Sites on a Tree

 

Searching for up to 100 curated homologs for HSERO_RS19360 FitnessBrowser__HerbieS:HSERO_RS19360 (391 a.a.)

Found high-coverage hits (≥70%) to 5 curated proteins.

Removed hits that are identical to the query, leaving 4

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMa0247 2-dehydro-3-deoxy-D-arabinonate dehydratase, 2,4-dioxopentanoate forming from Sinorhizobium meliloti 1021
    59% identity, 99% coverage of query (449 bits)

Ga0059261_1895 2-keto-3-deoxyxylonate dehydratase (EC 4.2.1.141) from Sphingomonas koreensis DSMZ 15582
    57% identity, 97% coverage of query (423 bits)

CCNA_00866 2-keto-3-deoxyxylonate dehydratase XylX (EC 4.2.1.141) from Caulobacter crescentus NA1000
xylX / A0A0H3C4T2 2-dehydro-3-deoxy-D-arabinonate dehydratase (EC 4.2.1.141) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 7 papers)
    55% identity, 97% coverage of query (403 bits)

Build an alignment

Build an alignment for HSERO_RS19360 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

xacE / D4GP28 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43; EC 4.2.1.141) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
KDXD_HALVD / D4GP28 Probable 2-keto-3-deoxyxylonate dehydratase; KDXD; EC 4.2.1.141 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    25% identity, 82% coverage of query (90.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory