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Searching for up to 100 curated homologs for HSERO_RS20090 FitnessBrowser__HerbieS:HSERO_RS20090 (305 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

dhaL / Q0K7D4 L-dehydro-ascorbate lactonase from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see 2 papers)
    48% identity, 94% coverage of query (276 bits)

3e5zA / Q9RXN3 X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
    39% identity, 92% coverage of query (196 bits)

3dr2A / B0RN69 Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
    40% identity, 90% coverage of query (195 bits)

gnl / Q01578 gluconolactonase subunit (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
GNL_ZYMMO / Q01578 Gluconolactonase; D-glucono-delta-lactone lactonohydrolase; EC 3.1.1.17 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q01578 gluconolactonase (EC 3.1.1.17) from Zymomonas mobilis subsp. mobilis (see paper)
    31% identity, 94% coverage of query (137 bits)

Build an alignment

Build an alignment for HSERO_RS20090 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

B2LYJ5 1,4-lactonase (EC 3.1.1.25) from Fusarium proliferatum (see paper)
    26% identity, 99% coverage of query (114 bits)

xacC / D4GP31 D-xylono/L-arabinono-1,4-lactonase (EC 3.1.1.15; EC 3.1.1.68) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 5 papers)
XACC_HALVD / D4GP31 Pentonolactonase XacC; L-arabinonolactonase; Xylono-1,4-lactonase; EC 3.1.1.15; EC 3.1.1.68 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP31 L-arabinonolactonase (EC 3.1.1.15); xylono-1,4-lactonase (EC 3.1.1.68) from Haloferax volcanii (see 2 papers)
    28% identity, 85% coverage of query (95.9 bits)

uxuL / B2UIY8 D-galactaro-1,5-lactonase/D-glucaro-1,5-lactonase from Ralstonia pickettii (strain 12J) (see paper)
    26% identity, 90% coverage of query (72.0 bits)

PP_1170 D-glucaro-1,5-lactonase UxuL from Pseudomonas putida KT2440
    27% identity, 83% coverage of query (70.9 bits)

PS417_17365 galactaro-1,5-lactonase from Pseudomonas simiae WCS417
    29% identity, 83% coverage of query (68.6 bits)

Ga0059261_1893 Xylonolactonase (EC 3.1.1.68) from Sphingomonas koreensis DSMZ 15582
    31% identity, 90% coverage of query (68.2 bits)

ORYL_ASPOR / Q2TXF9 Lactonohydrolase oryL; Oryzines biosynthesis cluster protein L; EC 3.1.1.- from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
    24% identity, 82% coverage of query (68.2 bits)

PfGW456L13_2118 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas fluorescens GW456-L13
    26% identity, 85% coverage of query (60.8 bits)

7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate
    26% identity, 87% coverage of query (60.5 bits)

8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone
    27% identity, 88% coverage of query (58.9 bits)

8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product
    27% identity, 88% coverage of query (58.9 bits)

8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate
    27% identity, 88% coverage of query (58.9 bits)

7rizA / Q6N3R9 Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
    25% identity, 87% coverage of query (58.2 bits)

Pf1N1B4_413 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas fluorescens FW300-N1B4
    27% identity, 84% coverage of query (55.8 bits)

Shewana3_2088 L-arabinolactonase (EC 3.1.1.15) from Shewanella sp. ANA-3
    26% identity, 85% coverage of query (54.7 bits)

7plbB / Q9A9Z1 Caulobacter crescentus xylonolactonase with d-xylose (see paper)
    26% identity, 87% coverage of query (53.5 bits)

xylC / A0A0H3C6P8 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 2 papers)
XYLC_CAUVC / Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 4 papers)
Q9A9Z1 xylono-1,5-lactonase (EC 3.1.1.110) from Caulobacter vibrioides (see 4 papers)
    26% identity, 87% coverage of query (53.5 bits)

7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone
    26% identity, 87% coverage of query (53.5 bits)

PS417_11020 L-arabinolactonase (EC 3.1.1.15) from Pseudomonas simiae WCS417
    25% identity, 84% coverage of query (53.1 bits)

PS417_07255 Deoxyribonolactonase from Pseudomonas simiae WCS417
PS417_07255 / A0A1N7TX40 2-deoxy-ribono-1,5-lactonase from Pseudomonas simiae (see paper)
    25% identity, 88% coverage of query (53.1 bits)

SGL_PSEPU / P0DOV6 6-deoxy-6-sulfogluconolactonase; 6-deoxy-6-sulfogluconolactone lactonase; SGL lactonase; EC 3.1.1.99 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    27% identity, 83% coverage of query (52.4 bits)

5d9bA / Q95YI4 Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
    24% identity, 83% coverage of query (48.9 bits)

5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement)
    24% identity, 83% coverage of query (48.9 bits)

SMc00883 L-arabinolactonase/D-galactonolactonase (EC 3.1.1.15; EC 3.1.1.25) from Sinorhizobium meliloti 1021
GALAB_RHIME / Q92RN9 Putative sugar lactone lactonase; EC 3.1.1.- from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
    23% identity, 83% coverage of query (47.4 bits)

HSERO_RS05225 L-arabinolactonase (EC 3.1.1.15) from Herbaspirillum seropedicae SmR1
    25% identity, 83% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory