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Searching for up to 100 curated homologs for HSERO_RS17000 FitnessBrowser__HerbieS:HSERO_RS17000 (423 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

Removed hits that are identical to the query, leaving 17

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5iaiA / B9JM84 Crystal structure of abc transporter solute binding protein arad_9887 from agrobacterium radiobacter k84, target efi-510945 in complex with ribitol
    31% identity, 87% coverage of query (137 bits)

TC 3.A.1.1.5 / O30831 SmoE, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
    30% identity, 83% coverage of query (124 bits)

Build an alignment

Build an alignment for HSERO_RS17000 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AO356_00025 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    29% identity, 87% coverage of query (124 bits)

Pf6N2E2_1963 ABC transporter for D-sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
    28% identity, 87% coverage of query (123 bits)

Ac3H11_2944 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Acidovorax sp. GW101-3H11
    31% identity, 76% coverage of query (117 bits)

mtlE / Q4KC57 polyol ABC-type transporter periplasmic substrate-binding protein from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    28% identity, 99% coverage of query (115 bits)

MANBP_PSEAE / Q9I1E0 Mannitol-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    29% identity, 84% coverage of query (111 bits)

BPHYT_RS16115 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
    29% identity, 77% coverage of query (111 bits)

PS417_12715 ABC transporter for D-Mannitol and D-Sorbitol, periplasmic substrate-binding protein from Pseudomonas simiae WCS417
    27% identity, 94% coverage of query (111 bits)

TC 3.A.1.1.49 / O30491 MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    29% identity, 74% coverage of query (109 bits)

Dshi_0547 ABC transporter for Xylitol, periplasmic substrate-binding component from Dinoroseobacter shibae DFL-12
    26% identity, 89% coverage of query (77.0 bits)

5ci5A / A8F7X5 Crystal structure of an abc transporter solute binding protein from thermotoga lettingae tmo (tlet_1705, target efi-510544) bound with alpha-d-tagatose
    24% identity, 83% coverage of query (72.8 bits)

TC 3.A.1.1.44 / Q7AKP1 Putative maltose-binding protein, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    27% identity, 74% coverage of query (59.3 bits)

4qrzA / A9CGI0 Crystal structure of sugar transporter atu4361 from agrobacterium fabrum c58, target efi-510558, with bound maltotriose
    23% identity, 85% coverage of query (54.7 bits)

4qsdA Crystal structure of atu4361 sugar transporter from agrobacterium fabrum c58, target efi-510558, with bound sucrose
    23% identity, 85% coverage of query (54.7 bits)

TC 3.A.1.1.25 / Q72H68 Trehalose/maltose-binding protein aka TT_C1627, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    25% identity, 72% coverage of query (53.5 bits)

TC 3.A.1.1.19 / Q8L126 PalE, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
palE / BAB96538.1 PalE from Agrobacterium tumefaciens (see 3 papers)
    23% identity, 76% coverage of query (49.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory