Searching for up to 100 curated homologs for HSERO_RS19525 FitnessBrowser__HerbieS:HSERO_RS19525 (157 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PtsN / b3204 phosphotransferase system enzyme IIA(Ntr) from Escherichia coli K-12 substr. MG1655 (see 22 papers)
ptsN / AAB60165.1 Enzyme IIANtr from Escherichia coli (see 3 papers)
    35% identity, 83% coverage of query (82.4 bits)

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Build an alignment for HSERO_RS19525 and 1 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 4.A.2.1.20 / Q3K0G6 Chromosomal fructose Enzyme IIABC (Fru1) of 654 aas; in an operon with fructose-1-P kinase from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
    29% identity, 85% coverage of query (72.8 bits)

TC 4.A.2.1.14 / D2RXA7 Putative PTS IIA-like nitrogen-regulatory protein PtsN, component of Fructose Enzyme II complex (IIAFru - IIBFru - IICFru) (based on homology) from Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) (see paper)
    32% identity, 84% coverage of query (72.4 bits)

TC 4.A.2.1.9 / Q1R4S9 Putative phosphotransferase system (PTS), fructose-specific, component of The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence from Escherichia coli (strain UTI89 / UPEC) (see paper)
    29% identity, 87% coverage of query (69.7 bits)

TC 4.A.2.1.7 / Q1LZ59 The fructose inducible fructose/xylitol porter, FruI from Streptococcus mutans UA159 (see paper)
    30% identity, 85% coverage of query (69.7 bits)

tagM / A0A1Y0YTF1 tagatose-specific PTS enzyme IIA component from Bacillus licheniformis (see 2 papers)
TC 4.A.2.1.23 / T5HNP5 PTS fructose transporter subunit IIA, component of The tagatose-1-P-forming tagatose phosphorylating Enzyme IIA/IIBC, TagM/L (Van der Heiden et al. 2015). The product is phosphorylated by tagatose-1-P kinase (TagK), and then cleaved by tagatose-1,6-bisphosphate aldolase (GatY) from Bacillus licheniformis CG-B52
    28% identity, 86% coverage of query (65.9 bits)

TC 4.A.2.1.4 / P71012 The fructose porter, FruA (fructose-1-P forming IIABC) (Delobbe et al. 1975) FruA is 39% identical to 4.A.2.1.1). fructose can be metabolized to Fru-1-P via this system as well as Fru-6-P by another PTS system from Bacillus subtilis (see paper)
    26% identity, 89% coverage of query (60.1 bits)

Q8DWE6 protein-Npi-phosphohistidine-D-fructose phosphotransferase (subunit 1/2) (EC 2.7.1.202) from Streptococcus mutans serotype c (see paper)
TC 4.A.2.1.8 / Q1LZ68 Constitutive fructose permease aka FruD, component of The constitutive fructose porter FruC/FruD from Streptococcus mutans UA159 (see paper)
    29% identity, 78% coverage of query (59.7 bits)

FryA / b2383 putative PTS multiphosphoryl transfer protein FryA from Escherichia coli K-12 substr. MG1655 (see 4 papers)
fryA / RF|NP_416884 multiphosphoryl transfer protein 1 from Escherichia coli K12 (see paper)
    30% identity, 81% coverage of query (59.7 bits)

TC 4.A.2.1.22 / Q3JZE3 PTS system, fructose-specific, IIA component, component of D-allose/D-ribose transporting Enzyme II complex (Fru2; IIA/IIB/IIC) (Patron et al. 2017). This system is similar to Frz of E. coli (TC#4.A.2.1.9) which is involved in environmental sensing, host adaptation and virulence from Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700)
    26% identity, 76% coverage of query (55.8 bits)

TC 4.A.2.1.5 / C0H3V2 Mannitol-specific phosphotransferase enzyme IIA component, component of The mannitol porter (MtlA) (mannitol-1-P forming), MtlAF from Bacillus subtilis (strain 168)
    31% identity, 78% coverage of query (52.8 bits)

C0H3V2 Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component from Bacillus subtilis (strain 168)
    31% identity, 78% coverage of query (52.8 bits)

TC 4.A.2.1.19 / M7QAG8 PTS system tagatose-specific IIA-TPr component, component of The tagatose-specific PTS transporter/kinase, TagIIA-TPr/TagIIB'BC (tagatose-1-P forming) from Klebsiella pneumoniae ATCC BAA-2146
    29% identity, 86% coverage of query (50.1 bits)

PTMA_STACT / P17876 Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component from Staphylococcus carnosus (strain TM300) (see paper)
    27% identity, 90% coverage of query (45.1 bits)

MANR_BACSU / O31644 Transcriptional regulator ManR; Mannose operon transcriptional activator; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see 2 papers)
    27% identity, 83% coverage of query (42.0 bits)

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