Searching for up to 100 curated homologs for HSERO_RS14685 FitnessBrowser__HerbieS:HSERO_RS14685 (464 a.a.)
Found high-coverage hits (≥70%) to 52 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
argH / BAC65282.1 argininosuccinate lyase from Burkholderia multivorans (see paper)
80% identity, 97% coverage of query (749 bits)
ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102) (see paper)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp. (see paper)
49% identity, 98% coverage of query (456 bits)
Q8DVX5 argininosuccinate lyase (EC 4.3.2.1) from Streptococcus mutans (see paper)
49% identity, 98% coverage of query (454 bits)
2e9fB / Q5SLL0 Crystal structure of t.Th.Hb8 argininosuccinate lyase complexed with l-arginine
51% identity, 95% coverage of query (433 bits)
ArgH / b3960 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
argH / P11447 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli (strain K12) (see 2 papers)
47% identity, 96% coverage of query (414 bits)
1tj7B / P11447 Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. Coli (see paper)
47% identity, 95% coverage of query (410 bits)
argH(A) / CAB95024.1 argininosuccinase and n-acetylglutamate synthase from Moritella abyssi (see paper)
46% identity, 97% coverage of query (397 bits)
Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus (see paper)
45% identity, 98% coverage of query (394 bits)
ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas) (see 6 papers)
43% identity, 98% coverage of query (380 bits)
arg7 / RF|NP_595129.1 argininosuccinate lyase; EC 4.3.2.1 from Schizosaccharomyces pombe (see paper)
43% identity, 99% coverage of query (377 bits)
ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove) (see 2 papers)
44% identity, 97% coverage of query (375 bits)
1k7wD / P24058 Crystal structure of s283a duck delta 2 crystallin mutant (see paper)
44% identity, 95% coverage of query (373 bits)
ARG7 / CAA09001.1 argininosuccinate lyase from Chlamydomonas reinhardtii (see paper)
44% identity, 97% coverage of query (373 bits)
ASL / P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens (see 5 papers)
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human) (see 11 papers)
42% identity, 98% coverage of query (371 bits)
ARLY_MOUSE / Q91YI0 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Mus musculus (Mouse) (see paper)
42% identity, 98% coverage of query (369 bits)
ARLY_ANSAN / P33110 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Anser anser anser (Western greylag goose) (see 2 papers)
42% identity, 96% coverage of query (363 bits)
ARLY1_ANAPL / P24057 Delta-1 crystallin; Delta crystallin I from Anas platyrhynchos (Mallard) (Anas boschas) (see 4 papers)
42% identity, 96% coverage of query (362 bits)
1hy0A Crystal structure of wild type duck delta 1 crystallin (eye lens protein)
42% identity, 95% coverage of query (362 bits)
ARLY_YEAST / P04076 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
42% identity, 98% coverage of query (350 bits)
AN2914 arginosuccinate lyase (Eurofung) from Emericella nidulans (see paper)
41% identity, 98% coverage of query (349 bits)
argH / CAA88927.2 argininosuccinate lyase from Streptomyces clavuligerus (see 3 papers)
42% identity, 97% coverage of query (348 bits)
ARG4 argininosuccinate lyase from Candida albicans (see paper)
41% identity, 100% coverage of query (344 bits)
ARLY1_CHICK / P02521 Delta-1 crystallin; Delta crystallin I from Gallus gallus (Chicken) (see 2 papers)
40% identity, 97% coverage of query (338 bits)
ARLY1_MELGA / Q7SIE0 Delta-1 crystallin; Delta crystallin I from Meleagris gallopavo (Wild turkey) (see paper)
39% identity, 97% coverage of query (337 bits)
P9WPY7 argininosuccinate lyase (EC 4.3.2.1) from Mycobacterium tuberculosis (see 2 papers)
42% identity, 96% coverage of query (303 bits)
6ienB / P9WPY7 Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis (see paper)
42% identity, 93% coverage of query (293 bits)
6ienA Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
42% identity, 93% coverage of query (284 bits)
6ienC Substrate/product bound argininosuccinate lyase from mycobacterium tuberculosis
39% identity, 93% coverage of query (271 bits)
Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) from Echinicola vietnamensis KMM 6221, DSM 17526
38% identity, 78% coverage of query (243 bits)
CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) from Pedobacter sp. GW460-11-11-14-LB5
35% identity, 80% coverage of query (243 bits)
6g3fA / Q11KV9 Crystal structure of edds lyase in complex with fumarate (see paper)
32% identity, 91% coverage of query (201 bits)
6g3iA Crystal structure of edds lyase in complex with n-(2-aminoethyl) aspartic acid (aeaa)
32% identity, 91% coverage of query (201 bits)
6g3hA Crystal structure of edds lyase in complex with ss-edds
32% identity, 91% coverage of query (201 bits)
6g3gA Crystal structure of edds lyase in complex with succinate
32% identity, 91% coverage of query (201 bits)
BT3733 arginosuccinate lyase (EC 4.3.2.1) from Bacteroides thetaiotaomicron VPI-5482
32% identity, 78% coverage of query (196 bits)
N515DRAFT_3770 arginosuccinate lyase (EC 4.3.2.1) from Dyella japonica UNC79MFTsu3.2
33% identity, 77% coverage of query (160 bits)
Build an alignment for HSERO_RS14685 and 36 homologs with ≥ 30% identity
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MJ0929 / Q58339 adenylosuccinate lyase (EC 4.3.2.2) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
28% identity, 77% coverage of query (93.2 bits)
PUR8_BACSU / P12047 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; Glutamyl--tRNA ligase regulatory factor; EC 4.3.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
P12047 adenylosuccinate lyase (EC 4.3.2.2) from Bacillus subtilis (see paper)
purB / GI|143366 (glutamyl-trna synthetase regulatory factor); EC 4.3.2.2 from Bacillus subtilis (see 4 papers)
24% identity, 71% coverage of query (69.7 bits)
PUR8_STAAW / Q7A0G9 Adenylosuccinate lyase; ASL; Adenylosuccinase; ASase; EC 4.3.2.2 from Staphylococcus aureus (strain MW2) (see paper)
Q7A0G9 adenylosuccinate lyase (EC 4.3.2.2) from Staphylococcus aureus (see paper)
24% identity, 89% coverage of query (59.7 bits)
FUMC_MYCTU / P9WN93 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
P9WN93 fumarate hydratase (EC 4.2.1.2) from Mycobacterium tuberculosis (see paper)
24% identity, 70% coverage of query (59.3 bits)
4adlA Crystal structures of rv1098c in complex with malate
24% identity, 70% coverage of query (59.3 bits)
2x75A / Q7A0G9 Staphylococcus aureus adenylosuccinate lyase (see paper)
24% identity, 73% coverage of query (57.8 bits)
YBN5_SCHPO / O42889 Uncharacterized protein C8E4.05c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 88% coverage of query (57.8 bits)
4apbD / P9WN93 Crystal structure of mycobacterium tuberculosis fumarase (rv1098c) s318c in complex with fumarate (see paper)
23% identity, 70% coverage of query (57.4 bits)
6s7uA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(1h-indol-3-yl)acetamide
22% identity, 70% coverage of query (48.1 bits)
6s7kA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-(n-methylsulfamoyl) phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
22% identity, 70% coverage of query (48.1 bits)
6s43A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azocan-1-ylsulfonyl)-2- methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
22% identity, 70% coverage of query (48.1 bits)
5f91A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator (n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)
22% identity, 70% coverage of query (47.8 bits)
6s7zA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-((3,4-dihydroisoquinolin-2(1h)- yl)sulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl) acetamide
22% identity, 70% coverage of query (45.8 bits)
6s88A Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-((1,2,4,5-tetrahydro- 3h-benzo[d]azepin-3-yl)sulfonyl)phenyl)-2-(4-oxo-3,4- dihydrophthalazin-1-yl)acetamide
22% identity, 70% coverage of query (45.4 bits)
6s7wA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(5-(azepan-1-ylsulfonyl)-2- methoxyphenyl)-2-(quinolin-4-yl)acetamide
22% identity, 70% coverage of query (45.4 bits)
6s7sA Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator n-(2-methoxy-5-(n-phenylsulfamoyl) phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
22% identity, 70% coverage of query (45.4 bits)
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Lawrence Berkeley National Laboratory