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Searching for up to 100 curated homologs for HSERO_RS13235 FitnessBrowser__HerbieS:HSERO_RS13235 (336 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

cobC / P21633 threonine-phosphate decarboxylase (EC 4.1.1.81) from Sinorhizobium sp. (see paper)
    42% identity, 98% coverage of query (200 bits)

cobD / P97084 L-threonine-O-3-phosphate decarboxylase subunit (EC 4.1.1.81) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
COBD_SALTY / P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 3 papers)
P97084 threonine-phosphate decarboxylase (EC 4.1.1.81) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    31% identity, 78% coverage of query (96.7 bits)

1lc7A / P97084 Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
    30% identity, 79% coverage of query (95.1 bits)

1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate
    30% identity, 79% coverage of query (95.1 bits)

1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica
    30% identity, 79% coverage of query (94.7 bits)

Build an alignment

Build an alignment for HSERO_RS13235 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

MmCobD / Q8PVB1 MmCobD (EC 4.1.1.81; EC 2.7.1.177) from Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (see 2 papers)
Q8PVB1 threonine-phosphate decarboxylase (EC 4.1.1.81) from Methanosarcina mazei (see paper)
    26% identity, 79% coverage of query (83.2 bits)

orf2651 / A0A0D3RBW0 tryptophan—pyruvate aminotransferase (EC 2.6.1.99) from Streptomyces griseus (see 2 papers)
    28% identity, 71% coverage of query (73.9 bits)

AZOBR_RS20485 histidinol-phosphate aminotransferase [EC:2.6.1.9] from Azospirillum brasilense Sp245
    27% identity, 71% coverage of query (72.8 bits)

3ly1D / Q6D4Z0 Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
    24% identity, 77% coverage of query (71.6 bits)

1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
    27% identity, 78% coverage of query (69.3 bits)

HisC / b2021 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hisC / P06986 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Escherichia coli (strain K12) (see 5 papers)
HIS8_ECOLI / P06986 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HPAT; HspAT; EC 2.6.1.9 from Escherichia coli (strain K12) (see 3 papers)
    27% identity, 72% coverage of query (68.6 bits)

1fg3A / P06986 Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
    27% identity, 72% coverage of query (68.2 bits)

HIS8_THEMA / Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    23% identity, 85% coverage of query (68.2 bits)

2f8jA / Q9X0D0 Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
    23% identity, 85% coverage of query (68.2 bits)

1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate
    27% identity, 72% coverage of query (68.2 bits)

1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    23% identity, 85% coverage of query (68.2 bits)

1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima
    23% identity, 85% coverage of query (68.2 bits)

1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form)
    23% identity, 85% coverage of query (68.2 bits)

BPHYT_RS14905 Aromatic-amino-acid transaminase (EC 2.6.1.57) from Burkholderia phytofirmans PsJN
    28% identity, 79% coverage of query (65.5 bits)

PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] from Phaeobacter inhibens BS107
    25% identity, 83% coverage of query (63.9 bits)

DVU1029 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Hildenborough JW710
    26% identity, 71% coverage of query (58.5 bits)

PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas putida KT2440
    23% identity, 87% coverage of query (57.8 bits)

Psest_3297 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas stutzeri RCH2
    25% identity, 84% coverage of query (57.4 bits)

Pf6N2E2_3251 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Pseudomonas fluorescens FW300-N2E2
    25% identity, 87% coverage of query (56.2 bits)

DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) from Desulfovibrio vulgaris Miyazaki F
    28% identity, 76% coverage of query (53.9 bits)

HIS8_TOBAC / O82030 Histidinol-phosphate aminotransferase, chloroplastic; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Nicotiana tabacum (Common tobacco) (see paper)
O82030 histidinol-phosphate transaminase (EC 2.6.1.9) from Nicotiana tabacum (see paper)
    25% identity, 82% coverage of query (51.6 bits)

HIS8_NICPL / Q9FEW2 Histidinol-phosphate aminotransferase, chloroplastic; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco) (see paper)
    25% identity, 82% coverage of query (50.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory