Searching for up to 100 curated homologs for N515DRAFT_0355 FitnessBrowser__Dyella79:N515DRAFT_0355 (326 a.a.)
Found high-coverage hits (≥70%) to 55 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
P21874 pyruvate dehydrogenase (acetyl-transferring) (EC 1.2.4.1) from Geobacillus stearothermophilus (see paper)
49% identity, 99% coverage of query (327 bits)
3dufD / P21874 Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multi-enzyme complex (see paper)
49% identity, 99% coverage of query (324 bits)
3dv0D Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multi-enzyme complex
49% identity, 99% coverage of query (324 bits)
3dv0B Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multi-enzyme complex
49% identity, 99% coverage of query (324 bits)
1w85B The crystal structure of pyruvate dehydrogenase e1 bound to the peripheral subunit binding domain of e2
49% identity, 99% coverage of query (324 bits)
ODPB_BACSU / P21882 Pyruvate dehydrogenase E1 component subunit beta; S complex, 36 kDa subunit; EC 1.2.4.1 from Bacillus subtilis (strain 168) (see 2 papers)
pdhB / AAC24933.1 pyruvate decarboxylase E-1 beta subunit from Bacillus subtilis (see 3 papers)
49% identity, 99% coverage of query (313 bits)
Q9HIA4 branched-chain-2-oxoacid decarboxylase (subunit 2/2) (EC 4.1.1.72) from Thermoplasma acidophilum (see paper)
49% identity, 98% coverage of query (313 bits)
ODPB_STAAU / P0A0A3 Pyruvate dehydrogenase E1 component subunit beta; EC 1.2.4.1 from Staphylococcus aureus (see paper)
45% identity, 99% coverage of query (310 bits)
SMc03202 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) from Sinorhizobium meliloti 1021
49% identity, 98% coverage of query (308 bits)
Pf6N2E2_480 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4) from Pseudomonas fluorescens FW300-N2E2
48% identity, 98% coverage of query (303 bits)
AO356_22985 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) from Pseudomonas fluorescens FW300-N2C3
48% identity, 98% coverage of query (303 bits)
PS417_17550 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) from Pseudomonas simiae WCS417
48% identity, 98% coverage of query (301 bits)
PfGW456L13_3541 branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) from Pseudomonas fluorescens GW456-L13
48% identity, 98% coverage of query (300 bits)
ODBB_THET8 / Q5SLR3 2-oxoisovalerate dehydrogenase subunit beta; Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta; EC 1.2.4.4 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
50% identity, 99% coverage of query (300 bits)
bfmBAB / P37941 2-keto-isovalerate dehydrogenase component β subunit (EC 1.2.4.4) from Bacillus subtilis (strain 168) (see 2 papers)
48% identity, 99% coverage of query (297 bits)
1umbD / Q5SLR3 Branched-chain 2-oxo acid dehydrogenase (e1) from thermus thermophilus hb8 in holo-form (see paper)
50% identity, 99% coverage of query (297 bits)
BKDB_MYCTU / P9WIS1 3-methyl-2-oxobutanoate dehydrogenase subunit beta; Branched-chain alpha-ketoacid dehydrogenase E1 component subunit beta; BCKADH E1-beta; EC 1.2.4.4 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
48% identity, 98% coverage of query (297 bits)
1umdD Branched-chain 2-oxo acid dehydrogenase (e1) from thermus thermophilus hb8 with 4-methyl-2-oxopentanoate as an intermediate
50% identity, 99% coverage of query (297 bits)
1umcD Branched-chain 2-oxo acid dehydrogenase (e1) from thermus thermophilus hb8 with 4-methylpentanoate
50% identity, 99% coverage of query (297 bits)
1qs0B / P09061 Crystal structure of pseudomonas putida 2-oxoisovalerate dehydrogenase (branched-chain alpha-keto acid dehydrogenase, e1b) (see paper)
46% identity, 99% coverage of query (295 bits)
bkdA2 / GI|790516 2-oxoisovalerate dehydrogenase subunit beta; EC 1.2.4.4 from Pseudomonas putida (see 2 papers)
46% identity, 99% coverage of query (295 bits)
ODBB2_ARATH / Q9LDY2 2-oxoisovalerate dehydrogenase subunit beta 2, mitochondrial; Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDE1B; BCKDH E1-beta; Protein DARK INDUCIBLE 4; EC 1.2.4.4 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
46% identity, 98% coverage of query (289 bits)
ppdcβ / G1UHX5 phenylpyruvate decarboxylase β subunit (EC 4.1.1.43) from Streptomyces virginiae (see paper)
48% identity, 98% coverage of query (283 bits)
pdhB / P75391 β subunit from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) (see 3 papers)
46% identity, 98% coverage of query (273 bits)
2j9fD / P21953 Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase e1b (see paper)
44% identity, 98% coverage of query (268 bits)
1dtwB Human branched-chain alpha-keto acid dehydrogenase
44% identity, 98% coverage of query (268 bits)
BCKDHB / P21953 branched-chain α-keto acid dehydrogenase E1 component β subunit (EC 1.2.4.4) from Homo sapiens (see 15 papers)
ODBB_HUMAN / P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial; Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDE1B; BCKDH E1-beta; EC 1.2.4.4 from Homo sapiens (Human) (see 5 papers)
P21953 branched-chain alpha-keto acid dehydrogenase system (subunit 1/2) (EC 1.2.1.25) from Homo sapiens (see 5 papers)
44% identity, 98% coverage of query (267 bits)
Q6P3A8 branched-chain alpha-keto acid dehydrogenase system (subunit 1/2) (EC 1.2.1.25) from Mus musculus (see paper)
43% identity, 98% coverage of query (266 bits)
P35738 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (subunit 1/2) (EC 1.2.4.4) from Rattus norvegicus (see paper)
43% identity, 98% coverage of query (266 bits)
ODBB_BOVIN / P21839 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial; Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDE1B; BCKDH E1-beta; EC 1.2.4.4 from Bos taurus (Bovine) (see paper)
43% identity, 98% coverage of query (265 bits)
Q46143 acetoin dehydrogenase system (EC 2.3.1.190) from Clostridium magnum (see paper)
acoB TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit; EC 1.1.1.- from Clostridium magnum (see paper)
AAA21745.1 TPP-dependent acetoin dehydrogenase beta-subunit from Clostridium magnum (see paper)
44% identity, 98% coverage of query (252 bits)
P73405 pyruvate dehydrogenase system (subunit 1/2) (EC 1.2.1.104); pyruvate dehydrogenase (acetyl-transferring) (subunit 1/2) (EC 1.2.4.1) from Synechocystis sp. PCC 6803 (see 2 papers)
44% identity, 92% coverage of query (241 bits)
A2Z2Z0 pyruvate dehydrogenase (acetyl-transferring) (subunit 1/2) (EC 1.2.4.1) from Oryza sativa Indica Group (see paper)
42% identity, 98% coverage of query (233 bits)
Q1KSF0 pyruvate dehydrogenase (acetyl-transferring) (EC 1.2.4.1) from Toxoplasma gondii (see paper)
41% identity, 97% coverage of query (231 bits)
P27746 acetoin dehydrogenase system (EC 2.3.1.190) from Alcaligenes eutrophus H16 (see paper)
acoB / AAA21949.1 acetoin:DCPIP oxidoreductase-beta from Cupriavidus necator (see paper)
44% identity, 98% coverage of query (231 bits)
ODPB1_ARATH / Q38799 Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial; PDHE1-B; Protein MACCI-BOU; EC 1.2.4.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q38799 pyruvate dehydrogenase system (subunit 1/2) (EC 1.2.1.104); pyruvate dehydrogenase (acetyl-transferring) (subunit 1/2) (EC 1.2.4.1) from Arabidopsis thaliana (see paper)
42% identity, 98% coverage of query (230 bits)
Q9HWN0 acetoin dehydrogenase system (subunit 1/2) (EC 2.3.1.190) from Pseudomonas aeruginosa (see paper)
44% identity, 98% coverage of query (229 bits)
P52904 pyruvate dehydrogenase system (subunit 3/3) (EC 1.2.1.104) from Pisum sativum (see paper)
41% identity, 98% coverage of query (214 bits)
ODPB_DROME / Q7K5K3 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; EC 1.2.4.1 from Drosophila melanogaster (Fruit fly) (see paper)
38% identity, 98% coverage of query (206 bits)
ODPB_SCHPO / Q09171 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; PDHE1-B; EC 1.2.4.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
pdb1 / RF|NP_596272.1 pyruvate dehydrogenase e1 component beta subunit Pdb1; EC 1.2.4.1 from Schizosaccharomyces pombe (see paper)
39% identity, 99% coverage of query (202 bits)
Q97YF5 acetoin dehydrogenase system (EC 2.3.1.190) from Saccharolobus solfataricus (see paper)
37% identity, 97% coverage of query (199 bits)
ODPB_YEAST / P32473 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; Pyruvate dehydrogenase complex component E1 beta; PDHE1-B; EC 1.2.4.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
37% identity, 99% coverage of query (197 bits)
PDHB / P26269 pyruvate dehydrogenase β subunit from Ascaris suum (see paper)
36% identity, 99% coverage of query (195 bits)
6cerD / P11177 Human pyruvate dehydrogenase complex e1 component v138m mutation (see paper)
34% identity, 99% coverage of query (190 bits)
PDHB / P11177 pyruvate dehydrogenase E1 component β subunit from Homo sapiens (see 7 papers)
ODPB_HUMAN / P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; PDHE1-B; EC 1.2.4.1 from Homo sapiens (Human) (see 7 papers)
P11177 pyruvate dehydrogenase system (subunit 1/2) (EC 1.2.1.104); pyruvate dehydrogenase (acetyl-transferring) (subunit 1/2) (EC 1.2.4.1) from Homo sapiens (see 2 papers)
34% identity, 99% coverage of query (190 bits)
6cfoB Human pyruvate dehydrogenase e1 component complex with covalent tdp adduct acetyl phosphinate
34% identity, 99% coverage of query (190 bits)
Q9D051 pyruvate dehydrogenase system (subunit 1/2) (EC 1.2.1.104) from Mus musculus (see paper)
35% identity, 99% coverage of query (189 bits)
Build an alignment for N515DRAFT_0355 and 47 homologs with ≥ 30% identity
Or download the sequences
6yakDDD 6yakDDD (see paper)
29% identity, 97% coverage of query (80.1 bits)
6xxgBBB / Q9RUB5 6xxgBBB (see paper)
25% identity, 75% coverage of query (48.5 bits)
6xxgAAA / Q9RUB5 6xxgAAA (see paper)
25% identity, 75% coverage of query (48.5 bits)
6ouwA 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus radiodurans with enamine intermediate bound
25% identity, 75% coverage of query (48.1 bits)
2o1xA 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from deinococcus radiodurans
25% identity, 75% coverage of query (48.1 bits)
8v9iA 1-deoxy-D-xylulose-5-phosphate synthase
25% identity, 75% coverage of query (48.1 bits)
6ouvA / Q9RUB5 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus radiodurans with methylacetylphosphonate (map) bound (see paper)
25% identity, 75% coverage of query (48.1 bits)
DXS_DEIRA / Q9RUB5 1-deoxy-D-xylulose-5-phosphate synthase; 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; EC 2.2.1.7 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
Q9RUB5 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Deinococcus radiodurans (see 2 papers)
25% identity, 75% coverage of query (48.1 bits)
Or start over
Lawrence Berkeley National Laboratory