Searching for up to 100 curated homologs for HSERO_RS05800 FitnessBrowser__HerbieS:HSERO_RS05800 (455 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gudD / P42206 D-glucarate dehydratase subunit (EC 4.2.1.40) from Pseudomonas putida (see paper)
GUDD_PSEPU / P42206 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    79% identity, 98% coverage of query (719 bits)

YgcX / b2787 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gudD / P0AES2 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli (strain K12) (see 5 papers)
GUDD_ECOLI / P0AES2 Glucarate dehydratase; GDH; GlucD; D-glucarate dehydratase; EC 4.2.1.40 from Escherichia coli (strain K12) (see 3 papers)
gudD / RF|NP_417267 glucarate dehydratase; EC 4.2.1.40 from Escherichia coli K12 (see 8 papers)
    74% identity, 96% coverage of query (691 bits)

1ec9D / P0AES2 E. Coli glucarate dehydratase bound to xylarohydroxamate (see paper)
    74% identity, 96% coverage of query (691 bits)

1ecqA E. Coli glucarate dehydratase bound to 4-deoxyglucarate
    74% identity, 96% coverage of query (691 bits)

1ec8A E. Coli glucarate dehydratase bound to product 2,3-dihydroxy-5-oxo- hexanedioate
    74% identity, 96% coverage of query (691 bits)

1jctA Glucarate dehydratase, n341l mutant orthorhombic form
    74% identity, 96% coverage of query (686 bits)

gudD / Q6FFQ2 D-glucarate dehydratase subunit (EC 4.2.1.40) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
GUDD_ACIAD / Q6FFQ2 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ2 glucarate dehydratase (EC 4.2.1.40) from Acinetobacter baylyi (see paper)
    67% identity, 96% coverage of query (637 bits)

3p0wB / B2UIZ1 Crystal structure of d-glucarate dehydratase from ralstonia solanacearum complexed with mg and d-glucarate
    71% identity, 96% coverage of query (597 bits)

3nxlC / Q39KL8 Crystal structure of glucarate dehydratase from burkholderia cepacia complexed with magnesium
    70% identity, 96% coverage of query (575 bits)

GudX / b2788 glucarate dehydratase-related protein from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GUDX_ECOLI / Q46915 Glucarate dehydratase-related protein; GDH-RP; GlucDRP; EC 4.2.1.- from Escherichia coli (strain K12) (see paper)
gudX / RF|NP_417268 glucarate dehydratase-related protein from Escherichia coli K12
    64% identity, 97% coverage of query (567 bits)

3nfuA / Q1QUN0 Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesium
    61% identity, 96% coverage of query (567 bits)

3n6hB / A6VQF6 Crystal structure of mandelate racemase/muconate lactonizing protein from actinobacillus succinogenes 130z complexed with magnesium/sulfate
    60% identity, 97% coverage of query (524 bits)

3pfrA Crystal structure of d-glucarate dehydratase related protein from actinobacillus succinogenes complexed with d-glucarate
    60% identity, 96% coverage of query (521 bits)

3va8A Crystal structure of enolase fg03645.1 (target efi-502278) from gibberella zeae ph-1 complexed with magnesium, formate and sulfate
    34% identity, 95% coverage of query (224 bits)

4it1D / Q3KB33 Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
    35% identity, 94% coverage of query (224 bits)

3vc6A / D6Y7Y6 Crystal structure of enolase tbis_1083(target efi-502310) from thermobispora bispora dsm 43833 complexed with magnesium and formate
    35% identity, 94% coverage of query (213 bits)

Build an alignment

Build an alignment for HSERO_RS05800 and 16 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

D4GYD4 gluconate dehydratase (EC 4.2.1.39) from Haloferax volcanii (see paper)
    25% identity, 82% coverage of query (75.5 bits)

3cb3A / Q12GE3 Crystal structure of l-talarate dehydratase from polaromonas sp. Js666 complexed with mg and l-glucarate
    24% identity, 88% coverage of query (55.8 bits)

2og9A Crystal structure of mandelate racemase/muconate lactonizing enzyme from polaromonas sp. Js666
    24% identity, 82% coverage of query (54.3 bits)

4h1zB / Q92ZS5 Crystal structure of putative isomerase from sinorhizobium meliloti, open loop conformation (target efi-502104)
    25% identity, 81% coverage of query (45.4 bits)

C3HPD_ROSAI / A0NXQ8 Cis-3-hydroxy-L-proline dehydratase; c3LHyp dehydratase; c3LHypD; EC 4.2.1.171 from Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) (see paper)
A0NXQ8 cis-L-3-hydroxyproline dehydratase (EC 4.2.1.171) from Roseibium aggregatum (see paper)
    22% identity, 75% coverage of query (44.7 bits)

4mggA / A0NXQ8 Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121
    22% identity, 75% coverage of query (44.7 bits)

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