Searching for up to 100 curated homologs for HSERO_RS23010 FitnessBrowser__HerbieS:HSERO_RS23010 (408 a.a.)
Found high-coverage hits (≥70%) to 40 curated proteins.
Removed hits that are identical to the query, leaving 39
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ExuT / b3093 hexuronate transporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
exuT / P0AA78 hexuronate transporter from Escherichia coli (strain K12) (see 3 papers)
EXUT_ECOLI / P0AA78 Hexuronate transporter; Aldohexuronate transport system from Escherichia coli (strain K12) (see 5 papers)
56% identity, 99% coverage of query (477 bits)
TC 2.A.1.14.2 / P0AA78 Hexuronate (glucuronate; galacturonate) porter, ExuT (Nemoz et al. 1976). It also transports D-glucose (HJ Kim et al., Front. Microbiol., 23 January 2020) from Escherichia coli (see 3 papers)
56% identity, 99% coverage of query (476 bits)
EXUT_DICCH / P94774 Galacturonate transporter from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
TC 2.A.1.14.41 / P94774 The Aldohexuronate (glucuronate, galacturonate) uptake porter from Dickeya chrysanthemi
exuT / AAB70881.1 exuT from Dickeya chrysanthemi (see paper)
57% identity, 78% coverage of query (393 bits)
Pf1N1B4_5129 D-galacturonate transporter ExuT from Pseudomonas fluorescens FW300-N1B4
30% identity, 100% coverage of query (165 bits)
Build an alignment for HSERO_RS23010 and 4 homologs with ≥ 30% identity
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YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
26% identity, 96% coverage of query (155 bits)
6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
26% identity, 96% coverage of query (154 bits)
CA265_RS19855 D-galacturonate transporter ExuT from Pedobacter sp. GW460-11-11-14-LB5
27% identity, 85% coverage of query (147 bits)
LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
29% identity, 72% coverage of query (142 bits)
SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
28% identity, 92% coverage of query (141 bits)
BT4105 D-galacturonate transporter ExuT from Bacteroides thetaiotaomicron VPI-5482
28% identity, 86% coverage of query (135 bits)
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
26% identity, 96% coverage of query (134 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
27% identity, 90% coverage of query (131 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
27% identity, 90% coverage of query (131 bits)
GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
27% identity, 92% coverage of query (129 bits)
PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
25% identity, 97% coverage of query (128 bits)
AO356_28540 D-mannose transporter from Pseudomonas fluorescens FW300-N2C3
28% identity, 89% coverage of query (118 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
25% identity, 92% coverage of query (114 bits)
ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
26% identity, 97% coverage of query (108 bits)
S17A5_SHEEP / Q9MZD1 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein SP55; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Ovis aries (Sheep) (see paper)
28% identity, 74% coverage of query (105 bits)
S17A5_HUMAN / Q9NRA2 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein HP59; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Homo sapiens (Human) (see 10 papers)
TC 2.A.1.14.10 / Q9NRA2 Lysosomal sialate transporter (Salla disease and infantile sialate storage disease protein (Morin et al., 2004)). Also transports glucuronic acid and aspartate. Structure-function studies have identify crucial residues and substrate-induced conformational changes (Courville et al., 2010). Also called SLC17A5. The substrate binding pocket has been identified based on modeling studies (see 8 papers)
27% identity, 75% coverage of query (103 bits)
ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
24% identity, 97% coverage of query (94.4 bits)
TC 2.A.1.4.2 / P12681 P-glycerate:Pi antiporter, Pgt from Salmonella typhimurium (see 2 papers)
24% identity, 94% coverage of query (93.2 bits)
ANTR4_ARATH / Q66GI9 Probable anion transporter 4, chloroplastic; Phosphate transporter PHT4;3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
26% identity, 85% coverage of query (82.4 bits)
BWI76_RS23715 2-deoxy-D-ribonate transporter 1 from Klebsiella michiganensis M5al
22% identity, 92% coverage of query (82.0 bits)
ANTR3_ARATH / Q7XJR2 Probable anion transporter 3, chloroplastic; Phosphate transporter PHT4;2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q7XJR2 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see paper)
22% identity, 97% coverage of query (80.1 bits)
NPT1_MOUSE / Q61983 Sodium-dependent phosphate transport protein 1; Na(+)/PI cotransporter 1; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protein 1; Sodium/phosphate cotransporter 1; Solute carrier family 17 member 1 from Mus musculus (Mouse) (see 2 papers)
24% identity, 75% coverage of query (73.9 bits)
NPT1_HUMAN / Q14916 Sodium-dependent phosphate transport protein 1; Na(+)/PI cotransporter 1; Na/Pi-4; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protein 1; Sodium/phosphate cotransporter 1; Solute carrier family 17 member 1 from Homo sapiens (Human) (see 3 papers)
TC 2.A.1.14.27 / Q14916 Voltage-driven Na+:phosphate cotransporter; solute carrier family 17, member 1 from Homo sapiens (see 7 papers)
26% identity, 86% coverage of query (71.6 bits)
S17A4_MOUSE / Q5NCM1 Probable small intestine urate exporter; Solute carrier family 17 member 4 from Mus musculus (Mouse) (see paper)
25% identity, 85% coverage of query (70.9 bits)
ANTR6_ARATH / Q3E9A0 Probable anion transporter 6, chloroplastic; Phosphate transporter PHT4;5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 99% coverage of query (70.9 bits)
NPT1_RABIT / Q28722 Sodium-dependent phosphate transport protein 1; NAPI-1; Na(+)/PI cotransporter 1; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protein 1; Sodium/phosphate cotransporter 1; Solute carrier family 17 member 1 from Oryctolagus cuniculus (Rabbit) (see paper)
24% identity, 86% coverage of query (70.1 bits)
BWI76_RS23725 2-deoxy-D-ribonate transporter 2 from Klebsiella michiganensis M5al
21% identity, 95% coverage of query (69.3 bits)
H281DRAFT_00642 2-deoxy-D-ribonate transporter from Paraburkholderia bryophila 376MFSha3.1
24% identity, 98% coverage of query (67.8 bits)
Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
26% identity, 93% coverage of query (64.7 bits)
TC 2.A.1.14.8 / Q9RPP3 Phthalate porter from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
22% identity, 78% coverage of query (64.7 bits)
A0A0H3JLD7 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Staphylococcus aureus (see paper)
22% identity, 93% coverage of query (64.3 bits)
UhpC / b3667 inner membrane protein sensing glucose-6-phosphate from Escherichia coli K-12 substr. MG1655 (see 4 papers)
UHPC_ECOLI / P09836 Membrane sensor protein UhpC from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.1.4.4 / P09836 Hexose-P:Pi antiporter regulatory protein; senses external glucose-6-P and transports it with high affinity and low efficiency from Escherichia coli (see 7 papers)
uhpC regulatory protein UhpC from Escherichia coli K12 (see 7 papers)
uhpC / ECOCYC|GLU-UHPC membrane protein regulates uhpT expression from Escherichia coli K12 (see 2 papers)
24% identity, 86% coverage of query (62.8 bits)
ANTR5_ARATH / Q9FKV1 Probable anion transporter 5; Phosphate transporter PHT4;6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
21% identity, 73% coverage of query (59.7 bits)
G6PT3_HUMAN / Q8TED4 Glucose-6-phosphate exchanger SLC37A2; Solute carrier family 37 member 2 from Homo sapiens (Human) (see paper)
TC 2.A.1.4.8 / Q8TED4 solute carrier family 37 (putative glycerol-3-phosphate transporter), member 2. Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane from Homo sapiens (see 3 papers)
23% identity, 72% coverage of query (59.3 bits)
UhpT / b3666 hexose-6-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 12 papers)
uhpT / P0AGC0 hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 14 papers)
UHPT_ECOLI / P0AGC0 Hexose-6-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 11 papers)
23% identity, 88% coverage of query (49.7 bits)
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Lawrence Berkeley National Laboratory