furanosyl borate diester: 3aS,6S,6aR)-2,2,6,6a-tetrahydroxy-3a-methyltetrahydrofuro[3,2-d][1,3,2]dioxaborolan-2-uide) uptake porter (Shao et al., 2007) (50-70% identical to RbsABC of E. coli; TC# 3.A.1.2.1) from Actinobacillus succinogenes (strain ATCC 55618 / 130Z)
    32% identity, 94% coverage of query (126 bits)

2fn8A / Q9X053 Thermotoga maritima ribose binding protein ribose bound form (see paper)
    30% identity, 90% coverage of query (124 bits)

4zjpA / A6VKT0 Structure of an abc-transporter solute binding protein (sbp_ipr025997) from actinobacillus succinogenes (asuc_0197, target efi-511067) with bound beta-d-ribopyranose
    32% identity, 88% coverage of query (122 bits)

HSERO_RS03635 D-mannose ABC transporter, substrate-binding component from Herbaspirillum seropedicae SmR1
    32% identity, 91% coverage of query (119 bits)

AlsB / b4088 D-allose ABC transporter periplasmic binding protein (EC 7.5.2.8) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
AlsB / P39265 D-allose ABC transporter periplasmic binding protein (EC 7.5.2.8) from Escherichia coli (strain K12) (see 5 papers)
ALSB_ECOLI / P39265 D-allose-binding periplasmic protein; ALBP from Escherichia coli (strain K12) (see paper)
P39265 ABC-type D-allose transporter (EC 7.5.2.8) from Escherichia coli (see paper)
TC 3.A.1.2.6 / P39265 AlsB aka B4088, component of D-allose porter from Escherichia coli (see 6 papers)
alsB / GB|AAC77049.1 D-allose-binding periplasmic protein; EC 3.6.3.17 from Escherichia coli K12 (see 6 papers)
    31% identity, 92% coverage of query (107 bits)

1gudA / P39265 Hinge-bending motion of d-allose binding protein from escherichia coli: three open conformations (see paper)
    31% identity, 83% coverage of query (105 bits)

Build an alignment

Build an alignment for HSERO_RS05315 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

PS417_11885 Inositol transport system sugar-binding protein from Pseudomonas simiae WCS417
    29% identity, 81% coverage of query (105 bits)

1rpjA Crystal structure of d-allose binding protein from escherichia coli
    31% identity, 83% coverage of query (105 bits)

4irxA / A0A0H3C834 Crystal structure of caulobacter myo-inositol binding protein bound to myo-inositol (see paper)
    32% identity, 84% coverage of query (102 bits)

THPA_MYCS2 / A0QYB5 D-threitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    30% identity, 96% coverage of query (100 bits)

XYPA_MYCS2 / A0QYB3 Xylitol-binding protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    29% identity, 89% coverage of query (100 bits)

4rs3A / A0QYB3 Crystal structure of carbohydrate transporter a0qyb3 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with xylitol (see paper)
    29% identity, 89% coverage of query (100 bits)

5hqjA / B1G1H7 Crystal structure of abc transporter solute binding protein b1g1h7 from burkholderia graminis c4d1m, target efi-511179, in complex with d-arabinose
    28% identity, 87% coverage of query (100 bits)

PS417_12055 xylitol ABC transporter, substrate-binding component from Pseudomonas simiae WCS417
    30% identity, 75% coverage of query (100 bits)

TC 3.A.1.2.21 / B8H228 Inositol ABC transporter, periplasmic inositol-binding protein IbpA, component of The myoinositol (high affinity)/ D-ribose (low affinity) transporter IatP/IatA/IbpA. The structure of IbpA with myoinositol bound has been solved from Caulobacter crescentus (strain NA1000 / CB15N)
    33% identity, 82% coverage of query (100 bits)

5hkoA Crystal structure of abc transporter solute binding protein msmeg_3598 from mycobacterium smegmatis str. Mc2 155, target efi-510969, in complex with l-sorbitol
    29% identity, 89% coverage of query (100 bits)

4rsmA / A0QYB5 Crystal structure of carbohydrate transporter msmeg_3599 from mycobacterium smegmatis str. Mc2 155, target efi-510970, in complex with d-threitol (see paper)
    30% identity, 89% coverage of query (98.6 bits)

8wlbA X-ray structure of enterobacter cloacae allose-binding protein in complex with d-psicose
    30% identity, 87% coverage of query (97.8 bits)

8wl9A X-ray structure of enterobacter cloacae allose-binding protein in complex with d-ribose
    30% identity, 87% coverage of query (97.8 bits)

RR42_RS03370 fructose ABC transporter, substrate-binding component (FrcB) from Cupriavidus basilensis FW507-4G11
    34% identity, 71% coverage of query (97.4 bits)

4yo7A / Q9KAG4 Crystal structure of an abc transporter solute binding protein (ipr025997) from bacillus halodurans c-125 (bh2323, target efi- 511484) with bound myo-inositol
    27% identity, 74% coverage of query (88.6 bits)

4ry9A / A1WJM2 Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    29% identity, 74% coverage of query (86.7 bits)

4ry9B Crystal structure of carbohydrate transporter solute binding protein veis_2079 from verminephrobacter eiseniae ef01-2, target efi-511009, a complex with d-talitol
    29% identity, 74% coverage of query (86.7 bits)

Shewana3_2073 L-arabinose ABC transporter, substrate-binding component AraU from Shewanella sp. ANA-3
    29% identity, 82% coverage of query (85.9 bits)

6hbdA / A0QT50 Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with beta-d-galactofuranose (see paper)
    26% identity, 74% coverage of query (82.8 bits)

6hyhA Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with beta-d-fucofuranose
    26% identity, 74% coverage of query (82.8 bits)

6hbmA Crystal structure of msmeg_1712 from mycobacterium smegmatis in complex with alpha-l-arabinofuranose
    26% identity, 74% coverage of query (82.8 bits)

2rjoA / B2TEP5 Crystal structure of twin-arginine translocation pathway signal protein from burkholderia phytofirmans
    27% identity, 84% coverage of query (82.0 bits)

5ocpA / A0KWY4 The periplasmic binding protein component of the arabinose abc transporter from shewanella sp. Ana-3 bound to alpha and beta-l- arabinofuranose
    29% identity, 74% coverage of query (81.3 bits)

TC 3.A.1.2.16 / Q1M4Q9 Periplasmic erythritol binding protein, component of The erythritol uptake permease, EryEFG (Yost et al., 2006) (probably orthologous to 3.A.1.2.11) from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    31% identity, 71% coverage of query (80.5 bits)

HSERO_RS11480 D-ribose ABC transporter, substrate-binding component RbsB from Herbaspirillum seropedicae SmR1
    29% identity, 89% coverage of query (80.1 bits)

4rxmA Crystal structure of periplasmic abc transporter solute binding protein a7jw62 from mannheimia haemolytica phl213, target efi-511105, in complex with myo-inositol
    28% identity, 79% coverage of query (78.2 bits)

4rxmB Crystal structure of periplasmic abc transporter solute binding protein a7jw62 from mannheimia haemolytica phl213, target efi-511105, in complex with myo-inositol
    28% identity, 79% coverage of query (77.8 bits)

2x7xA / Q8A6X1 Fructose binding periplasmic domain of hybrid two component system bt1754 (see paper)
    25% identity, 83% coverage of query (73.6 bits)

2h3hA / Q9WXW9 Crystal structure of the liganded form of thermotoga maritima glucose binding protein (see paper)
    24% identity, 71% coverage of query (72.8 bits)

RALBP_PSEAE / Q9I2F8 D-ribose/D-allose-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    26% identity, 90% coverage of query (72.0 bits)

APIBP_AGRRK / B9JK76 D-apiose import binding protein; D-apiose binding SBP from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
    28% identity, 80% coverage of query (70.9 bits)

3c6qC Apo and ligand-bound form of a thermophilic glucose/xylose binding protein
    24% identity, 71% coverage of query (70.9 bits)

eryG / Q2YIY2 putative erythritol ABC transporter substrate-binding protein from Brucella abortus (strain 2308) (see 3 papers)
    26% identity, 71% coverage of query (70.5 bits)

FRCB_RHIML / Q9F9B2 Fructose import binding protein FrcB from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 3.A.1.2.7 / Q9F9B2 FrcB, component of Fructose/mannose/ribose porter from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    27% identity, 86% coverage of query (68.2 bits)

Pf1N1B4_6035 D-ribose ABC transporter, substrate-binding component RbsB from Pseudomonas fluorescens FW300-N1B4
    25% identity, 84% coverage of query (67.4 bits)

TC 3.A.1.2.24 / O50503 Solute-binding protein, component of XylFGH downstream of characterized transcriptional regulator, ROK7B7 (Sco6008); XylF (Sco6009); XylG (Sco6010); XylH (Sco6011)) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    25% identity, 80% coverage of query (67.4 bits)

APIBP_ACTSZ / A6VKQ8 D-apiose import binding protein; D-apiose binding SBP from Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) (see paper)
    25% identity, 76% coverage of query (66.2 bits)

APIBP_PARG4 / B1G898 D-apiose import binding protein; D-apiose binding SBP from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
    27% identity, 81% coverage of query (65.5 bits)

APIBP_RHIEC / Q2JZQ5 D-apiose import binding protein; D-apiose binding SBP from Rhizobium etli (strain CFN 42 / ATCC 51251) (see paper)
    26% identity, 71% coverage of query (65.1 bits)

5ibqA / Q2JZQ5 Crystal structure of an abc solute binding protein from rhizobium etli cfn 42 (rhe_pf00037,target efi-511357) in complex with alpha-d-apiose
    26% identity, 71% coverage of query (64.3 bits)

XylT / b3566 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
xylF / P37387 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13) from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.2.4 / P37387 XylF aka XYLT aka B3566, component of Xylose porter from Escherichia coli (see 5 papers)
xylF / GB|AAC76590.1 D-xylose ABC transporter, periplasmic D-xylose-binding protein from Escherichia coli K12 (see 7 papers)
    29% identity, 76% coverage of query (64.3 bits)

4ry0A Crystal structure of ribose transporter solute binding protein rhe_pf00037 from rhizobium etli cfn 42, target efi-511357, in complex with d-ribose
    26% identity, 71% coverage of query (64.3 bits)

TC 3.A.1.2.11 / Q92WK4 EryG aka RB0335, component of The erythritol permease, EryEFG (Geddes et al., 2010) (probably orthologous to 3.A.1.2.16) from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    26% identity, 71% coverage of query (63.9 bits)

3ma0A / P37387 Closed liganded crystal structure of xylose binding protein from escherichia coli (see paper)
    29% identity, 75% coverage of query (63.9 bits)

4wutA / B9K0B2 Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis (avi_5133, target efi-511220) with bound d-fucose
    24% identity, 89% coverage of query (63.2 bits)

RbsR / VIMSS66308 RbsR regulator of Ribose utilization, effector Ribose (repressor) from Bacillus halodurans C-125
    24% identity, 71% coverage of query (62.8 bits)

PGA1_262p00430 glucose transporter, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    26% identity, 78% coverage of query (62.8 bits)

BPHYT_RS34250 ABC transporter for L-rhamnose/L-fucose/xylitol, substrate-binding component from Burkholderia phytofirmans PsJN
    26% identity, 82% coverage of query (61.6 bits)

HSERO_RS05260 ABC transporter for L-fucose, substrate-binding component from Herbaspirillum seropedicae SmR1
    26% identity, 81% coverage of query (60.5 bits)

TC 3.A.1.2.26 / A6LW10 D-xylose ABC transporter, periplasmic substrate-binding protein, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
    28% identity, 73% coverage of query (59.7 bits)

TC 3.A.1.2.9 / Q7BSH5 RhaS, component of Rhamnose porter (Richardson et al., 2004) (Transport activity is dependent on rhamnokinase (RhaK; AAQ92412) activity (Richardson and Oresnik, 2007) This could be an example of group translocation!) from Rhizobium leguminosarum (biovar trifolii) (see paper)
    28% identity, 73% coverage of query (59.3 bits)

5dkvA / B9K0T2 Crystal structure of an abc transporter solute binding protein from agrobacterium vitis(avis_5339, target efi-511225) bound with alpha-d- tagatopyranose
    26% identity, 76% coverage of query (59.3 bits)

4ywhA / A6VLM7 Crystal structure of an abc transporter solute binding protein (ipr025997) from actinobacillus succinogenes 130z (asuc_0499, target efi-511068) with bound d-xylose
    30% identity, 74% coverage of query (58.9 bits)

6gt9A / W8QN64 Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with galactose
    23% identity, 72% coverage of query (58.5 bits)

6guqA Crystal structure of ganp, a glucose-galactose binding protein from geobacillus stearothermophilus, in complex with glucose
    23% identity, 72% coverage of query (58.5 bits)

4wt7A / B9K0E0 Crystal structure of an abc transporter solute binding protein (ipr025997) from agrobacterium vitis (avi_5165, target efi-511223) with bound allitol
    23% identity, 73% coverage of query (55.8 bits)

7x0hA / A3DCF2 Crystal structure of sugar binding protein cbpa complexed wtih glucose from clostridium thermocellum (see paper)
    22% identity, 85% coverage of query (47.8 bits)

4z0nA / D1AWX5 Crystal structure of a periplasmic solute binding protein (ipr025997) from streptobacillus moniliformis dsm-12112 (smon_0317, target efi- 511281) with bound d-galactose
    24% identity, 82% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory