Sites on a Tree

 

Searching for up to 100 curated homologs for HSERO_RS17460 FitnessBrowser__HerbieS:HSERO_RS17460 (249 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
    52% identity, 99% coverage of query (249 bits)

6ihhA Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
    52% identity, 99% coverage of query (248 bits)

ASL5_SARSH / A0A2U8U2K8 Oxidoreductase asL5; Xenovulene A biosynthesis cluster protein L5; EC 1.1.1.- from Sarocladium schorii (Acremonium strictum (strain IMI 501407)) (see 4 papers)
    45% identity, 98% coverage of query (207 bits)

A0A2D0WG37 cyclohexanol dehydrogenase (EC 1.1.1.245) from Acidovorax sp. (see paper)
    41% identity, 99% coverage of query (155 bits)

5t2uA / A0R723 Short chain dehydrogenase/reductase family protein (see paper)
    41% identity, 99% coverage of query (154 bits)

A0R723 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); acetoacetyl-CoA reductase (EC 1.1.1.36) from Mycolicibacterium smegmatis (see paper)
    41% identity, 99% coverage of query (153 bits)

4nbuB Crystal structure of fabg from bacillus sp (see paper)
    38% identity, 97% coverage of query (152 bits)

ARP2_METMF / A0A0B4HVU2 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium majus (strain ARSEF 297) (see paper)
    39% identity, 96% coverage of query (148 bits)

4esoB / Q92N93 Crystal structure of a putative oxidoreductase protein from sinorhizobium meliloti 1021 in complex with NADP
    39% identity, 97% coverage of query (148 bits)

ARP2_METGA / A0A0B4GU97 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium guizhouense (strain ARSEF 977) (see paper)
    38% identity, 96% coverage of query (147 bits)

ARP2_METBS / A0A0B4FP77 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium brunneum (strain ARSEF 3297) (see paper)
    38% identity, 96% coverage of query (147 bits)

ARP2_METRA / E9ET40 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23)) (see paper)
    38% identity, 96% coverage of query (147 bits)

ARP2_METAF / A0A0B4GT47 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium anisopliae (strain ARSEF 549) (see paper)
    38% identity, 96% coverage of query (145 bits)

ARP2_METAQ / E9EHG1 Hydroxynaphthalene reductase-like protein Arp2; EC 1.1.-.- from Metarhizium acridum (strain CQMa 102) (see paper)
    37% identity, 96% coverage of query (144 bits)

Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa (see paper)
    37% identity, 99% coverage of query (143 bits)

A1IG83 (R)-aminopropanol dehydrogenase (EC 1.1.1.75) from Rhodococcus erythropolis (see paper)
    39% identity, 99% coverage of query (142 bits)

GMDH_GLUOX / Q5FPE5 Glucose 1-dehydrogenase; EC 1.1.1.119 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
    40% identity, 97% coverage of query (142 bits)

AGN6_PAEDI / A0A411PQN6 Short chain dehydrogenase AgnL6; Agnestins biosynthesis cluster protein L6; EC 1.1.1.- from Paecilomyces divaricatus (Penicillium divaricatum) (see paper)
    37% identity, 98% coverage of query (139 bits)

cpnA / Q8GAV9 cyclopentanol dehydrogenase (EC 1.1.1.163) from Comamonas sp. (strain NCIMB 9872) (see 2 papers)
CPNA_COMS9 / Q8GAV9 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas sp. (strain NCIMB 9872) (see paper)
CPNA_COMTE / Q937L4 Cyclopentanol dehydrogenase; Cyclohexanol dehydrogenase; EC 1.1.1.163; EC 1.1.1.245 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
cpmB / CAD10799.1 cyclohexanol dehydrogenase from Comamonas testosteroni (see paper)
    38% identity, 98% coverage of query (139 bits)

GME73_PESMI / A0A5B8YU81 Short-chain dehydrogenase/reductase GME11373; Dibenzodioxocinones biosynthesis cluster protein GME11373; EC 1.1.1.- from Pestalotiopsis microspora (see 2 papers)
    36% identity, 98% coverage of query (137 bits)

8hfkA Crystal structure of cbar mutant (h162f) in complex with NADP+ and halogenated aryl ketone
    36% identity, 98% coverage of query (137 bits)

salM / B0L7F4 5-chloro-5-deoxy-D-ribose 1-dehydrogenase from Salinispora tropica (see 2 papers)
    37% identity, 98% coverage of query (136 bits)

BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) from Burkholderia phytofirmans PsJN
    37% identity, 99% coverage of query (135 bits)

7ejhA / Q6WVP7 Crystal structure of kred mutant-f147l/l153q/y190p/l199a/m205f/m206f and 2-hydroxyisoindoline-1,3-dione complex
    36% identity, 100% coverage of query (134 bits)

7yb2D / A0A2G5I2X5 Crystal structure of anthrol reductase (cbar) in complex with NADP+ and emodin (see paper)
    35% identity, 98% coverage of query (134 bits)

4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
    37% identity, 96% coverage of query (134 bits)

CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
    37% identity, 96% coverage of query (133 bits)

TPRL1_ERYCB / H9BFQ0 Tropinone reductase-like 1; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
    35% identity, 98% coverage of query (133 bits)

3pk0B / A0QQJ6 Crystal structure of short-chain dehydrogenase/reductase sdr from mycobacterium smegmatis (see paper)
    37% identity, 98% coverage of query (132 bits)

A0A0M4UR95 L-xylulose reductase (EC 1.1.1.10) from Rhizomucor pusillus (see paper)
    34% identity, 98% coverage of query (132 bits)

RADH_LENKE / Q6WVP7 NADP-dependent (R)-specific alcohol dehydrogenase; (R)-specific ADH; Ketoreductase; KRED; EC 1.1.1.- from Lentilactobacillus kefiri (Lactobacillus kefiri)
    37% identity, 100% coverage of query (132 bits)

7ejiB Crystal structure of kred f147l/l153q/y190p/l199a/m205f/m206f variant and methyl methacrylate complex
    36% identity, 98% coverage of query (132 bits)

8hfjC Crystal structure of cbar mutant (h162f) in complex with NADP+ and a bulky 1,3-cyclodiketone
    35% identity, 98% coverage of query (132 bits)

RDT1_ELSFA / B0ZT44 Elsinochrome reductase 1; Elsinochromes biosynthesis cluster protein RDT1; EC 1.1.1.- from Elsinoe fawcettii (Citrus scab fungus) (Sphaceloma fawcettii) (see paper)
    33% identity, 98% coverage of query (131 bits)

BPHYT_RS34215 2-keto-3-deoxy-L-fuconate 4-dehydrogenase FucDH from Burkholderia phytofirmans PsJN
    36% identity, 98% coverage of query (130 bits)

TPRL2_ERYCB / H9BFQ1 Tropinone reductase-like 2; EC 1.1.1.- from Erythroxylum coca (Coca plant) (see paper)
    35% identity, 98% coverage of query (130 bits)

T4HR_ZYMTI / F9XMW6 Probable tetrahydroxynaphthalene reductase MYCGRDRAFT_87994; Conidial pigment biosynthesis cluster 29 protein MYCGRDRAFT_87994; EC 1.1.1.252 from Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici) (see paper)
    33% identity, 98% coverage of query (130 bits)

6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
    34% identity, 99% coverage of query (130 bits)

DMR18_CRYX8 / A0A4P8DJW8 Short chain dehydrogenase/reductase dmxR18; SDR dmsR18; Dimeric xanthone biosynthesis cluster protein R18; EC 1.3.1.- from Cryptosporiopsis sp. (strain 8999) (see paper)
    36% identity, 98% coverage of query (129 bits)

7v0hG / B4E6Z1 Crystal structure of putative glucose 1-dehydrogenase from burkholderia cenocepacia in complex with NADP and a potential reaction product
    38% identity, 98% coverage of query (129 bits)

BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
    38% identity, 98% coverage of query (129 bits)

DHRS6_DANRE / Q561X9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
Q561X9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Danio rerio (see paper)
    34% identity, 97% coverage of query (129 bits)

6y0sAAA / Q84EX5 6y0sAAA (see paper)
    34% identity, 99% coverage of query (129 bits)

6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
    34% identity, 98% coverage of query (129 bits)

1zk4A Structure of r-specific alcohol dehydrogenase (wildtype) from lactobacillus brevis in complex with acetophenone and NADP
    34% identity, 99% coverage of query (129 bits)

fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
    35% identity, 98% coverage of query (128 bits)

W5VJT8 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    32% identity, 98% coverage of query (128 bits)

T4HR_PYRO7 / Q12634 Tetrahydroxynaphthalene reductase; T4HN reductase; THNR; EC 1.1.1.252 from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae) (see 2 papers)
Q12634 tetrahydroxynaphthalene reductase (EC 1.1.1.252) from Pyricularia oryzae (see paper)
BUF1 trihydroxynaphthalene reductase from Magnaporthe grisea 70-15 (see paper)
    32% identity, 98% coverage of query (127 bits)

tsaC / P94681 4-sulfobenzyl alcohol dehydrogenase subunit (EC 1.1.1.257) from Comamonas testosteroni (see paper)
TSAC_COMTE / P94681 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2; Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; EC 1.2.1.62 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
    33% identity, 97% coverage of query (127 bits)

4fj0D / O93874 Crystal structure of the ternary complex between a fungal 17beta- hydroxysteroid dehydrogenase (holo form) and 3,7-dihydroxy flavone (see paper)
    34% identity, 98% coverage of query (127 bits)

O93874 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Curvularia lunata (see 2 papers)
    34% identity, 98% coverage of query (127 bits)

DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human) (see 7 papers)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see paper)
    33% identity, 99% coverage of query (127 bits)

1g0oC / Q12634 Structure of trihydroxynaphthalene reductase in complex with NADPH and pyroquilon (see paper)
    32% identity, 98% coverage of query (127 bits)

xecD / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase subunit (EC 1.1.1.268) from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 5 papers)
HCDR1_XANP2 / Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase; R-HPCDH; 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase; Aliphatic epoxide carboxylation component III; Epoxide carboxylase component III; RHPCDH1; EC 1.1.1.268 from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) (see 7 papers)
Q56840 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268) from Xanthobacter autotrophicus (see 4 papers)
2cfcA / Q56840 Structural basis for stereo selectivity in the (r)- and (s)-hydroxypropylethane thiosulfonate dehydrogenases (see paper)
    35% identity, 97% coverage of query (127 bits)

DHRS4_RABIT / Q9GKX2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; RACR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal short-chain alcohol dehydrogenase; PSCD; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; rabNRDR; EC 1.1.1.184; EC 1.1.1.300 from Oryctolagus cuniculus (Rabbit) (see 3 papers)
    33% identity, 96% coverage of query (127 bits)

mdpC / Q5BH34 tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one reductase from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see 2 papers)
MDPC_EMENI / Q5BH34 Short chain dehydrogenase mdpC; Monodictyphenone synthesis protein C; EC 1.3.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 5 papers)
mdpC Oxidoreductase, putative (Eurofung) from Emericella nidulans (see paper)
    35% identity, 98% coverage of query (127 bits)

RUMGNA_02133 / A7B3K3 chenodeoxycholate 3α-dehydrogenase (EC 1.1.1.392) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3AHDP_RUMGV / A7B3K3 3alpha-hydroxysteroid dehydrogenase; 3alpha-HSDH; 3alpha-hydroxycholanate dehydrogenase (NADP(+)); NADP-dependent bile acid 3alpha-dehydrogenase; EC 1.1.1.-; EC 1.1.1.392 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
    36% identity, 99% coverage of query (127 bits)

VER1_DOTSE / Q8TFD5 Versicolorin reductase 1; VER-1; Dothistromin biosynthesis protein A; EC 1.1.-.- from Dothistroma septosporum (Red band needle blight fungus) (Mycosphaerella pini) (see 6 papers)
VER1_DOTSN / M2WJF1 Versicolorin reductase 1; VER-1; Dothistromin biosynthesis protein A; EC 1.1.-.- from Dothistroma septosporum (strain NZE10 / CBS 128990) (Red band needle blight fungus) (Mycosphaerella pini) (see 7 papers)
    33% identity, 98% coverage of query (127 bits)

PFMAI_PESFW / W3XC32 Trihydroxynaphthalene reductase PfmaI; Conidial pigment biosynthesis protein I; EC 1.1.1.- from Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) (see 2 papers)
    32% identity, 96% coverage of query (127 bits)

4fj1B Crystal structure of the ternary complex between a fungal 17beta- hydroxysteroid dehydrogenase (holo form) and genistein
    34% identity, 98% coverage of query (127 bits)

4fj2B Crystal structure of the ternary complex between a fungal 17beta- hydroxysteroid dehydrogenase (holo form) and biochanin a
    34% identity, 98% coverage of query (127 bits)

3qwiA Crystal structure of a 17beta-hydroxysteroid dehydrogenase (holo form) from fungus cochliobolus lunatus in complex with NADPH and coumestrol
    34% identity, 98% coverage of query (127 bits)

3qwhA Crystal structure of the 17beta-hydroxysteroid dehydrogenase from cochliobolus lunatus in complex with NADPH and kaempferol
    34% identity, 98% coverage of query (127 bits)

1ybvA Structure of trihydroxynaphthalene reductase in complex with NADPH and an active site inhibitor
    32% identity, 98% coverage of query (127 bits)

1g0nA Structure of trihydroxynaphthalene reductase in complex with NADPH and 4,5,6,7-tetrachloro-phthalide
    32% identity, 98% coverage of query (127 bits)

1dohA Structure of trihydroxynaphthalene reductase in complex with NADPH and 4-nitro-inden-1-one
    32% identity, 98% coverage of query (127 bits)

3o4rA / Q9BTZ2 Crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4)
    33% identity, 96% coverage of query (126 bits)

1zk1A Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    34% identity, 99% coverage of query (126 bits)

1zjzA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and NAD
    34% identity, 99% coverage of query (126 bits)

1zjyA Structure of r-specific alcohol dehydrogenase (mutant g37d) from lactobacillus brevis in complex with phenylethanol and nadh
    34% identity, 99% coverage of query (126 bits)

W5VJM4 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens var. hirtella (see paper)
    33% identity, 98% coverage of query (125 bits)

barS1 / Q9LBV3 A-factor type γ-butyrolactone 6-reductase (6S-forming) monomer (EC 1.1.1.413) from Streptomyces virginiae (see paper)
BARS1_STRVG / Q9LBV3 A-factor type gamma-butyrolactone 1'-reductase (1S-forming); 6-dehydro-VB-A reductase; Butyrolactone autoregulator synthesis; EC 1.1.1.413 from Streptomyces virginiae (Streptomyces cinnamonensis) (see 2 papers)
    34% identity, 97% coverage of query (125 bits)

AACUN_ASPA1 / A0A1L9WLH9 Short chain dehydrogenase/reductase AacuN; SDR AacuN; Secalonic acid biosynthesis cluster protein N; EC 1.3.1.- from Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094) (see 6 papers)
    36% identity, 96% coverage of query (125 bits)

ver-1 / AAS90099.1 Ver-1 from Aspergillus flavus (see paper)
    33% identity, 98% coverage of query (125 bits)

1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
    34% identity, 99% coverage of query (125 bits)

1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
    34% identity, 99% coverage of query (125 bits)

W5VJJ6 isopiperitenol dehydrogenase (EC 1.1.1.223) from Perilla frutescens (see paper)
    33% identity, 98% coverage of query (124 bits)

AFO85456.1 reductase/oxidase from Marinactinospora thermotolerans (see paper)
    37% identity, 97% coverage of query (124 bits)

aflM / P50161 tetrahydroxy-7,9-dioxapentacycloicosaheptenone 16-reductase from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) (see 8 papers)
AFLM_ASPPU / P50161 Versicolorin reductase 1; VER-1; Aflatoxin biosynthesis protein M; EC 1.3.1.- from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) (see 8 papers)
    33% identity, 98% coverage of query (124 bits)

A0A2K9VPX3 D-arabinitol 4-dehydrogenase (EC 1.1.1.11) from Gluconobacter sp. JX-05 (see paper)
    35% identity, 97% coverage of query (124 bits)

7djsD / A0A554HE32 Crystal structure of isopiperitenol dehydrogenase from pseudomonas aeruginosa complexed with NAD
    37% identity, 99% coverage of query (124 bits)

6pejA / Q92N06 Structure of sorbitol dehydrogenase from sinorhizobium meliloti 1021 bound to sorbitol
    36% identity, 98% coverage of query (123 bits)

TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
    33% identity, 96% coverage of query (123 bits)

4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
    38% identity, 98% coverage of query (122 bits)

1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
    33% identity, 96% coverage of query (122 bits)

YLX6_SCHPO / Q9URX0 Uncharacterized oxidoreductase C922.06; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    33% identity, 98% coverage of query (122 bits)

ARP2_ASPFU / E9QUT3 Hydroxynaphthalene reductase arp2; Conidial pigment biosynthesis oxidase arp2; EC 1.1.-.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 9 papers)
    35% identity, 94% coverage of query (122 bits)

2zatA / Q8WNV7 Crystal structure of a mammalian reductase (see paper)
    31% identity, 98% coverage of query (122 bits)

Q5FNX9 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Gluconobacter oxydans (see paper)
    34% identity, 97% coverage of query (122 bits)

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis (see paper)
    38% identity, 97% coverage of query (122 bits)

DHRS4_PIG / Q8WNV7 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal carbonyl reductase; PerCR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; EC 1.1.1.184; EC 1.1.1.300 from Sus scrofa (Pig) (see 3 papers)
    31% identity, 98% coverage of query (121 bits)

DHRS6_MOUSE / Q8JZV9 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Mus musculus (Mouse) (see 3 papers)
Q8JZV9 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Mus musculus (see paper)
    33% identity, 97% coverage of query (121 bits)

PIG7_CLAP2 / M1W270 Short chain dehydrogenase CPUR_05429; Ergochrome gene cluster protein CPUR_05429; EC 1.1.1.- from Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum) (see 2 papers)
    33% identity, 98% coverage of query (121 bits)

L7QI79 tropinone reductase I (EC 1.1.1.206) from Withania coagulans (see paper)
    34% identity, 96% coverage of query (121 bits)

Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
    35% identity, 96% coverage of query (121 bits)

FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
    35% identity, 96% coverage of query (121 bits)

3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
    36% identity, 96% coverage of query (121 bits)

DHRS6_RAT / D4A1J4 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Rattus norvegicus (Rat) (see paper)
    33% identity, 97% coverage of query (120 bits)

TRN1_COCOF / A7DY56 Tropinone reductase; EC 1.1.1.206; EC 1.1.1.236 from Cochlearia officinalis (Common scurvygrass) (see paper)
A7DY56 tropinone reductase I (EC 1.1.1.206); tropinone reductase II (EC 1.1.1.236) from Cochlearia officinalis (see paper)
    34% identity, 97% coverage of query (120 bits)

1xkqA / Q9N5G4 Crystal structure of short-chain dehydrogenase/reductase of unknown function from caenorhabditis elegans with cofactor
    33% identity, 99% coverage of query (120 bits)

Build an alignment

Build an alignment for HSERO_RS17460 and 100 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory