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Searching for up to 100 curated homologs for HSERO_RS14025 FitnessBrowser__HerbieS:HSERO_RS14025 (309 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMc01801 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sinorhizobium meliloti 1021
    52% identity, 98% coverage of query (316 bits)

argC / CAC29374.1 acetylglutamylphosphate reductase from Rhizobium etli (see paper)
    49% identity, 98% coverage of query (292 bits)

Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sphingomonas koreensis DSMZ 15582
    47% identity, 97% coverage of query (244 bits)

Build an alignment

Build an alignment for HSERO_RS14025 and 3 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

ARG56_SCHPO / P31318 Protein arg11, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
arg11 / GI|1204210 N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (see 2 papers)
    29% identity, 91% coverage of query (97.1 bits)

ARG5,6 arginine biosynthetic enzyme activities from Candida albicans (see 3 papers)
    27% identity, 84% coverage of query (94.0 bits)

CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) from Pedobacter sp. GW460-11-11-14-LB5
    27% identity, 82% coverage of query (93.2 bits)

ARGC_ARATH / Q93Z70 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Arabidopsis thaliana (Mouse-ear cress)
    30% identity, 96% coverage of query (92.4 bits)

Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
    30% identity, 82% coverage of query (92.4 bits)

ARGC_ORYSJ / Q6AV34 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Oryza sativa subsp. japonica (Rice) (see paper)
    30% identity, 83% coverage of query (90.5 bits)

BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Bacteroides thetaiotaomicron VPI-5482
    24% identity, 98% coverage of query (88.6 bits)

N515DRAFT_3769 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Dyella japonica UNC79MFTsu3.2
    28% identity, 96% coverage of query (86.7 bits)

argC / CAB82479.1 N-acetyl-gamma-glutamyl-phosphate reductase from Streptomyces clavuligerus (see 3 papers)
    32% identity, 82% coverage of query (86.7 bits)

ARG56_YEAST / Q01217 Protein ARG5,6, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
Q01217 acetylglutamate kinase (EC 2.7.2.8) from Saccharomyces cerevisiae (see paper)
ARG5,6 / CAA40336.1 acetylglutamate kinase from Saccharomyces cerevisiae (see paper)
    28% identity, 85% coverage of query (81.3 bits)

ARGC_GEOSE / Q07906 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
    27% identity, 84% coverage of query (74.3 bits)

P9WPZ9 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) from Mycobacterium tuberculosis (see paper)
    27% identity, 88% coverage of query (65.9 bits)

2i3gA / P9WPZ9 Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
    27% identity, 88% coverage of query (65.9 bits)

7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
    27% identity, 88% coverage of query (65.5 bits)

7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
    27% identity, 88% coverage of query (65.5 bits)

7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
    27% identity, 88% coverage of query (65.5 bits)

7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
    27% identity, 88% coverage of query (65.5 bits)

ArgC / b3958 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
argC / P11446 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli (strain K12) (see 4 papers)
ARGC_ECOLI / P11446 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Escherichia coli (strain K12) (see paper)
P11446 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) from Escherichia coli (see paper)
    28% identity, 94% coverage of query (64.7 bits)

Q5JFW1 [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Thermococcus kodakarensis (see paper)
    25% identity, 83% coverage of query (51.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory