Searching for up to 100 curated homologs for HSERO_RS21095 FitnessBrowser__HerbieS:HSERO_RS21095 (336 a.a.)
Found high-coverage hits (≥70%) to 68 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CAPD_RICPR / Q9ZDJ5 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Rickettsia prowazekii (strain Madrid E) (see paper)
68% identity, 99% coverage of query (492 bits)
V5RBP5 UDP-glucose 4-epimerase (EC 5.1.3.2) from Acinetobacter baumannii (see paper)
68% identity, 98% coverage of query (475 bits)
wbjB / Q9KID0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see 2 papers)
68% identity, 99% coverage of query (472 bits)
A0A0H3JPH0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Staphylococcus aureus (see paper)
64% identity, 100% coverage of query (469 bits)
3w1vA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with inihibitor (see paper)
64% identity, 99% coverage of query (466 bits)
4g5hA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product
64% identity, 99% coverage of query (466 bits)
wbvB / Q8L348 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Vibrio cholerae O37 (see 3 papers)
65% identity, 99% coverage of query (455 bits)
4j2oC / P37362 Crystal structure of NADP-bound wbjb from a. Baumannii community strain d1279779 (see paper)
65% identity, 99% coverage of query (448 bits)
3vvcA Crystal structure of capsular polysaccharide synthesizing enzyme cape , k126e, in apo form
61% identity, 99% coverage of query (436 bits)
3vvbA / A0A0H3JPH0 Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form (see paper)
53% identity, 99% coverage of query (350 bits)
BC_3750 / Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.135) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see 5 papers)
Q81A42 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Bacillus cereus (see 2 papers)
41% identity, 98% coverage of query (245 bits)
pseB / O25511 UDP-N-acetylglucosamine 4,6-dehydratase subunit (EC 4.2.1.115) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 4 papers)
PSEB_HELPY / O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see 3 papers)
40% identity, 94% coverage of query (238 bits)
2gn4A / O25511 Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADPH and udp-glcnac (see paper)
40% identity, 94% coverage of query (238 bits)
2gn8A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp
40% identity, 94% coverage of query (238 bits)
2gnaA Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-gal
40% identity, 94% coverage of query (238 bits)
2gn9A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glc
40% identity, 94% coverage of query (238 bits)
2gn6A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glcnac
40% identity, 94% coverage of query (238 bits)
PSEB_CAMJE / Q0P8W4 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
43% identity, 90% coverage of query (237 bits)
Q6VYQ6 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
40% identity, 96% coverage of query (236 bits)
PSEB_CAMJJ / Q5QKR8 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) (see 2 papers)
44% identity, 84% coverage of query (235 bits)
Q6VYQ5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Helicobacter pylori (see paper)
39% identity, 96% coverage of query (234 bits)
6bwcC X-ray structure of pen from bacillus thuringiensis (see paper)
39% identity, 84% coverage of query (223 bits)
G5CSR9 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Megavirus chiliensis (see paper)
34% identity, 83% coverage of query (178 bits)
4tqgA / G5CSR9 Crystal structure of megavirus udp-glcnac 4,6-dehydratase, 5-epimerase mg534 (see paper)
33% identity, 83% coverage of query (160 bits)
EPSC_BACSU / P71052 Probable polysaccharide biosynthesis protein EpsC from Bacillus subtilis (strain 168) (see paper)
36% identity, 80% coverage of query (159 bits)
P72145 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see paper)
34% identity, 77% coverage of query (155 bits)
wbpM / Q9KIC5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Pseudomonas aeruginosa (see 6 papers)
34% identity, 77% coverage of query (154 bits)
wbiI / GI|3135688 putative epimerase/dehydratase WbiI from Burkholderia pseudomallei (see paper)
37% identity, 80% coverage of query (150 bits)
cpsE polysaccharide capsule synthesis protein CpsE from Streptococcus iniae (see paper)
35% identity, 81% coverage of query (150 bits)
RfbU / CAA69127.1 mannosyl-transferase from Vibrio cholerae (see paper)
33% identity, 95% coverage of query (150 bits)
wbgZ / Q9F736 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Shigella sonnei (see paper)
32% identity, 95% coverage of query (148 bits)
5bjuA / O86159 X-ray structure of the pglf dehydratase from campylobacter jejuni in complex with udp and NAD(h) (see paper)
34% identity, 81% coverage of query (142 bits)
pglF / Q0P9D4 UDP-N-acetylglucosamine C-6 dehydratase (EC 4.2.1.135) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
PGLF_CAMJE / Q0P9D4 UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase; UDP-GlcNAc C6 dehydratase; Protein glycosylation pathway protein F; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining); EC 4.2.1.135 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
34% identity, 80% coverage of query (140 bits)
5bjvA X-ray structure of the pglf udp-n-acetylglucosamine 4,6-dehydratase from campylobacterjejuni, d396n/k397a variant in complex with udp-n- acrtylglucosamine
33% identity, 81% coverage of query (137 bits)
wbkD / Q2YMM0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Brucella abortus (strain 2308) (see 2 papers)
30% identity, 83% coverage of query (132 bits)
Build an alignment for HSERO_RS21095 and 35 homologs with ≥ 30% identity
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3pvzA / Q5E8L1 Udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri
28% identity, 74% coverage of query (82.8 bits)
3pvzB / Q5E8L1 Udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri
27% identity, 71% coverage of query (72.4 bits)
graE / AAA99939.1 dTDP-glucose dehydratase from Streptomyces violaceoruber (see paper)
24% identity, 82% coverage of query (68.2 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
26% identity, 71% coverage of query (66.6 bits)
N0A8N8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
23% identity, 73% coverage of query (65.9 bits)
Q9ZV36 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
24% identity, 73% coverage of query (65.1 bits)
N0A414 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
24% identity, 73% coverage of query (65.1 bits)
Q9AV98 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Pisum sativum (see paper)
uxs1 / BAB40967.1 UDP-D-glucuronate carboxy-lyase from Pisum sativum (see paper)
23% identity, 73% coverage of query (63.9 bits)
UXS3 / Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 2 papers)
UXS3_ARATH / Q9FIE8 UDP-glucuronic acid decarboxylase 3; UDP-XYL synthase 3; UDP-glucuronate decarboxylase 3; UGD; UXS-3; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
23% identity, 73% coverage of query (63.2 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
24% identity, 76% coverage of query (62.4 bits)
Q9SN95 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
23% identity, 73% coverage of query (62.0 bits)
UDPGlcADCX1 / Q6IVK5 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Nicotiana tabacum (see paper)
23% identity, 73% coverage of query (62.0 bits)
N0A422 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
24% identity, 73% coverage of query (61.2 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
26% identity, 76% coverage of query (60.8 bits)
desIV / Q9ZGH3 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces venezuelae (see paper)
26% identity, 76% coverage of query (60.5 bits)
tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
25% identity, 80% coverage of query (59.7 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
26% identity, 76% coverage of query (59.3 bits)
Q8W3J0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-3 / BAB84334.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
23% identity, 72% coverage of query (58.2 bits)
A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
26% identity, 71% coverage of query (58.2 bits)
jadT / Q939Q5 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
26% identity, 78% coverage of query (57.8 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
26% identity, 71% coverage of query (55.8 bits)
2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
22% identity, 72% coverage of query (54.3 bits)
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
25% identity, 75% coverage of query (53.9 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
25% identity, 75% coverage of query (53.9 bits)
UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
22% identity, 74% coverage of query (53.9 bits)
4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
23% identity, 72% coverage of query (52.0 bits)
UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
22% identity, 74% coverage of query (51.6 bits)
2pzmA / O87988 Crystal structure of the bordetella bronchiseptica enzyme wbmg in complex with NAD and udp (see paper)
23% identity, 75% coverage of query (51.2 bits)
RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
23% identity, 71% coverage of query (50.8 bits)
4lk3C Crystal structure of human udp-xylose synthase r236a substitution
22% identity, 72% coverage of query (50.4 bits)
RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
21% identity, 71% coverage of query (49.3 bits)
8fenA Panicum vigratum dihydroflavonol 4-reductase complexed with NADP and dhq
25% identity, 70% coverage of query (48.5 bits)
8femA / A0A8T0SQV2 Panicum vigratum dihydroflavonol 4-reductase complexed with NADP (see paper)
25% identity, 70% coverage of query (48.5 bits)
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Lawrence Berkeley National Laboratory