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Searching for up to 100 curated homologs for N515DRAFT_0145 FitnessBrowser__Dyella79:N515DRAFT_0145 (453 a.a.)

Found high-coverage hits (≥70%) to 34 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_09645 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2C3
    52% identity, 98% coverage of query (428 bits)

HUTF_PSEAE / Q9HU77 Formimidoylglutamate deiminase; Formiminoglutamate deiminase; N-formimino-L-glutamate deiminase; N-formimino-L-glutamate iminohydrolase; EC 3.5.3.13 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HU77 formimidoylglutamate deiminase (EC 3.5.3.13); formimidoylglutamase (EC 3.5.3.8) from Pseudomonas aeruginosa (see paper)
    55% identity, 98% coverage of query (427 bits)

4rdvB / Q9HU77 The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-formimino-l-aspartate
    55% identity, 98% coverage of query (427 bits)

3mduA The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-guanidino-l-glutamate
    55% identity, 98% coverage of query (427 bits)

Pf6N2E2_3808 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E2
    52% identity, 98% coverage of query (426 bits)

hutF / Q4KJP1 formiminoglutamate deiminase subunit (EC 3.5.3.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    51% identity, 98% coverage of query (424 bits)

PfGW456L13_330 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens GW456-L13
    51% identity, 95% coverage of query (416 bits)

PS417_01705 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas simiae WCS417
    50% identity, 98% coverage of query (411 bits)

Pf1N1B4_1591 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N1B4
    51% identity, 95% coverage of query (411 bits)

AO353_12235 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E3
    51% identity, 98% coverage of query (410 bits)

SMc00673 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Sinorhizobium meliloti 1021
    51% identity, 99% coverage of query (388 bits)

Ac3H11_2549 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Acidovorax sp. GW101-3H11
    51% identity, 94% coverage of query (386 bits)

4f0lB / Q2YIL4 Crystal structure of amidohydrolase from brucella melitensis
    49% identity, 93% coverage of query (359 bits)

PGA1_c36360 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Phaeobacter inhibens BS107
    47% identity, 99% coverage of query (349 bits)

PA0142 / Q9I6Z0 8-oxoguanine deaminase monomer (EC 3.5.4.32) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
OXODE_PSEAE / Q9I6Z0 8-oxoguanine deaminase; EC 3.5.4.32 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6Z0 8-oxoguanine deaminase (EC 3.5.4.32) from Pseudomonas aeruginosa (see paper)
    30% identity, 89% coverage of query (95.9 bits)

Build an alignment

Build an alignment for N515DRAFT_0145 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

cyrH / B0LI34 CyrH from Cylindrospermopsis raciborskii AWT205 (see 2 papers)
    26% identity, 96% coverage of query (90.5 bits)

3lnpA / D3KFX9 Crystal structure of amidohydrolase family protein olei01672_1_465 from oleispira antarctica (see paper)
    24% identity, 90% coverage of query (84.0 bits)

4f0rA / Q7NZ90 Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) bound zn and 5'- methylthioadenosine (unproductive complex)
    24% identity, 87% coverage of query (83.2 bits)

4f0sA Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) with bound inosine.
    24% identity, 87% coverage of query (83.2 bits)

cyrG / B0LI30 CyrG from Cylindrospermopsis raciborskii AWT205 (see 2 papers)
    26% identity, 96% coverage of query (82.0 bits)

Q9HZ64 S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31) from Pseudomonas aeruginosa (see paper)
    24% identity, 89% coverage of query (73.6 bits)

4dykA / Q9HZ64 Crystal structure of an adenosine deaminase from pseudomonas aeruginosa pao1 (target nysgrc-200449) with bound zn
    24% identity, 89% coverage of query (73.2 bits)

4gbdA Crystal structure of adenosine deaminase from pseudomonas aeruginosa pao1 with bound zn and methylthio-coformycin
    24% identity, 89% coverage of query (73.2 bits)

4dzhA / Q8P8H1 Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn
    25% identity, 92% coverage of query (72.8 bits)

8is4A / A0A4Q9D6T1 Structure of an isocytosine specific deaminase vcz in complexed with 5-fu (see paper)
    24% identity, 79% coverage of query (70.1 bits)

IXPDE_UNKP / P0CI72 Isoxanthopterin deaminase; EC 3.5.4.11 from Unknown prokaryotic organism (see paper)
P0CI72 pterin deaminase (EC 3.5.4.11) from unidentified prokaryotic organism (see paper)
    26% identity, 81% coverage of query (68.6 bits)

2i9uA / Q97MB6 Crystal structure of guanine deaminase from c. Acetobutylicum with bound guanine in the active site
    22% identity, 83% coverage of query (67.4 bits)

dadD / Q58936 5'-deoxyadenosine deaminase monomer (EC 3.5.4.28; EC 3.5.4.4; EC 3.5.4.31; EC 3.5.4.41) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
DADD_METJA / Q58936 5'-deoxyadenosine deaminase; 5'-dA deaminase; 5'-methylthioadenosine deaminase; MTA deaminase; Adenosine deaminase; S-adenosylhomocysteine deaminase; SAH deaminase; EC 3.5.4.41; EC 3.5.4.31; EC 3.5.4.4; EC 3.5.4.28 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58936 S-adenosylhomocysteine deaminase (EC 3.5.4.28); S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31); adenosine deaminase (EC 3.5.4.4); 5'-deoxyadenosine deaminase (EC 3.5.4.41) from Methanocaldococcus jannaschii (see paper)
    21% identity, 85% coverage of query (65.5 bits)

atzA / P72156 AtzA (EC 3.8.1.8) from Pseudomonas sp. (strain ADP) (see 3 papers)
ATZA_PSESD / P72156 Atrazine chlorohydrolase; EC 3.8.1.8 from Pseudomonas sp. (strain ADP) (see 5 papers)
P72156 atrazine chlorohydrolase (EC 3.8.1.8) from Pseudomonas sp. ADP (see paper)
4v1xE / P72156 The structure of the hexameric atrazine chlorohydrolase, atza (see paper)
    25% identity, 84% coverage of query (64.7 bits)

Q8GG87 atrazine chlorohydrolase (EC 3.8.1.8) from Arthrobacter sp. (see paper)
    25% identity, 84% coverage of query (64.3 bits)

triA / Q9EYU0 melamine deaminase subunit (EC 3.5.4.45) from Paracidovorax citrulli (see 2 papers)
TRIA_PARCI / Q9EYU0 Melamine deaminase; EC 3.5.4.45 from Paracidovorax citrulli (Acidovorax citrulli) (see 3 papers)
Q9EYU0 melamine deaminase (EC 3.5.4.45) from Acidovorax citrulli (see 2 papers)
    24% identity, 84% coverage of query (54.3 bits)

6ohbA / P76641 E. Coli guanine deaminase (see paper)
    22% identity, 81% coverage of query (53.5 bits)

GuaD / b2883 guanine deaminase (EC 3.5.4.3) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
guaD / P76641 guanine deaminase (EC 3.5.4.3) from Escherichia coli (strain K12) (see paper)
GUAD_ECOLI / P76641 Guanine deaminase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH; EC 3.5.4.3 from Escherichia coli (strain K12) (see paper)
P76641 guanine deaminase (EC 3.5.4.3) from Escherichia coli (see paper)
    23% identity, 81% coverage of query (53.1 bits)

3hpaA Crystal structure of an amidohydrolase gi:44264246 from an evironmental sample of sargasso sea (see paper)
    22% identity, 92% coverage of query (52.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory