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Searching for up to 100 curated homologs for IAI46_18455 (85 a.a.)

Found high-coverage hits (≥70%) to 34 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Hpr / b2415 phosphocarrier protein HPr from Escherichia coli K-12 substr. MG1655 (see 31 papers)
ptsH / P0AA04 phosphocarrier protein HPr from Escherichia coli (strain K12) (see 31 papers)
1j6tB / P0AA04 Complex of enzyme iiamtl and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
ptsH phosphocarrier protein HPr; EC 2.7.11.- from Escherichia coli K12 (see 19 papers)
    99% identity, 100% coverage of query (168 bits)

1pohA The 2.0 angstroms resolution structure of escherichia coli histidine- containing phosphocarrier protein hpr: a redetermination
    99% identity, 100% coverage of query (168 bits)

P0AA04 Phosphocarrier protein HPr; Histidine-containing protein from Escherichia coli (strain K12)
    99% identity, 100% coverage of query (168 bits)

CRH_BACSU / O06976 HPr-like protein Crh; Catabolite repression HPr from Bacillus subtilis (strain 168) (see 3 papers)
    47% identity, 98% coverage of query (77.8 bits)

ptsH / AAO61680.1 phosphocarrier protein HPr from Clostridium acetobutylicum (see paper)
    41% identity, 100% coverage of query (73.9 bits)

PS417_23035 D-trehalose PTS system, I, HPr, and IIA components from Pseudomonas simiae WCS417
    43% identity, 98% coverage of query (72.4 bits)

O69250 Phosphocarrier protein HPr; Histidine-containing protein from Priestia megaterium (Bacillus megaterium)
    42% identity, 98% coverage of query (71.2 bits)

AO353_15995 trehalose-specific PTS system, I, HPr, and IIA components from Pseudomonas fluorescens FW300-N2E3
    41% identity, 98% coverage of query (69.7 bits)

PTHP_LYSSH / Q84F84 Phosphocarrier protein HPr; Histidine-containing protein from Lysinibacillus sphaericus (Bacillus sphaericus) (see paper)
    42% identity, 99% coverage of query (66.6 bits)

PTFAH_HAEIN / P44715 Multiphosphoryl transfer protein; MTP; Diphosphoryl transfer protein; DTP; Phosphotransferase FPr protein; Pseudo-HPr from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
    48% identity, 89% coverage of query (65.9 bits)

ptsH / AAC45390.1 HPr from Lactobacillus sakei (see paper)
    40% identity, 95% coverage of query (64.7 bits)

P24366 Phosphocarrier protein HPr; Histidine-containing protein from Streptococcus salivarius
    41% identity, 95% coverage of query (64.7 bits)

PTHP_BACSU / P08877 Phosphocarrier protein HPr; Histidine-containing protein from Bacillus subtilis (strain 168) (see paper)
    37% identity, 95% coverage of query (64.3 bits)

Q9CJ83 Phosphocarrier protein HPr; Histidine-containing protein from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
    42% identity, 95% coverage of query (64.3 bits)

ptsH / AAA16213.1 phosphocarrier protein from Mycoplasma capricolum (see paper)
    37% identity, 89% coverage of query (60.1 bits)

PTFAX_XANCP / P45597 Multiphosphoryl transfer protein; MTP; Triphosphoryl transfer protein; TTP; EC 2.7.3.9 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    40% identity, 94% coverage of query (59.7 bits)

phbH / AAA21977.1 protein H from Cupriavidus necator (see paper)
    35% identity, 96% coverage of query (59.7 bits)

Q9WXK8 Phosphocarrier protein HPr; Histidine-containing protein from Streptococcus equinus (Streptococcus bovis)
    45% identity, 79% coverage of query (59.7 bits)

PTHP_BACTI / Q9F166 Phosphocarrier protein HPr from Bacillus thuringiensis subsp. israelensis (see 2 papers)
    37% identity, 79% coverage of query (55.8 bits)

P75061 Phosphocarrier protein HPr; Histidine-containing protein from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (Mycoplasmoides pneumoniae)
    37% identity, 87% coverage of query (55.1 bits)

PTFAH_SALTY / P17127 Multiphosphoryl transfer protein; MTP; Diphosphoryl transfer protein; DTP; Phosphotransferase FPr protein; Pseudo-HPr from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    37% identity, 86% coverage of query (53.1 bits)

DHAM_PROSM / P0DN88 PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM; Dihydroxyacetone kinase subunit M; EC 2.7.1.121 from Providencia stuartii (strain MRSN 2154) (see 2 papers)
    41% identity, 75% coverage of query (53.1 bits)

FruB / b2169 fructose-specific PTS multiphosphoryl transfer protein FruB from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FruB / P69811 fructose-specific PTS multiphosphoryl transfer protein FruB from Escherichia coli (strain K12) (see 2 papers)
PTFAH_ECOLI / P69811 Multiphosphoryl transfer protein; MTP; Diphosphoryl transfer protein; DTP; Phosphotransferase FPr protein; Pseudo-HPr from Escherichia coli (strain K12) (see paper)
TC 4.A.2.1.1 / P69811 PTFA aka FRUB aka FRUF aka FPR aka B2169, component of Fructose porter (FruAB) (fructose-1-P forming) from Escherichia coli (see 5 papers)
    36% identity, 88% coverage of query (53.1 bits)

PTFAH_VIBCH / Q9KM70 Multiphosphoryl transfer protein; MTP from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
    40% identity, 82% coverage of query (51.6 bits)

AZOBR_RS32325 Fructose PTS system (E-I, HPr, and E-IIA components) from Azospirillum brasilense Sp245
    41% identity, 87% coverage of query (49.3 bits)

O50515 Phosphocarrier protein HPr; Histidine-containing protein from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    31% identity, 98% coverage of query (49.3 bits)

TC 4.A.2.1.19 / M7QAG8 PTS system tagatose-specific IIA-TPr component, component of The tagatose-specific PTS transporter/kinase, TagIIA-TPr/TagIIB'BC (tagatose-1-P forming) from Klebsiella pneumoniae ATCC BAA-2146
    39% identity, 87% coverage of query (48.9 bits)

AO356_17540 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2C3
    35% identity, 92% coverage of query (48.5 bits)

Build an alignment

Build an alignment for IAI46_18455 and 28 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

PTHP_HALVD / D4GYE3 Phosphocarrier protein HPr from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    29% identity, 95% coverage of query (47.4 bits)

DHAM_PANAM / D4GL26 PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM; Dihydroxyacetone kinase subunit M; EC 2.7.1.121 from Pantoea ananatis (strain LMG 20103) (see 2 papers)
    33% identity, 92% coverage of query (47.0 bits)

ptsH / AAA86048.1 PTS HPr from Geobacillus stearothermophilus (see paper)
    31% identity, 75% coverage of query (45.8 bits)

TC 4.A.2.1.17 / Q9HY55 Phosphotransferase system transporter enzyme I, FruI, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    39% identity, 86% coverage of query (45.4 bits)

TC 4.A.2.1.26 / Q5V5X3 Phosphocarrier protein Hpr, component of Fructose-specific Enzyme I-HPr-Enzyme IIABC complex, all encoded within a single operon with genes in the order: ptsC (IIC), ptsA (IIA), ptsH (HPr), ptsI (Enzyme I) and ptsB (IIB) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
    26% identity, 94% coverage of query (43.1 bits)

DhaM / b1198 dihydroxyacetone kinase subunit M from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dhaM / P37349 dihydroxyacetone kinase subunit M from Escherichia coli (strain K12) (see 15 papers)
DHAM_ECOLI / P37349 PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM; Dihydroxyacetone kinase subunit M; EC 2.7.1.121 from Escherichia coli (strain K12) (see 3 papers)
P37349 phosphoenolpyruvate-glycerone phosphotransferase (subunit 1/3) (EC 2.7.1.121); glycerone kinase (EC 2.7.1.29) from Escherichia coli (see 4 papers)
    29% identity, 81% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory