Sites on a Tree

 

Searching for up to 100 curated homologs for N515DRAFT_0393 N515DRAFT_0393 glucokinase (333 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1sz2B / P0A6V9 Crystal structure of e. Coli glucokinase in complex with glucose (see paper)
    38% identity, 93% coverage of query (187 bits)

Glk / b2388 glucokinase (EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.8) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
glk / P0A6V8 glucokinase (EC 2.7.1.1; EC 2.7.1.8) from Escherichia coli (strain K12) (see 11 papers)
GLK_ECOLI / P0A6V8 Glucokinase; Glucose kinase; EC 2.7.1.2 from Escherichia coli (strain K12) (see paper)
    38% identity, 93% coverage of query (187 bits)

PS417_22685 Glucokinase (EC 2.7.1.2) from Pseudomonas simiae WCS417
    35% identity, 93% coverage of query (147 bits)

glk / AAC43672.1 glucokinase from Brucella abortus (see paper)
    35% identity, 94% coverage of query (145 bits)

Dshi_1655 glucokinase (EC 2.7.1.2) from Dinoroseobacter shibae DFL-12
    32% identity, 93% coverage of query (119 bits)

A0A3G4RI75 glucokinase (EC 2.7.1.2) from Methylomonas methanica (see paper)
    33% identity, 93% coverage of query (119 bits)

G4T1H4 glucokinase (EC 2.7.1.2) from Methylotuvimicrobium alcaliphilum (see paper)
    31% identity, 93% coverage of query (113 bits)

Build an alignment

Build an alignment for N515DRAFT_0393 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GL50803_8826 / E2RU42 glucokinase (EC 2.7.1.1) from Giardia intestinalis (strain ATCC 50803 / WB clone C6) (see 3 papers)
    27% identity, 94% coverage of query (99.0 bits)

PGA1_c05420 glucokinase (EC 2.7.1.2) from Phaeobacter inhibens BS107
    30% identity, 94% coverage of query (75.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory