Searching for up to 100 curated homologs for HSERO_RS06450 FitnessBrowser__HerbieS:HSERO_RS06450 (305 a.a.)
Found high-coverage hits (≥70%) to 70 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
A9CL97 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
65% identity, 98% coverage of query (390 bits)
dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
30% identity, 94% coverage of query (103 bits)
DAPA_NEIMB / Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Neisseria meningitidis (see paper)
30% identity, 98% coverage of query (103 bits)
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4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
28% identity, 99% coverage of query (102 bits)
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
28% identity, 99% coverage of query (102 bits)
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
28% identity, 99% coverage of query (102 bits)
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
28% identity, 99% coverage of query (102 bits)
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
28% identity, 99% coverage of query (102 bits)
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
28% identity, 99% coverage of query (102 bits)
YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
30% identity, 79% coverage of query (101 bits)
4i7wA / F0L8Z6 Agrobacterium tumefaciens dhdps with lysine and pyruvate
32% identity, 99% coverage of query (97.1 bits)
DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see 2 papers)
32% identity, 99% coverage of query (96.7 bits)
1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
27% identity, 92% coverage of query (95.9 bits)
DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti (see 2 papers)
30% identity, 99% coverage of query (95.9 bits)
DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
27% identity, 92% coverage of query (95.5 bits)
dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
33% identity, 91% coverage of query (95.1 bits)
dapA2 dihydrodipicolinate synthase; EC 4.2.1.52 from Bacillus anthracis (see paper)
29% identity, 98% coverage of query (92.8 bits)
Q8A3Z0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacteroides thetaiotaomicron (see paper)
28% identity, 99% coverage of query (85.9 bits)
dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
26% identity, 98% coverage of query (85.5 bits)
7lvlA / A0A0F4VK59 Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
27% identity, 91% coverage of query (82.8 bits)
7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
27% identity, 91% coverage of query (82.8 bits)
8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
27% identity, 100% coverage of query (82.0 bits)
O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus (see paper)
26% identity, 97% coverage of query (81.3 bits)
4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
27% identity, 93% coverage of query (80.9 bits)
Q6G468 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bartonella henselae (see paper)
27% identity, 99% coverage of query (79.7 bits)
DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
28% identity, 82% coverage of query (77.4 bits)
YagE / b0268 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yagE / P75682 CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase (EC 4.1.2.28; EC 4.1.2.51) from Escherichia coli (strain K12) (see 8 papers)
YAGE_ECOLI / P75682 Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE; KDG aldolase YagE; Putative 2-dehydro-3-deoxy-D-pentonate aldolase YagE; EC 4.1.2.51; EC 4.1.2.28 from Escherichia coli (strain K12) (see 4 papers)
P75682 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20) from Escherichia coli (see paper)
25% identity, 93% coverage of query (77.0 bits)
3nevA / P75682 Crystal structure of yage, a prophage protein from e. Coli k12 in complex with kdgal (see paper)
25% identity, 93% coverage of query (77.0 bits)
4ptnA Crystal structure of yage, a kdg aldolase protein in complex with magnesium cation coordinated l-glyceraldehyde
25% identity, 93% coverage of query (77.0 bits)
4onvA Crystal structure of yage, a kdg aldolase protein in complex with 2- keto-3-deoxy gluconate
25% identity, 93% coverage of query (77.0 bits)
4oe7D Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
25% identity, 93% coverage of query (77.0 bits)
4oe7B Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
25% identity, 93% coverage of query (77.0 bits)
4oe7A Crystal structure of yage, a kdg aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
25% identity, 93% coverage of query (77.0 bits)
DAPA_PSEAE / Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I4W3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Pseudomonas aeruginosa (see 2 papers)
27% identity, 97% coverage of query (76.6 bits)
A5F699 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Vibrio cholerae (see paper)
25% identity, 98% coverage of query (75.1 bits)
5ktlA / Q3M723 Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
26% identity, 98% coverage of query (72.0 bits)
Q3M723 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Trichormus variabilis (see paper)
26% identity, 98% coverage of query (72.0 bits)
3puoA / Q9I4W3 Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
27% identity, 97% coverage of query (72.0 bits)
3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
27% identity, 97% coverage of query (72.0 bits)
5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
25% identity, 98% coverage of query (71.6 bits)
5c55A / Q8NMD2 Crystal structure of the y138f mutant of c.Glutamicum n- acetylneuraminic acid lyase in complex with pyruvate
27% identity, 91% coverage of query (71.6 bits)
DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
25% identity, 98% coverage of query (71.6 bits)
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
25% identity, 98% coverage of query (71.6 bits)
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
26% identity, 94% coverage of query (70.9 bits)
Q8NMD2 N-acetylneuraminate lyase (EC 4.1.3.3) from Corynebacterium glutamicum (see paper)
27% identity, 92% coverage of query (70.5 bits)
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
24% identity, 98% coverage of query (70.5 bits)
3na8A / Q9I6R5 Crystal structure of a putative dihydrodipicolinate synthetase from pseudomonas aeruginosa
26% identity, 83% coverage of query (64.3 bits)
HOGA1 / Q86XE5 4-hydroxy-2-ketoglutarate aldolase subunit (EC 4.1.3.16) from Homo sapiens (see 6 papers)
HOGA1_HUMAN / Q86XE5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; Protein 569272; EC 4.1.3.16 from Homo sapiens (Human) (see 2 papers)
Q86XE5 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) from Homo sapiens (see 5 papers)
25% identity, 77% coverage of query (63.9 bits)
6rb7A / A7B555 Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant (see paper)
26% identity, 98% coverage of query (60.1 bits)
6rd1A Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant in complex with sialic acid
26% identity, 98% coverage of query (60.1 bits)
HOGA1_BOVIN / Q0P5I5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Bos taurus (Bovine) (see 2 papers)
Q0P5I5 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) from Bos taurus (see paper)
25% identity, 95% coverage of query (58.2 bits)
NANA_LACPL / P59407 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
25% identity, 77% coverage of query (57.8 bits)
Ac3H11_603 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Acidovorax sp. GW101-3H11
22% identity, 90% coverage of query (57.8 bits)
C8P490 N-acetylneuraminate lyase (EC 4.1.3.3) from Limosilactobacillus antri (see paper)
26% identity, 96% coverage of query (57.8 bits)
A9CHR2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
24% identity, 93% coverage of query (57.0 bits)
Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
25% identity, 82% coverage of query (57.0 bits)
7mdsA Crystal structure of atdhdps1 in complex with mbdta-2
25% identity, 97% coverage of query (55.5 bits)
6vvhBBB / Q9LZX6 thaliana dihydrodipicolinate synthase isoform 1 (dhdps1) in complex with lysine (see paper)
25% identity, 97% coverage of query (55.1 bits)
A9CGZ4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
25% identity, 90% coverage of query (52.4 bits)
2hmcA / A9CGZ4 The crystal structure of dihydrodipicolinate synthase dapa from agrobacterium tumefaciens
25% identity, 90% coverage of query (51.6 bits)
CH_124068 putative dihydrodipicolinate synthase from Magnaporthe grisea 70-15 (see paper)
24% identity, 77% coverage of query (50.1 bits)
HOGA1_EMENI / Q5BD77 Probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
AN1503 dihydrodipicolinate synthase-like protein AN1503; EC 4.-.-.- from Emericella nidulans (see paper)
25% identity, 77% coverage of query (49.7 bits)
SSA_0078 / A3CK37 N-acetylneuraminate lyase subunit (EC 4.1.3.3) from Streptococcus sanguinis (strain SK36) (see 3 papers)
24% identity, 93% coverage of query (48.5 bits)
NSAE_SPHXE / Q9X9Q6 Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase; THBPA hydratase-aldolase; 2'-hydroxybenzalpyruvate aldolase; EC 4.1.2.45 from Sphingobium xenophagum (see 2 papers)
Q9X9Q6 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45) from Sphingobium xenophagum (see paper)
24% identity, 80% coverage of query (47.8 bits)
Q9CKB0 N-acetylneuraminate lyase (EC 4.1.3.3) from Pasteurella multocida (see 2 papers)
22% identity, 98% coverage of query (46.6 bits)
1f74A / P44539 Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii complexed with 4-deoxy-sialic acid (see paper)
22% identity, 98% coverage of query (46.2 bits)
1f7bA Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii in complex with 4-oxo-sialic acid
22% identity, 98% coverage of query (46.2 bits)
4imgA / Q9CKB0 Crystal structure of pasteurella multocida n-acetyl-d-neuraminic acid lyase k164 mutant complexed with n-glycolylneuraminic acid (see paper)
21% identity, 98% coverage of query (45.4 bits)
4imfA Crystal structure of pasteurella multocida n-acetyl-d-neuraminic acid lyase k164 mutant complexed with n-acetylneuraminic acid
21% identity, 98% coverage of query (45.4 bits)
4hnnF / D7U7T8 Dihydrodipicolinate synthase from the common grapevine with pyruvate and lysine (see paper)
24% identity, 96% coverage of query (44.3 bits)
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Lawrence Berkeley National Laboratory