Searching for up to 100 curated homologs for HSERO_RS19250 HSERO_RS19250 glutamate ABC transporter permease (249 a.a.)
Found high-coverage hits (≥70%) to 36 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.3.22 / Q9I403 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
49% identity, 97% coverage of query (229 bits)
Pf1N1B4_772 ABC transporter for L-asparagine and L-glutamate, permease component 1 from Pseudomonas fluorescens FW300-N1B4
51% identity, 97% coverage of query (219 bits)
AO353_16285 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
49% identity, 97% coverage of query (218 bits)
PfGW456L13_4771 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 1 from Pseudomonas fluorescens GW456-L13
49% identity, 97% coverage of query (214 bits)
GltJ / b0654 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GltJ / P0AER3 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
GLTJ_ECOLI / P0AER3 Glutamate/aspartate import permease protein GltJ from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER3 Glutamate/aspartate transport system permease protein GltJ aka B0654, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
43% identity, 97% coverage of query (212 bits)
TC 3.A.1.3.19 / Q88NY3 PP1070, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
48% identity, 97% coverage of query (210 bits)
TC 3.A.1.3.16 / A1VZQ3 PEP1B, component of Uptake system for glutamate and aspartate from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
31% identity, 91% coverage of query (109 bits)
TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
34% identity, 82% coverage of query (107 bits)
TC 3.A.1.3.22 / Q9I404 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
32% identity, 86% coverage of query (103 bits)
PfGW456L13_4772 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 2 from Pseudomonas fluorescens GW456-L13
31% identity, 88% coverage of query (100 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
32% identity, 86% coverage of query (100 bits)
Pf1N1B4_773 ABC transporter for L-asparagine and L-glutamate, permease subunit 2 from Pseudomonas fluorescens FW300-N1B4
31% identity, 88% coverage of query (98.2 bits)
TC 3.A.1.3.19 / Q88NY4 PP1069, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
30% identity, 88% coverage of query (96.7 bits)
AO356_00470 ABC transporter for D-Glucosamine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
Pf6N2E2_2051 ABC transporter for D-Glucosamine Hydrochloride, permease component 1 from Pseudomonas fluorescens FW300-N2E2
33% identity, 86% coverage of query (96.7 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
31% identity, 82% coverage of query (94.7 bits)
AO353_16280 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 1 from Pseudomonas fluorescens FW300-N2E3
30% identity, 84% coverage of query (94.4 bits)
Build an alignment for HSERO_RS19250 and 16 homologs with ≥ 30% identity
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GltK / b0653 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
GltK / P0AER5 glutamate/aspartate ABC transporter membrane subunit GltK (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTK_ECOLI / P0AER5 Glutamate/aspartate import permease protein GltK from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER5 Glutamate/aspartate transport system permease protein GltK aka B0653, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
28% identity, 93% coverage of query (94.4 bits)
TcyL / b1918 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
tcyL / P0AFT2 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli (strain K12) (see 3 papers)
TCYL_ECOLI / P0AFT2 L-cystine transport system permease protein TcyL from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.3.10 / P0AFT2 Inner membrane amino-acid ABC transporter permease protein YECS CysY aka B1918, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 4 papers)
30% identity, 83% coverage of query (93.2 bits)
AO353_21720 ABC transporter for D-glucosamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
32% identity, 86% coverage of query (92.4 bits)
4ymwC Crystal structure of an amino acid abc transporter with histidines
29% identity, 86% coverage of query (88.6 bits)
GlnP / b0810 L-glutamine ABC transporter membrane subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GlnP / P0AEQ6 L-glutamine ABC transporter membrane subunit (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.2 / P0AEQ6 Glutamine transport system permease protein GlnP aka B0810, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 5 papers)
29% identity, 92% coverage of query (88.2 bits)
YXEN_BACSU / P54953 Probable amino-acid permease protein YxeN from Bacillus subtilis (strain 168) (see paper)
29% identity, 92% coverage of query (88.2 bits)
4ymtC / Q8RCC3 Crystal structure of an amino acid abc transporter complex with arginines (see paper)
29% identity, 86% coverage of query (88.2 bits)
Ac3H11_2554 ABC transporter for L-Histidine, permease component 1 from Acidovorax sp. GW101-3H11
29% identity, 86% coverage of query (88.2 bits)
AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
30% identity, 91% coverage of query (85.9 bits)
GLNM_BACSU / O34671 Probable glutamine ABC transporter permease protein GlnM from Bacillus subtilis (strain 168) (see paper)
28% identity, 83% coverage of query (85.5 bits)
ArtM / b0861 L-arginine ABC transporter membrane subunit ArtM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see paper)
ArtM / P0AE30 L-arginine ABC transporter membrane subunit ArtM (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
ARTM_ECOLI / P0AE30 Arginine ABC transporter permease protein ArtM from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.3 / P0AE30 Arginine transport system permease protein ArtM aka B0861, component of Arginine porter from Escherichia coli (see 6 papers)
31% identity, 85% coverage of query (84.7 bits)
TC 3.A.1.3.6 / P35113 NocM aka ATU6025 aka AGR_PTI_65, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
31% identity, 83% coverage of query (82.4 bits)
ARGU_CORGL / Q8NQU3 Arginine transport system permease protein ArgU from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
30% identity, 81% coverage of query (81.6 bits)
TC 3.A.1.3.5 / P35114 OCM1 aka OccM, component of Octopine porter from Agrobacterium tumefaciens (see 2 papers)
28% identity, 83% coverage of query (81.6 bits)
TC 3.A.1.3.21 / Q9I487 Amino acid ABC transporter membrane protein, component of Hydroxy L-proline uptake porter, HprABC from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
31% identity, 84% coverage of query (81.6 bits)
SMc00139 L-lysine ABC transporter, permease component 1 from Sinorhizobium meliloti 1021
27% identity, 85% coverage of query (80.1 bits)
AO353_03050 ABC transporter for L-Arginine and L-Citrulline, permease component 2 from Pseudomonas fluorescens FW300-N2E3
28% identity, 87% coverage of query (78.6 bits)
Pf1N1B4_3433 ABC transporter for L-Arginine and L-Citrulline, permease component 2 from Pseudomonas fluorescens FW300-N1B4
27% identity, 91% coverage of query (78.6 bits)
TC 3.A.1.3.11 / O50183 AotP aka AotM aka PA0890, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
29% identity, 72% coverage of query (77.8 bits)
BPHYT_RS24010 L-histidine ABC transporter, permease component 2 from Burkholderia phytofirmans PsJN
27% identity, 92% coverage of query (77.8 bits)
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Lawrence Berkeley National Laboratory