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Searching for up to 100 curated homologs for HSERO_RS22735 FitnessBrowser__HerbieS:HSERO_RS22735 (420 a.a.)

Found high-coverage hits (≥70%) to 10 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMc02873 N-Acetyl-D-glucosamine ABC transport system, periplasmic substrate-binding component from Sinorhizobium meliloti 1021
    55% identity, 98% coverage of query (476 bits)

PGA1_c27930 N-Acetyl-D-glucosamine ABC transport system, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    54% identity, 95% coverage of query (467 bits)

Build an alignment

Build an alignment for HSERO_RS22735 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.1.24 / Q72KX2 Glucose-binding protein aka TT_C0328, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    27% identity, 78% coverage of query (83.6 bits)

MSME_STRMU / Q00749 Multiple sugar-binding protein from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see paper)
TC 3.A.1.1.28 / Q00749 MsmE aka SMU.878, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
    25% identity, 77% coverage of query (78.6 bits)

2b3bA / Q72KX2 Thermus thermophilus glucose/galactose binding protein with bound glucose (see paper)
    26% identity, 71% coverage of query (68.6 bits)

2b3fA Thermus thermophilus glucose/galactose binding protein bound with galactose
    26% identity, 71% coverage of query (68.6 bits)

2b3bC Thermus thermophilus glucose/galactose binding protein with bound glucose
    26% identity, 71% coverage of query (68.6 bits)

6preA / A0A0H2URJ7 Sbp rafe in complex with verbascose (see paper)
    24% identity, 72% coverage of query (58.9 bits)

2i58A Crystal structure of rafe from streptococcus pneumoniae complexed with raffinose
    24% identity, 72% coverage of query (57.0 bits)

4g68A / J9PBT4 Biochemical and structural insights into xylan utilization by the thermophilic bacteriumcaldanaerobius polysaccharolyticus (see paper)
    22% identity, 74% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory