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Searching for up to 100 curated homologs for HSERO_RS23535 HSERO_RS23535 acyl-CoA synthetase (546 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9HWI3 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Pseudomonas aeruginosa (see paper)
    61% identity, 98% coverage of query (674 bits)

Q5LVM3 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Ruegeria pomeroyi (see paper)
    61% identity, 98% coverage of query (667 bits)

Q4FP19 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Candidatus Pelagibacter ubique (see paper)
    50% identity, 99% coverage of query (588 bits)

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    52% identity, 98% coverage of query (566 bits)

CCL3_HUMLU / M4IS88 Acetate--CoA ligase CCL3; HlCCL3; 2-methylbutanoate--CoA ligase CCL4; 2-methylpropanoate--CoA ligase CCL4; Butanoate--CoA ligase CCL3; Hexanoate--CoA ligase CCL3; Isovalerate--CoA ligase CCL3; Pentanoate--CoA ligase CCL3; Propionate--CoA ligase CCL3; EC 6.2.1.1; EC 6.2.1.-; EC 6.2.1.17 from Humulus lupulus (European hop) (see paper)
    51% identity, 99% coverage of query (565 bits)

AAE1_ARATH / F4HUK6 Butanoate--CoA ligase AAE1; 4-methylpentanoate--CoA ligase AAE2; AMP-binding protein 1; AtAMPBP1; Acyl-activating enzyme 1, peroxisomal; Hexanoate--CoA ligase CCL3; Pentanoate--CoA ligase CCL3; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    49% identity, 98% coverage of query (541 bits)

CNL / J9ZU73 cinnamate:CoA ligase (EC 6.2.1.12) from Hypericum calycinum (see paper)
    51% identity, 98% coverage of query (537 bits)

AAE2_ARATH / Q9SEY5 Isovalerate--CoA ligase AAE2; 3-methylpentanoate--CoA ligase AAE2; 4-methylpentanoate--CoA ligase AAE2; AMP-binding protein 2; AtAMPBP2; Acyl-activating enzyme 2; Butanoate--CoA ligase AAE2; Hexanoate--CoA ligase AAE2; Pentanoate--CoA ligase AAE2; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    49% identity, 97% coverage of query (532 bits)

CCL4 / M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus (see paper)
CCL4_HUMLU / M4IQQ5 2-methylpropanoate--CoA ligase CCL4; HlCCL4; 2-methylbutanoate--CoA ligase CCL4; Butanoate--CoA ligase CCL3; Propionate--CoA ligase CCL3; EC 6.2.1.-; EC 6.2.1.17 from Humulus lupulus (European hop) (see paper)
    50% identity, 96% coverage of query (528 bits)

lvaE / Q88J54 short chain acyl-CoA synthetase (EC 6.2.1.2) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    51% identity, 98% coverage of query (523 bits)

CCL2 / M4IRL4 isovalerate--CoA ligase (EC 6.2.1.1) from Humulus lupulus (see paper)
CCL2_HUMLU / M4IRL4 Isovalerate--CoA ligase CCL2; HlCCL2; 3-methylpentanoate--CoA ligase AAE2; 4-methylpentanoate--CoA ligase AAE2; Butanoate--CoA ligase CCL3; Hexanoate--CoA ligase CCL3; Pentanoate--CoA ligase CCL3; EC 6.2.1.- from Humulus lupulus (European hop) (see paper)
    48% identity, 97% coverage of query (514 bits)

CNL / I3PB36 cinnamate:CoA ligase (EC 6.2.1.12) from Petunia hybrida (see 3 papers)
CNL_PETHY / I3PB36 Trans-cinnamate:CoA ligase, peroxisomal; Cinnamic acid:CoA ligase; Ph-CNL; PhCNL; (E)-caffeate:CoA ligase CNL; 4-coumarate:CoA ligase CNL; Protein ACYL-ACTIVATING ENZYME; PhAAE; EC 6.2.1.-; EC 6.2.1.12 from Petunia hybrida (Petunia) (see 2 papers)
    47% identity, 98% coverage of query (511 bits)

AAE5_ARATH / Q9FFE6 Probable acyl-activating enzyme 5, peroxisomal; AMP-binding protein 5; AtAMPBP5; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    48% identity, 97% coverage of query (504 bits)

AAE6_ARATH / Q9FFE9 Probable acyl-activating enzyme 6; AMP-binding protein 6; AtAMPBP6; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    48% identity, 97% coverage of query (504 bits)

AAE11_ARATH / Q9C8D4 Butyrate--CoA ligase AAE11, peroxisomal; Acyl-activating enzyme 11; Butyryl-CoA synthetase; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    47% identity, 97% coverage of query (491 bits)

AAE12_ARATH / Q9SS00 Probable acyl-activating enzyme 12, peroxisomal; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    46% identity, 98% coverage of query (486 bits)

AT1G65880 / Q9SS01 benzoate-CoA ligase (EC 6.2.1.25) from Arabidopsis thaliana (see paper)
AAE20_ARATH / Q9SS01 Benzoate--CoA ligase, peroxisomal; Acyl-activating enzyme 20; Protein BENZOYLOXYGLUCOSINOLATE 1; EC 6.2.1.25 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    47% identity, 98% coverage of query (483 bits)

AAE4_ARATH / O80658 Probable acyl-activating enzyme 4; AMP-binding protein 4; AtAMPBP4; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    45% identity, 97% coverage of query (483 bits)

AAE8_ARATH / Q9LQS1 Probable acyl-activating enzyme 8; AMP-binding protein 8; AtAMPBP8; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    47% identity, 98% coverage of query (478 bits)

AEE9_ARATH / Q9LPK6 Probable acyl-activating enzyme 9; AMP-binding protein 9; AtAMPBP9; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    45% identity, 97% coverage of query (464 bits)

AEE10_ARATH / Q9LPK7 Probable acyl-activating enzyme 10; AMP-binding protein 10; AtAMPBP10; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    44% identity, 97% coverage of query (460 bits)

HBCL2_METS5 / A4YDR9 4-hydroxybutyrate--CoA ligase 2; Acetate--CoA ligase; Butyrate--CoA ligase; Propionate--CoA ligase; acyl-activating enzyme; EC 6.2.1.40; EC 6.2.1.1; EC 6.2.1.2; EC 6.2.1.17 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
A4YDR9 4-hydroxybutyrate-CoA ligase (AMP-forming) (EC 6.2.1.40) from Metallosphaera sedula (see paper)
    39% identity, 98% coverage of query (395 bits)

LCFCS_THET8 / Q5SKN9 Long-chain-fatty-acid--CoA ligase; Long-chain fatty acyl-CoA synthetase; LC-FACS; EC 6.2.1.3 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    35% identity, 95% coverage of query (270 bits)

norE / B4ER89 4-nitrobenzoate–CoA ligase from Streptomyces orinoci (see 2 papers)
    34% identity, 95% coverage of query (256 bits)

1v26B / Q5SKN9 Crystal structure of tt0168 from thermus thermophilus hb8 (see paper)
    34% identity, 93% coverage of query (243 bits)

1v25A Crystal structure of tt0168 from thermus thermophilus hb8
    35% identity, 85% coverage of query (240 bits)

alkK / Q00594 medium-chain acyl-CoA synthetase (EC 6.2.1.2) from Pseudomonas oleovorans (see 2 papers)
ALKK_PSEOL / Q00594 Medium-chain-fatty-acid--CoA ligase; Medium-chain acyl-CoA synthetase; EC 6.2.1.2 from Pseudomonas oleovorans (see paper)
alkK / CAB54055.1 acyl-CoA synthetase from Pseudomonas putida (see 6 papers)
    31% identity, 92% coverage of query (237 bits)

Q2SWN7 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Burkholderia thailandensis (see paper)
    34% identity, 90% coverage of query (232 bits)

8i3iA Acyl-acp synthetase structure bound to amp-pnp
    31% identity, 96% coverage of query (230 bits)

8i22A / Q00IB3 Acyl-acp synthetase structure bound to pimelic acid monoethyl ester
    30% identity, 96% coverage of query (228 bits)

8i6mA Acyl-acp synthetase structure bound to amp-c18:1
    30% identity, 96% coverage of query (228 bits)

8i51A Acyl-acp synthetase structure bound to amp-mc7
    30% identity, 96% coverage of query (228 bits)

8i8dA Acyl-acp synthetase structure bound to mc7-acp
    30% identity, 96% coverage of query (228 bits)

8i8eA Acyl-acp synthetase structure bound to c18:1-acp
    30% identity, 96% coverage of query (228 bits)

8i49A Acyl-acp synthetase structure bound to atp
    30% identity, 96% coverage of query (228 bits)

DMDB_RUELI / P0DX84 3-methylmercaptopropionyl-CoA ligase; MMPA-CoA ligase; EC 6.2.1.44 from Ruegeria lacuscaerulensis (strain DSM 11314 / KCTC 2953 / ITI-1157) (Silicibacter lacuscaerulensis) (see paper)
    31% identity, 94% coverage of query (223 bits)

dmdB / Q5LRT0 3-methylmercaptopropionyl-CoA ligase (EC 6.2.1.44) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (see paper)
DMDB_RUEPO / Q5LRT0 3-methylmercaptopropionyl-CoA ligase; MMPA-CoA ligase; Acyl-CoA ligase; EC 6.2.1.44 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see 2 papers)
Q5LRT0 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Ruegeria pomeroyi (see 2 papers)
    31% identity, 92% coverage of query (223 bits)

6ijbB Structure of 3-methylmercaptopropionate coa ligase mutant k523a in complex with amp and mmpa (see paper)
    31% identity, 94% coverage of query (221 bits)

FCS_AMYSP / Q9EY88 Feruloyl-CoA synthase; Feruloyl coenzyme A synthetase; Feruloyl-CoA synthetase; EC 6.2.1.34 from Amycolatopsis sp. (see paper)
FCS_STRSQ / S5M744 Feruloyl-CoA synthase; Feruloyl coenzyme A synthetase; Feruloyl-CoA synthetase; EC 6.2.1.34 from Streptomyces sp. (see paper)
fcs / CAC18323.1 feruloyl-CoA synthetase from Amycolatopsis sp. HR167 (see paper)
    33% identity, 92% coverage of query (220 bits)

FAC13_MYCTU / P9WQ37 Long-chain-fatty-acid--CoA ligase FadD13; Fatty acyl-CoA ligase; FACL; FACL13; Fatty acyl-CoA synthetase; ACS; FACS; Very-long-chain fatty-acyl-CoA synthetase; ACSVL; EC 6.2.1.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 7 papers)
    32% identity, 91% coverage of query (213 bits)

6ihkB Structure of mmpa coa ligase in complex with adp
    30% identity, 94% coverage of query (212 bits)

aliA / O07454 AliA from Rhodopseudomonas palustris (see 2 papers)
    32% identity, 89% coverage of query (206 bits)

3r44A / P9WQ37 Mycobacterium tuberculosis fatty acyl coa synthetase (see paper)
    31% identity, 91% coverage of query (202 bits)

ORF35 / Q52V67 acyl-CoA ligase from Streptomyces aizunensis (see paper)
    33% identity, 94% coverage of query (197 bits)

geoC / W8X9R1 perillate-CoA ligase from Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen) (see 2 papers)
    31% identity, 93% coverage of query (195 bits)

Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
    31% identity, 95% coverage of query (192 bits)

Build an alignment

Build an alignment for HSERO_RS23535 and 46 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

Q81K97 O-succinylbenzoate-CoA ligase (EC 6.2.1.26) from Bacillus anthracis (see paper)
    28% identity, 94% coverage of query (187 bits)

fadD3 / Q0S7V5 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase (EC 6.2.1.41) from Rhodococcus jostii (strain RHA1) (see 3 papers)
FAD3_RHOJR / Q0S7V5 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase; HIP:CoA ligase; EC 6.2.1.41 from Rhodococcus jostii (strain RHA1) (see paper)
    30% identity, 95% coverage of query (187 bits)

ACSF2_HUMAN / Q96CM8 Medium-chain acyl-CoA ligase ACSF2, mitochondrial; EC 6.2.1.2 from Homo sapiens (Human) (see 2 papers)
    30% identity, 92% coverage of query (186 bits)

IAAB_AROAE / Q5P603 Indoleacetate--CoA ligase; EC 6.2.1.75 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) (see paper)
    29% identity, 94% coverage of query (186 bits)

INLPC_STRC4 / P0DX14 Fatty acid--[acyl-carrier-protein] ligase ScoC; EC 6.2.1.-; EC 6.2.1.47 from Streptomyces coeruleorubidus (see 2 papers)
    31% identity, 92% coverage of query (186 bits)

FADD3_COMTE / Q7WSH3 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase; HIP:CoA ligase; EC 6.2.1.41 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
    29% identity, 97% coverage of query (185 bits)

LCFB_BACSU / O07610 Long-chain-fatty-acid--CoA ligase; Long-chain acyl-CoA synthetase; EC 6.2.1.3 from Bacillus subtilis (strain 168) (see paper)
    30% identity, 90% coverage of query (182 bits)

5x8fB / P23971 Ternary complex structure of a double mutant i454ra456k of o- succinylbenzoate coa synthetase (mene) from bacillus subtilis bound with amp and its product analogue osb-ncoa at 1.76 angstrom (see paper)
    27% identity, 95% coverage of query (181 bits)

menE / P23971 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) from Bacillus subtilis (strain 168) (see 4 papers)
P23971 O-succinylbenzoate-CoA ligase (EC 6.2.1.26) from Bacillus subtilis (see paper)
    27% identity, 95% coverage of query (181 bits)

5gtdA O-succinylbenzoate coa synthetase (mene) from bacillus subtilis in complex with the acyl-adenylate intermediate osb-amp
    27% identity, 95% coverage of query (181 bits)

4CL3_ORYSJ / Q6ETN3 4-coumarate--CoA ligase 3; 4CL 3; Os4CL3; (E)-ferulate--CoA ligase; 4-coumaroyl-CoA synthase 3; EC 6.2.1.12; EC 6.2.1.34 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q6ETN3 4-coumarate-CoA ligase (EC 6.2.1.12) from Oryza sativa (see 2 papers)
    30% identity, 94% coverage of query (178 bits)

antF / A3KI30 anthranilate:acyl-carrier protein ligase from Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) (see paper)
    30% identity, 92% coverage of query (174 bits)

4CL1 / A0A4Y5UJ50 4-coumarate:CoA ligase (EC 6.2.1.12; EC 6.2.1.34) from Avena sativa (see 2 papers)
    30% identity, 89% coverage of query (174 bits)

SauT / Q0K844 sulfoacetate-CoA ligase (AMP-forming) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
SAUT_CUPNH / Q0K844 Sulfoacetate--CoA ligase; EC 6.2.1.- from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
    31% identity, 86% coverage of query (174 bits)

B3TJI5 4-coumarate-CoA ligase (EC 6.2.1.12) from Ruta graveolens (see paper)
    28% identity, 90% coverage of query (173 bits)

4CL4_ORYSJ / Q67W82 4-coumarate--CoA ligase 4; 4CL 4; Os4CL4; (E)-ferulate--CoA ligase; 4-coumaroyl-CoA synthase 4; Protein RESISTANCE TO ALUMINUM 1; EC 6.2.1.12; EC 6.2.1.34 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
Q67W82 4-coumarate-CoA ligase (EC 6.2.1.12) from Oryza sativa (see 2 papers)
    30% identity, 92% coverage of query (172 bits)

4CL2 / Q9S725 4-coumarate coenzyme A ligase 2 (EC 6.2.1.12) from Arabidopsis thaliana (see 2 papers)
4CL2_ARATH / Q9S725 4-coumarate--CoA ligase 2; 4CL 2; 4-coumarate--CoA ligase isoform 2; At4CL2; 4-coumaroyl-CoA synthase 2; Caffeate--CoA ligase; EC 6.2.1.12; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9S725 4-coumarate-CoA ligase (EC 6.2.1.12) from Arabidopsis thaliana (see 3 papers)
    27% identity, 95% coverage of query (171 bits)

5busA O-succinylbenzoate coenzyme a synthetase (mene) from bacillus subtilis, in complex with amp
    26% identity, 95% coverage of query (169 bits)

5burA O-succinylbenzoate coenzyme a synthetase (mene) from bacillus subtilis, in complex with atp and magnesium ion
    27% identity, 94% coverage of query (169 bits)

7tz4A / Q9HWG3 Salicylate adenylate pchd from pseudomonas aeruginosa containing 4- cyanosalicyl-ams (see paper)
    29% identity, 95% coverage of query (162 bits)

SIDI_ASPFU / Q4WR83 Acyl-CoA ligase sidI; Siderophore biosynthesis protein I; EC 6.2.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 6 papers)
    27% identity, 88% coverage of query (161 bits)

4wv3B / F3Y661 Crystal structure of the anthranilate coa ligase auaeii in complex with anthranoyl-amp (see paper)
    29% identity, 96% coverage of query (160 bits)

7tybA Salicylate adenylate pchd from pseudomonas aeruginosa containing salicyl-ams
    29% identity, 95% coverage of query (156 bits)

OldD / b1805 long-chain-fatty-acid—CoA ligase (EC 6.2.1.3) from Escherichia coli K-12 substr. MG1655 (see 14 papers)
fadD / P69451 long-chain-fatty-acid—CoA ligase (EC 6.2.1.3) from Escherichia coli (strain K12) (see 3 papers)
LCFA_ECOLI / P69451 Long-chain-fatty-acid--CoA ligase; Long-chain acyl-CoA synthetase; Acyl-CoA synthetase; EC 6.2.1.3 from Escherichia coli (strain K12) (see 2 papers)
TC 4.C.1.1.4 / P69451 Long chain fatty acyl CoA synthase (ligase), (EC 6.2.1.3) from Escherichia coli (see 6 papers)
fadD long-chain-fatty-acid--CoA ligase; EC 6.2.1.3 from Escherichia coli K12 (see 8 papers)
    27% identity, 96% coverage of query (152 bits)

5ie3A Crystal structure of a plant enzyme
    29% identity, 93% coverage of query (152 bits)

5ie2A / Q9SMT7 Crystal structure of a plant enzyme (see paper)
    29% identity, 93% coverage of query (152 bits)

AAE3 / Q9SMT7 oxalate--CoA ligase (EC 6.2.1.8) from Arabidopsis thaliana (see 4 papers)
4CLLA_ARATH / Q9SMT7 Oxalate--CoA ligase; 4-coumarate--CoA ligase isoform 8; At4CL8; 4-coumarate--CoA ligase-like 10; Acyl-activating enzyme 3; Adenosine monophosphate binding protein 3; AtMPBP3; Oxalyl-CoA synthetase; EC 6.2.1.8 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9SMT7 oxalate-CoA ligase (EC 6.2.1.8) from Arabidopsis thaliana (see 2 papers)
    29% identity, 93% coverage of query (152 bits)

6qjzA / A0A3G8GC37 Identificationand characterization of an oxalylfrom grass pea (lathyrus sativuscoa-synthetase l.) (see paper)
    28% identity, 92% coverage of query (148 bits)

4CL2_TOBAC / O24146 4-coumarate--CoA ligase 2; 4CL 2; Nt4CL-19; Nt4CL-2; 4-coumaroyl-CoA synthase 2; Caffeate--CoA ligase; Cinnamate--CoA ligase; Ferulate--CoA ligase; EC 6.2.1.12; EC 6.2.1.-; EC 6.2.1.34 from Nicotiana tabacum (Common tobacco) (see 2 papers)
O24146 4-coumarate-CoA ligase (EC 6.2.1.12) from Nicotiana tabacum (see 2 papers)
    26% identity, 93% coverage of query (146 bits)

5bsrA Crystal structure of 4-coumarate:coa ligase complexed with adenosine monophosphate and coenzyme a
    26% identity, 93% coverage of query (146 bits)

5bsvA Crystal structure of 4-coumarate:coa ligase complexed with feruloyl adenylate
    26% identity, 93% coverage of query (146 bits)

5bsuA Crystal structure of 4-coumarate:coa ligase complexed with caffeoyl adenylate
    26% identity, 93% coverage of query (146 bits)

5bstA Crystal structure of 4-coumarate:coa ligase complexed with coumaroyl adenylate
    26% identity, 93% coverage of query (146 bits)

5bsmA / O24146 Crystal structure of 4-coumarate:coa ligase complexed with magnesium and adenosine triphosphate (see paper)
    26% identity, 93% coverage of query (146 bits)

5buqB Unliganded form of o-succinylbenzoate coenzyme a synthetase (mene) from bacillus subtilis, solved at 1.98 angstroms
    25% identity, 95% coverage of query (145 bits)

O74976 Oxalate--CoA ligase; Oxalyl-CoA synthetase; Peroxisomal-coenzyme A synthetase; EC 6.2.1.8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    28% identity, 90% coverage of query (142 bits)

6k4cA Ancestral luciferase anclamp in complex with dlsa
    25% identity, 89% coverage of query (141 bits)

6k4dA Ancestral luciferase anclamp in complex with atp and d-luciferin (see paper)
    25% identity, 89% coverage of query (141 bits)

1md9A / P40871 Crystal structure of dhbe in complex with dhb and amp (see paper)
    28% identity, 97% coverage of query (141 bits)

3ni2A Crystal structures and enzymatic mechanisms of a populus tomentosa 4- coumarate:coa ligase
    28% identity, 89% coverage of query (140 bits)

3a9vA / Q941M3 Crystal structures and enzymatic mechanisms of a populus tomentosa 4- coumarate--coa ligase (see paper)
    28% identity, 89% coverage of query (140 bits)

dhbE / P40871 DhbE monomer (EC 6.2.1.71) from Bacillus subtilis (strain 168) (see paper)
DHBE_BACSU / P40871 2,3-dihydroxybenzoate-AMP ligase; Dihydroxybenzoic acid-activating enzyme; EC 6.2.1.71 from Bacillus subtilis (strain 168) (see paper)
    29% identity, 97% coverage of query (139 bits)

4CLL5_ARATH / Q84P21 Peroxisomal OPC-8:0-CoA ligase 1; 4-coumarate--CoA ligase isoform 9; At4CL9; 4-coumarate--CoA ligase-like 5; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
OPCL1 / ABJ98946.1 peroxisomal OPC-8:0 CoA ligase from Arabidopsis thaliana (see paper)
    25% identity, 98% coverage of query (139 bits)

5u95B Structure of the open conformation of 4-coumarate-coa ligase from nicotiana tabacum
    26% identity, 93% coverage of query (139 bits)

7kydA / Q9VCC6 Drosophila melanogaster long-chain fatty-acyl-coa synthetase cg6178 (see paper)
    26% identity, 95% coverage of query (137 bits)

5zrnA Inhibitor bound crystal structure of n-terminal domain of facl13 from mycobacterium tuberculosis
    29% identity, 73% coverage of query (135 bits)

4gxqA / Q13WK3,Q6ND88 Crystal structure of atp bound rpmatb-bxbclm chimera b1 (see paper)
    28% identity, 89% coverage of query (134 bits)

3dlpX / Q8GN86 4-chlorobenzoyl-coa ligase/synthetase, mutant d402p, bound to 4cb (see paper)
    28% identity, 94% coverage of query (130 bits)

ACSF3 / Q4G176 malonate—CoA ligase, mitochondrial (EC 6.2.1.76) from Homo sapiens (see 3 papers)
ACSF3_HUMAN / Q4G176 Malonate--CoA ligase ACSF3, mitochondrial; Acyl-CoA synthetase family member 3; EC 6.2.1.76 from Homo sapiens (Human) (see 3 papers)
    28% identity, 93% coverage of query (129 bits)

3cw9A 4-chlorobenzoyl-coa ligase/synthetase in the thioester-forming conformation, bound to 4-chlorophenacyl-coa
    28% identity, 94% coverage of query (129 bits)

6m2uA The crystal structure of benzoate coenzyme a ligase double mutant (h333a/i334a) in complex with 2-chloro-1,3-thiazole-5-carboxylate-amp
    28% identity, 92% coverage of query (128 bits)

6m2tA The crystal structure of benzoate coenzyme a ligase double mutant (h333a/i334a) in complex with 2-methyl-thiazole-5 carboxylate-amp
    28% identity, 92% coverage of query (128 bits)

5uptA Acyl-coa synthetase ptma2 from streptomyces platensis in complex with sbnp468 ligand
    26% identity, 90% coverage of query (128 bits)

5upsA / A0A0A0V031 Acyl-coa synthetase ptma2 from streptomyces platensis in complex with sbnp663 ligand (see paper)
    26% identity, 90% coverage of query (127 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory